felodipine-337 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the felodipine-337 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
AGFG2 ArfGAP with FG repeats 2
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASIC1 acid sensing (proton gated) ion channel 1
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATXN2L ataxin 2-like
B3GAT3 beta-1,3-glucuronyltransferase 3
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BIN1 bridging integrator 1
BRAP BRCA1 associated protein
CA1 carbonic anhydrase I
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CHD5 chromodomain helicase DNA binding protein 5
CHERP calcium homeostasis endoplasmic reticulum protein
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CROCC ciliary rootlet coiled-coil, rootletin
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCHS1 dachsous cadherin-related 1
DGCR2 DiGeorge syndrome critical region gene 2
DOCK9 dedicator of cytokinesis 9
ELMO3 engulfment and cell motility 3
EPHB1 EPH receptor B1
FAM110D family with sequence similarity 110, member D
FAM188A family with sequence similarity 188, member A
FCAR Fc fragment of IgA receptor
FOSL2 FOS-like antigen 2
FPR2 formyl peptide receptor 2
FUT2 fucosyltransferase 2 (secretor status included)
FYB FYN binding protein
GJC1 gap junction protein, gamma 1, 45kDa
GK glycerol kinase
GPR32 G protein-coupled receptor 32
GPR4 G protein-coupled receptor 4
GSK3A glycogen synthase kinase 3 alpha
HOXA11 homeobox A11
HOXB7 homeobox B7
HOXC5 homeobox C5
ICAM1 intercellular adhesion molecule 1
IGFALS insulin-like growth factor binding protein, acid labile subunit
IL11 interleukin 11
IL13 interleukin 13
IL5RA interleukin 5 receptor, alpha
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA1467 KIAA1467
L1CAM L1 cell adhesion molecule
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LHX2 LIM homeobox 2
LPPR2 lipid phosphate phosphatase-related protein type 2
MERTK MER proto-oncogene, tyrosine kinase
MINK1 misshapen-like kinase 1
MPPE1 metallophosphoesterase 1
NADK NAD kinase
NOX1 NADPH oxidase 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRGN neurogranin (protein kinase C substrate, RC3)
OVOL1 ovo-like zinc finger 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDLIM4 PDZ and LIM domain 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIDD1 p53-induced death domain protein 1
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PYGM phosphorylase, glycogen, muscle
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
SCARB1 scavenger receptor class B, member 1
SCLY selenocysteine lyase
SCNN1B sodium channel, non voltage gated 1 beta subunit
SH3GL3 SH3-domain GRB2-like 3
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SPN sialophorin
SPP2 secreted phosphoprotein 2, 24kDa
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STAB1 stabilin 1
STAG3 stromal antigen 3
STARD8 StAR-related lipid transfer (START) domain containing 8
STX2 syntaxin 2
SYNGR1 synaptogyrin 1
TBL1X transducin (beta)-like 1X-linked
TBR1 T-box, brain, 1
TCEA2 transcription elongation factor A (SII), 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAC T cell receptor alpha constant
TTLL4 tubulin tyrosine ligase-like family member 4
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WIPF1 WAS/WASL interacting protein family, member 1

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
AHR aryl hydrocarbon receptor
AMOT angiomotin
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA10 annexin A10
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BHMT betaine--homocysteine S-methyltransferase
BIRC7 baculoviral IAP repeat containing 7
C1ORF54 chromosome 1 open reading frame 54
CA5BP1 carbonic anhydrase VB pseudogene 1
CCL4 chemokine (C-C motif) ligand 4
CCNA1 cyclin A1
CDH22 cadherin 22, type 2
CDK6 cyclin-dependent kinase 6
CENPO centromere protein O
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCN2 chloride channel, voltage-sensitive 2
CLCN5 chloride channel, voltage-sensitive 5
CST8 cystatin 8 (cystatin-related epididymal specific)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
ESPN espin
FGF17 fibroblast growth factor 17
FGF22 fibroblast growth factor 22
FOLR2 folate receptor 2 (fetal)
GAB2 GRB2-associated binding protein 2
GLMN glomulin, FKBP associated protein
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GUSBP3 glucuronidase, beta pseudogene 3
HDAC11 histone deacetylase 11
HIST1H2AI histone cluster 1, H2ai
HPGDS hematopoietic prostaglandin D synthase
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IGKV1D-13 immunoglobulin kappa variable 1D-13
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KDM5D lysine (K)-specific demethylase 5D
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
L1TD1 LINE-1 type transposase domain containing 1
LDHC lactate dehydrogenase C
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIAS lipoic acid synthetase
LMTK1 lemur tail kinase 1
LY6D lymphocyte antigen 6 complex, locus D
MAGEA5 melanoma antigen family A5
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MATK megakaryocyte-associated tyrosine kinase
MEPE matrix extracellular phosphoglycoprotein
MIR600HG MIR600 host gene
MN1 meningioma (disrupted in balanced translocation) 1
MXRA5 matrix-remodelling associated 5
NLRP2 NLR family, pyrin domain containing 2
NNAT neuronatin
NXPH3 neurexophilin 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCDHA5 protocadherin alpha 5
PCDHB3 protocadherin beta 3
PDE11A phosphodiesterase 11A
PLA2G2E phospholipase A2, group IIE
PNMT phenylethanolamine N-methyltransferase
POGLUT1 protein O-glucosyltransferase 1
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PRSS50 protease, serine, 50
RAB33B RAB33B, member RAS oncogene family
RCAN2 regulator of calcineurin 2
RFWD3 ring finger and WD repeat domain 3
RNF185 ring finger protein 185
ROPN1B rhophilin associated tail protein 1B
RPL23AP32 ribosomal protein L23a pseudogene 32
SATB1 SATB homeobox 1
SCAI suppressor of cancer cell invasion
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC35F5 solute carrier family 35, member F5
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAT5A signal transducer and activator of transcription 5A
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
T T, brachyury homolog (mouse)
TICAM1 toll-like receptor adaptor molecule 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMLHE trimethyllysine hydroxylase, epsilon
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TUBA4B tubulin, alpha 4b
TUBB1 tubulin, beta 1 class VI
WDR13 WD repeat domain 13
ZC4H2 zinc finger, C4H2 domain containing
ZNF160 zinc finger protein 160
ZNF276 zinc finger protein 276
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF654 zinc finger protein 654