| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the felodipine-965 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ARC | activity-regulated cytoskeleton-associated protein |
| AREG | amphiregulin |
| ATF3 | activating transcription factor 3 |
| AURKA | aurora kinase A |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDKN2AIP | CDKN2A interacting protein |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CGA | glycoprotein hormones, alpha polypeptide |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DLX2 | distal-less homeobox 2 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAM188A | family with sequence similarity 188, member A |
| FLOT1 | flotillin 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSL1 | FOS-like antigen 1 |
| FOSL2 | FOS-like antigen 2 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HBEGF | heparin-binding EGF-like growth factor |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HES1 | hes family bHLH transcription factor 1 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3H | histone cluster 1, H3h |
| HIST1H4H | histone cluster 1, H4h |
| HIST2H2BE | histone cluster 2, H2be |
| ICAM1 | intercellular adhesion molecule 1 |
| IER2 | immediate early response 2 |
| IER5 | immediate early response 5 |
| IRF1 | interferon regulatory factor 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF2 | Kruppel-like factor 2 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLF6 | Kruppel-like factor 6 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MCL1 | myeloid cell leukemia 1 |
| MED6 | mediator complex subunit 6 |
| MMP19 | matrix metallopeptidase 19 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NKX3-1 | NK3 homeobox 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PER1 | period circadian clock 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTBP2 | polypyrimidine tract binding protein 2 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RCAN1 | regulator of calcineurin 1 |
| RND1 | Rho family GTPase 1 |
| SIK1 | salt-inducible kinase 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRIB1 | tribbles pseudokinase 1 |
| TUFT1 | tuftelin 1 |
| TXNIP | thioredoxin interacting protein |
| USP36 | ubiquitin specific peptidase 36 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ANKRD36 | ankyrin repeat domain 36 |
| APOC1 | apolipoprotein C-I |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BBC3 | BCL2 binding component 3 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL9 | B-cell CLL/lymphoma 9 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BMP4 | bone morphogenetic protein 4 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CARD8 | caspase recruitment domain family, member 8 |
| CENPQ | centromere protein Q |
| CLSPN | claspin |
| CROT | carnitine O-octanoyltransferase |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEPDC1 | DEP domain containing 1 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| EHD3 | EH-domain containing 3 |
| EPHA4 | EPH receptor A4 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAAH | fatty acid amide hydrolase |
| FAM134B | family with sequence similarity 134, member B |
| FANCE | Fanconi anemia, complementation group E |
| FBXO3 | F-box protein 3 |
| FPGT | fucose-1-phosphate guanylyltransferase |
| FZD2 | frizzled class receptor 2 |
| GALT | galactose-1-phosphate uridylyltransferase |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GMIP | GEM interacting protein |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HPSE | heparanase |
| IFI35 | interferon-induced protein 35 |
| IGFLR1 | IGF-like family receptor 1 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IPO8 | importin 8 |
| JRKL | JRK-like |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KIFC1 | kinesin family member C1 |
| KRT13 | keratin 13, type I |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMNB1 | lamin B1 |
| LOC100287590 | uncharacterized LOC100287590 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAP7D3 | MAP7 domain containing 3 |
| MCOLN1 | mucolipin 1 |
| MTMR6 | myotubularin related protein 6 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB33B | RAB33B, member RAS oncogene family |
| RBL1 | retinoblastoma-like 1 |
| RLN2 | relaxin 2 |
| RNF31 | ring finger protein 31 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPANXC | SPANX family, member C |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STK16 | serine/threonine kinase 16 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TPCN1 | two pore segment channel 1 |
| TRIM5 | tripartite motif containing 5 |
| TSPAN1 | tetraspanin 1 |
| TWF2 | twinfilin actin binding protein 2 |
| WDR25 | WD repeat domain 25 |
| WDR4 | WD repeat domain 4 |
| XYLT2 | xylosyltransferase II |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF432 | zinc finger protein 432 |
| ZNF639 | zinc finger protein 639 |
| ZNF668 | zinc finger protein 668 |
| ZNF778 | zinc finger protein 778 |
