| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the felodipine-5294 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACTN1 | actinin, alpha 1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARMC4 | armadillo repeat containing 4 |
| ATF3 | activating transcription factor 3 |
| BBS9 | Bardet-Biedl syndrome 9 |
| CABIN1 | calcineurin binding protein 1 |
| CCNT2 | cyclin T2 |
| CD44 | CD44 molecule (Indian blood group) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CIC | capicua transcriptional repressor |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| CUL9 | cullin 9 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DMC1 | DNA meiotic recombinase 1 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP8 | dual specificity phosphatase 8 |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXO22 | F-box protein 22 |
| FCHO1 | FCH domain only 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR87 | G protein-coupled receptor 87 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H3B | histone cluster 1, H3b |
| HMOX1 | heme oxygenase 1 |
| IER2 | immediate early response 2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IRF1 | interferon regulatory factor 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JUN | jun proto-oncogene |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KITLG | KIT ligand |
| KLF10 | Kruppel-like factor 10 |
| KLF6 | Kruppel-like factor 6 |
| KLHL25 | kelch-like family member 25 |
| KRT17 | keratin 17, type I |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LIF | leukemia inhibitory factor |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LRRC20 | leucine rich repeat containing 20 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MST1 | macrophage stimulating 1 |
| NF1 | neurofibromin 1 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIAS4 | protein inhibitor of activated STAT, 4 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLAUR | plasminogen activator, urokinase receptor |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRLR | prolactin receptor |
| PTRF | polymerase I and transcript release factor |
| RANBP1 | RAN binding protein 1 |
| RCAN1 | regulator of calcineurin 1 |
| REC8 | REC8 meiotic recombination protein |
| REEP1 | receptor accessory protein 1 |
| RNF19B | ring finger protein 19B |
| RNF2 | ring finger protein 2 |
| RPL10 | ribosomal protein L10 |
| RPL35A | ribosomal protein L35a |
| SCHIP1 | schwannomin interacting protein 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STON1 | stonin 1 |
| TAOK1 | TAO kinase 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TSPAN31 | tetraspanin 31 |
| ULBP2 | UL16 binding protein 2 |
| VEGFA | vascular endothelial growth factor A |
| WDR62 | WD repeat domain 62 |
| WIZ | widely interspaced zinc finger motifs |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF750 | zinc finger protein 750 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACTN4 | actinin, alpha 4 |
| ADCY3 | adenylate cyclase 3 |
| AKTIP | AKT interacting protein |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| BBS10 | Bardet-Biedl syndrome 10 |
| BCAS4 | breast carcinoma amplified sequence 4 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| CENPC | centromere protein C |
| CHN1 | chimerin 1 |
| COL9A2 | collagen, type IX, alpha 2 |
| CUEDC1 | CUE domain containing 1 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DNM1 | dynamin 1 |
| EFHD1 | EF-hand domain family, member D1 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| FAM169A | family with sequence similarity 169, member A |
| FBXO3 | F-box protein 3 |
| FBXO46 | F-box protein 46 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| GMPPA | GDP-mannose pyrophosphorylase A |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 |
| H2AFJ | H2A histone family, member J |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXC6 | homeobox C6 |
| IGFLR1 | IGF-like family receptor 1 |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| JRKL | JRK-like |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LMNB1 | lamin B1 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP9 | microtubule-associated protein 9 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| METTL2B | methyltransferase like 2B |
| MICU1 | mitochondrial calcium uptake 1 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MSMO1 | methylsterol monooxygenase 1 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NEO1 | neogenin 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NXN | nucleoredoxin |
| OCEL1 | occludin/ELL domain containing 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PAQR3 | progestin and adipoQ receptor family member III |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTER | phosphotriesterase related |
| PTK6 | protein tyrosine kinase 6 |
| RBM15B | RNA binding motif protein 15B |
| RBM41 | RNA binding motif protein 41 |
| RBM42 | RNA binding motif protein 42 |
| RCOR3 | REST corepressor 3 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RINT1 | RAD50 interactor 1 |
| RNF123 | ring finger protein 123 |
| RUFY2 | RUN and FYVE domain containing 2 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SOX3 | SRY (sex determining region Y)-box 3 |
| TEFM | transcription elongation factor, mitochondrial |
| TESK2 | testis-specific kinase 2 |
| THEM6 | thioesterase superfamily member 6 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TLN1 | talin 1 |
| TMEM38B | transmembrane protein 38B |
| TMEM39B | transmembrane protein 39B |
| TRAF5 | TNF receptor-associated factor 5 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSPYL5 | TSPY-like 5 |
| WLS | wntless Wnt ligand secretion mediator |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF329 | zinc finger protein 329 |
| ZNF813 | zinc finger protein 813 |