fenbendazole-2360 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the fenbendazole-2360 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AQP9 aquaporin 9
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARL15 ADP-ribosylation factor-like 15
ATF7IP activating transcription factor 7 interacting protein
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BBS4 Bardet-Biedl syndrome 4
BCL3 B-cell CLL/lymphoma 3
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CD86 CD86 molecule
CDRT1 CMT1A duplicated region transcript 1
CEP250 centrosomal protein 250kDa
CIDEC cell death-inducing DFFA-like effector c
COBLL1 cordon-bleu WH2 repeat protein-like 1
CRABP2 cellular retinoic acid binding protein 2
CREM cAMP responsive element modulator
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOC2A double C2-like domains, alpha
DOK3 docking protein 3
EMX1 empty spiracles homeobox 1
EXT1 exostosin glycosyltransferase 1
F11R F11 receptor
FAM13C family with sequence similarity 13, member C
FAM63A family with sequence similarity 63, member A
FBXO40 F-box protein 40
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FLJ11292
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GBP2 guanylate binding protein 2, interferon-inducible
GDAP1 ganglioside induced differentiation associated protein 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNS glucosamine (N-acetyl)-6-sulfatase
GPR19 G protein-coupled receptor 19
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXA9 homeobox A9
IL10RA interleukin 10 receptor, alpha
IL18RAP interleukin 18 receptor accessory protein
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
IL22 interleukin 22
KIAA0513 KIAA0513
KIAA1024 KIAA1024
KIAA1109 KIAA1109
KPTN kaptin (actin binding protein)
KRT81 keratin 81, type II
KYNU kynureninase
LGALS14 lectin, galactoside-binding, soluble, 14
LRRTM2 leucine rich repeat transmembrane neuronal 2
MAG myelin associated glycoprotein
MEF2C myocyte enhancer factor 2C
MIA2 melanoma inhibitory activity 2
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTSS1L metastasis suppressor 1-like
MVK mevalonate kinase
N4BP2L1 NEDD4 binding protein 2-like 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PDLIM5 PDZ and LIM domain 5
PICALM phosphatidylinositol binding clathrin assembly protein
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PLSCR1 phospholipid scramblase 1
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PTGDR2 prostaglandin D2 receptor 2
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RET ret proto-oncogene
RNF19B ring finger protein 19B
RPL13P5 ribosomal protein L13 pseudogene 5
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SC5D sterol-C5-desaturase
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDC2 syndecan 2
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRPA signal-regulatory protein alpha
SLC12A8 solute carrier family 12, member 8
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SNPH syntaphilin
SPRED2 sprouty-related, EVH1 domain containing 2
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN5 spectrin, beta, non-erythrocytic 5
SYT2 synaptotagmin II
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TM4SF5 transmembrane 4 L six family member 5
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TPM4 tropomyosin 4
TRBC1 T cell receptor beta constant 1
WDR1 WD repeat domain 1
ZNF337 zinc finger protein 337
ZNF675 zinc finger protein 675
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ARRB2 arrestin, beta 2
ASB6 ankyrin repeat and SOCS box containing 6
BAD BCL2-associated agonist of cell death
C19ORF40 chromosome 19 open reading frame 40
C1ORF35 chromosome 1 open reading frame 35
C6ORF47 chromosome 6 open reading frame 47
CCDC6 coiled-coil domain containing 6
CD37 CD37 molecule
CIR1 corepressor interacting with RBPJ, 1
CLEC16A C-type lectin domain family 16, member A
COMMD10 COMM domain containing 10
CPPED1 calcineurin-like phosphoesterase domain containing 1
CPTP ceramide-1-phosphate transfer protein
CYSLTR1 cysteinyl leukotriene receptor 1
DAAM1 dishevelled associated activator of morphogenesis 1
DBR1 debranching RNA lariats 1
DDN dendrin
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DENND4C DENN/MADD domain containing 4C
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EFHC1 EF-hand domain (C-terminal) containing 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ENAH enabled homolog (Drosophila)
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERN2 endoplasmic reticulum to nucleus signaling 2
FJX1 four jointed box 1 (Drosophila)
FKBPL FK506 binding protein like
FLJ21369 uncharacterized protein FLJ21369
GAB2 GRB2-associated binding protein 2
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPATCH3 G patch domain containing 3
GPR22 G protein-coupled receptor 22
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
ICK intestinal cell (MAK-like) kinase
KAT2A K(lysine) acetyltransferase 2A
KDM5C lysine (K)-specific demethylase 5C
KIAA0894 KIAA0894 protein
KIF3B kinesin family member 3B
KLK5 kallikrein-related peptidase 5
LRP3 low density lipoprotein receptor-related protein 3
MBD5 methyl-CpG binding domain protein 5
MECR mitochondrial trans-2-enoyl-CoA reductase
MED24 mediator complex subunit 24
METRN meteorin, glial cell differentiation regulator
NAT6 N-acetyltransferase 6 (GCN5-related)
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NRGN neurogranin (protein kinase C substrate, RC3)
NT5M 5',3'-nucleotidase, mitochondrial
PCYOX1 prenylcysteine oxidase 1
PHACTR4 phosphatase and actin regulator 4
PLA2G15 phospholipase A2, group XV
PLCB4 phospholipase C, beta 4
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PTCD2 pentatricopeptide repeat domain 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RARS arginyl-tRNA synthetase
RBM47 RNA binding motif protein 47
RFXAP regulatory factor X-associated protein
RPS21 ribosomal protein S21
SDF2 stromal cell-derived factor 2
SETD1B SET domain containing 1B
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SMR3A submaxillary gland androgen regulated protein 3A
SND1-IT1 SND1 intronic transcript 1
SNIP1 Smad nuclear interacting protein 1
SPIDR scaffolding protein involved in DNA repair
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SRD5A3 steroid 5 alpha-reductase 3
SREK1IP1 SREK1-interacting protein 1
STEAP3 STEAP family member 3, metalloreductase
SYNJ2BP synaptojanin 2 binding protein
TFIP11 tuftelin interacting protein 11
TMEM115 transmembrane protein 115
TMEM159 transmembrane protein 159
TMEM184C transmembrane protein 184C
TMEM62 transmembrane protein 62
TRAPPC13 trafficking protein particle complex 13
TRIM68 tripartite motif containing 68
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb
TUBGCP5 tubulin, gamma complex associated protein 5
VARS valyl-tRNA synthetase
YEATS2 YEATS domain containing 2
YIPF1 Yip1 domain family, member 1
ZBTB39 zinc finger and BTB domain containing 39
ZMAT5 zinc finger, matrin-type 5
ZNF180 zinc finger protein 180
ZNF324 zinc finger protein 324
ZNF35 zinc finger protein 35
ZNF37BP zinc finger protein 37B, pseudogene
ZNF767P zinc finger family member 767, pseudogene
ZNF770 zinc finger protein 770
ZNHIT2 zinc finger, HIT-type containing 2