felodipine-848 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the felodipine-848 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK2 aarF domain containing kinase 2
AOX1 aldehyde oxidase 1
ARC activity-regulated cytoskeleton-associated protein
AREG amphiregulin
ATF3 activating transcription factor 3
ATF6 activating transcription factor 6
BDKRB2 bradykinin receptor B2
BHLHE40 basic helix-loop-helix family, member e40
BMP2K BMP2 inducible kinase
CCPG1 cell cycle progression 1
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CRELD1 cysteine-rich with EGF-like domains 1
CRY2 cryptochrome circadian clock 2
CUZD1 CUB and zona pellucida-like domains 1
DDIT3 DNA-damage-inducible transcript 3
DLX2 distal-less homeobox 2
DNMBP dynamin binding protein
DOCK6 dedicator of cytokinesis 6
DSCAM Down syndrome cell adhesion molecule
DSTYK dual serine/threonine and tyrosine protein kinase
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
E2F4 E2F transcription factor 4, p107/p130-binding
EFNA1 ephrin-A1
EGR1 early growth response 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPOR erythropoietin receptor
EPS8L1 EPS8-like 1
ESR1 estrogen receptor 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV5 ets variant 5
FAM49B family with sequence similarity 49, member B
FASTK Fas-activated serine/threonine kinase
FOS FBJ murine osteosarcoma viral oncogene homolog
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
HES1 hes family bHLH transcription factor 1
HIST1H2AE histone cluster 1, H2ae
HIST1H2BG histone cluster 1, H2bg
HIST1H3B histone cluster 1, H3b
HIST2H2BE histone cluster 2, H2be
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
ICAM1 intercellular adhesion molecule 1
IER2 immediate early response 2
IFITM1 interferon induced transmembrane protein 1
INHBE inhibin, beta E
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRF1 interferon regulatory factor 1
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MKL1 megakaryoblastic leukemia (translocation) 1
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRF1 nuclear respiratory factor 1
OPTN optineurin
OSMR oncostatin M receptor
PCM1 pericentriolar material 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
POMT2 protein-O-mannosyltransferase 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RAB3A RAB3A, member RAS oncogene family
RCAN1 regulator of calcineurin 1
RECQL5 RecQ protein-like 5
RND1 Rho family GTPase 1
SAFB2 scaffold attachment factor B2
SCAMP1 secretory carrier membrane protein 1
SIK1 salt-inducible kinase 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SMTN smoothelin
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SRCAP Snf2-related CREBBP activator protein
SSPN sarcospan
STK17B serine/threonine kinase 17b
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFF2 trefoil factor 2
TJAP1 tight junction associated protein 1 (peripheral)
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TXNIP thioredoxin interacting protein
WSB1 WD repeat and SOCS box containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZFP36 ZFP36 ring finger protein
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF253 zinc finger protein 253
ZNF442 zinc finger protein 442
ZNF473 zinc finger protein 473

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACSF2 acyl-CoA synthetase family member 2
ACYP1 acylphosphatase 1, erythrocyte (common) type
AKIP1 A kinase (PRKA) interacting protein 1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APIP APAF1 interacting protein
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARRB1 arrestin, beta 1
ATG2A autophagy related 2A
BMP4 bone morphogenetic protein 4
BPGM 2,3-bisphosphoglycerate mutase
C6ORF47 chromosome 6 open reading frame 47
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COCH cochlin
CXORF56 chromosome X open reading frame 56
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ERI3 ERI1 exoribonuclease family member 3
ERO1L ERO1-like (S. cerevisiae)
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FZD2 frizzled class receptor 2
HIST1H2AI histone cluster 1, H2ai
HLA-J major histocompatibility complex, class I, J (pseudogene)
HSPA1L heat shock 70kDa protein 1-like
HSPA2 heat shock 70kDa protein 2
HSPB8 heat shock 22kDa protein 8
IGBP1 immunoglobulin (CD79A) binding protein 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KRT15 keratin 15, type I
LHX6 LIM homeobox 6
LIME1 Lck interacting transmembrane adaptor 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRP3 low density lipoprotein receptor-related protein 3
LZTR1 leucine-zipper-like transcription regulator 1
MANEA mannosidase, endo-alpha
MAP9 microtubule-associated protein 9
MED15 mediator complex subunit 15
MEX3C mex-3 RNA binding family member C
MFAP2 microfibrillar-associated protein 2
MOSPD3 motile sperm domain containing 3
MTSS1L metastasis suppressor 1-like
MVD mevalonate (diphospho) decarboxylase
MXD3 MAX dimerization protein 3
NFE2L3 nuclear factor, erythroid 2-like 3
NLRX1 NLR family member X1
NMU neuromedin U
NPY1R neuropeptide Y receptor Y1
NUP62CL nucleoporin 62kDa C-terminal like
NUPL2 nucleoporin like 2
OXCT1 3-oxoacid CoA transferase 1
OXR1 oxidation resistance 1
PAQR6 progestin and adipoQ receptor family member VI
PELP1 proline, glutamate and leucine rich protein 1
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PROCR protein C receptor, endothelial
PRSS22 protease, serine, 22
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB23 RAB23, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIBC2 RIB43A domain with coiled-coils 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNHG3 small nucleolar RNA host gene 3
SOX12 SRY (sex determining region Y)-box 12
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
SSFA2 sperm specific antigen 2
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYNJ2BP synaptojanin 2 binding protein
TBC1D17 TBC1 domain family, member 17
TCTN2 tectonic family member 2
TET3 tet methylcytosine dioxygenase 3
TICAM1 toll-like receptor adaptor molecule 1
TMA7 translation machinery associated 7 homolog (S. cerevisiae)
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM184C transmembrane protein 184C
TMUB2 transmembrane and ubiquitin-like domain containing 2
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEGFB vascular endothelial growth factor B
WWC2 WW and C2 domain containing 2
XYLT2 xylosyltransferase II
ZMYM1 zinc finger, MYM-type 1
ZNF552 zinc finger protein 552
ZNF668 zinc finger protein 668
ZNF767P zinc finger family member 767, pseudogene
ZNF813 zinc finger protein 813