fenbendazole-3805 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the fenbendazole-3805 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ABI2 abl-interactor 2
ALPP alkaline phosphatase, placental
APOF apolipoprotein F
ATP9A ATPase, class II, type 9A
BMP8B bone morphogenetic protein 8b
C21ORF2 chromosome 21 open reading frame 2
C9ORF156 chromosome 9 open reading frame 156
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCL24 chemokine (C-C motif) ligand 24
CDK19 cyclin-dependent kinase 19
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CGA glycoprotein hormones, alpha polypeptide
CLEC2B C-type lectin domain family 2, member B
CLIC5 chloride intracellular channel 5
CNGB1 cyclic nucleotide gated channel beta 1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CNTD2 cyclin N-terminal domain containing 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL7A1 collagen, type VII, alpha 1
CST1 cystatin SN
CT62 cancer/testis antigen 62
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYSLTR1 cysteinyl leukotriene receptor 1
DICER1 dicer 1, ribonuclease type III
EML2 echinoderm microtubule associated protein like 2
ESR2 estrogen receptor 2 (ER beta)
FAM174B family with sequence similarity 174, member B
FOXD2 forkhead box D2
FZD5 frizzled class receptor 5
GCGR glucagon receptor
GPRC5D G protein-coupled receptor, class C, group 5, member D
GSTTP1 glutathione S-transferase theta pseudogene 1
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFITM1 interferon induced transmembrane protein 1
IFNA1 interferon, alpha 1
IL6 interleukin 6
INSR insulin receptor
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIF1C kinesin family member 1C
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLHL18 kelch-like family member 18
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LCAT lecithin-cholesterol acyltransferase
LCT lactase
LRRC23 leucine rich repeat containing 23
LRRC31 leucine rich repeat containing 31
LTB4R leukotriene B4 receptor
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MMP12 matrix metallopeptidase 12
MNMIP1 manchette microtubule inner protein 1
MTSS1 metastasis suppressor 1
NF1 neurofibromin 1
NOX3 NADPH oxidase 3
NRCAM neuronal cell adhesion molecule
NUDC nudC nuclear distribution protein
OASL 2'-5'-oligoadenylate synthetase-like
ODAM odontogenic, ameloblast asssociated
OLFM1 olfactomedin 1
PCDH12 protocadherin 12
PDZRN3 PDZ domain containing ring finger 3
PHOX2B paired-like homeobox 2b
PLA2G3 phospholipase A2, group III
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRM2 protamine 2
PRTN3 proteinase 3
RAB6A RAB6A, member RAS oncogene family
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
SAA3P serum amyloid A3 pseudogene
SARDH sarcosine dehydrogenase
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SORBS2 sorbin and SH3 domain containing 2
SPATA6 spermatogenesis associated 6
SPN sialophorin
SPPL2B signal peptide peptidase like 2B
STOML1 stomatin (EPB72)-like 1
SYNDIG1 synapse differentiation inducing 1
SYT12 synaptotagmin XII
TAS2R1 taste receptor, type 2, member 1
TBKBP1 TBK1 binding protein 1
TFR2 transferrin receptor 2
THPO thrombopoietin
TM4SF4 transmembrane 4 L six family member 4
TMEM59L transmembrane protein 59-like
TNXB tenascin XB
TRH thyrotropin-releasing hormone
UBASH3A ubiquitin associated and SH3 domain containing A
VAV2 vav 2 guanine nucleotide exchange factor
WNT1 wingless-type MMTV integration site family, member 1

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ANP32A-IT1 ANP32A intronic transcript 1
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARSJ arylsulfatase family, member J
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BATF3 basic leucine zipper transcription factor, ATF-like 3
BMP4 bone morphogenetic protein 4
C11ORF73 chromosome 11 open reading frame 73
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5ORF42 chromosome 5 open reading frame 42
CAMKMT calmodulin-lysine N-methyltransferase
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CD70 CD70 molecule
CISH cytokine inducible SH2-containing protein
CLSTN3 calsyntenin 3
COBL cordon-bleu WH2 repeat protein
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPED1 cadherin-like and PC-esterase domain containing 1
CSRNP3 cysteine-serine-rich nuclear protein 3
CUZD1 CUB and zona pellucida-like domains 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DMTN dematin actin binding protein
DNA2 DNA replication helicase/nuclease 2
DUSP2 dual specificity phosphatase 2
DUSP9 dual specificity phosphatase 9
EFNB1 ephrin-B1
EN1 engrailed homeobox 1
EREG epiregulin
FAM86C1 family with sequence similarity 86, member C1
FBXO31 F-box protein 31
FBXO5 F-box protein 5
GAA glucosidase, alpha; acid
GLI3 GLI family zinc finger 3
GLT8D2 glycosyltransferase 8 domain containing 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRWD1 glutamate-rich WD repeat containing 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC7 histone deacetylase 7
HIST1H2BM histone cluster 1, H2bm
HIST1H4C histone cluster 1, H4c
HIST2H2AA3 histone cluster 2, H2aa3
HOXA1 homeobox A1
IFT54 intraflagellar transport 54
IL11RA interleukin 11 receptor, alpha
IL17RB interleukin 17 receptor B
IL33 interleukin 33
IQCG IQ motif containing G
JUNB jun B proto-oncogene
KCTD15 potassium channel tetramerization domain containing 15
KCTD17 potassium channel tetramerization domain containing 17
KDM8 lysine (K)-specific demethylase 8
L2HGDH L-2-hydroxyglutarate dehydrogenase
LOC157562 uncharacterized LOC157562
LOC390998 ribosomal protein L10 pseudogene
LYPD3 LY6/PLAUR domain containing 3
MANSC1 MANSC domain containing 1
MN1 meningioma (disrupted in balanced translocation) 1
MON1B MON1 secretory trafficking family member B
MTERF4 mitochondrial transcription termination factor 4
MTMR6 myotubularin related protein 6
MUC3A mucin 3A, cell surface associated
MYLIP myosin regulatory light chain interacting protein
NAT6 N-acetyltransferase 6 (GCN5-related)
NOL12 nucleolar protein 12
NT5M 5',3'-nucleotidase, mitochondrial
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSR2 odd-skipped related transciption factor 2
PAQR6 progestin and adipoQ receptor family member VI
PLD2 phospholipase D2
PMCH pro-melanin-concentrating hormone
POMT2 protein-O-mannosyltransferase 2
PRPH peripherin
PRR7 proline rich 7 (synaptic)
QSER1 glutamine and serine rich 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCUBE3 signal peptide, CUB domain, EGF-like 3
SETD6 SET domain containing 6
SLAMF7 SLAM family member 7
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLMO1 slowmo homolog 1 (Drosophila)
SOBP sine oculis binding protein homolog (Drosophila)
SPTBN2 spectrin, beta, non-erythrocytic 2
TCEAL2 transcription elongation factor A (SII)-like 2
TET3 tet methylcytosine dioxygenase 3
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THRB thyroid hormone receptor, beta
TIGD6 tigger transposable element derived 6
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNRC6B trinucleotide repeat containing 6B
TUBA4A tubulin, alpha 4a
XDH xanthine dehydrogenase
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF446 zinc finger protein 446
ZNF492 zinc finger protein 492
ZNF768 zinc finger protein 768