fenbendazole-3888 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the fenbendazole-3888 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ACPP acid phosphatase, prostate
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AREG amphiregulin
ATF3 activating transcription factor 3
ATF6B activating transcription factor 6 beta
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BDKRB2 bradykinin receptor B2
BIRC3 baculoviral IAP repeat containing 3
BTN3A1 butyrophilin, subfamily 3, member A1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C4BPA complement component 4 binding protein, alpha
C8ORF4 chromosome 8 open reading frame 4
CASR calcium-sensing receptor
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CLTA clathrin, light chain A
COL16A1 collagen, type XVI, alpha 1
COMT catechol-O-methyltransferase
CPB1 carboxypeptidase B1 (tissue)
CREBBP CREB binding protein
CXCR6 chemokine (C-X-C motif) receptor 6
DDIT3 DNA-damage-inducible transcript 3
DRD2 dopamine receptor D2
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
ERO1LB ERO1-like beta (S. cerevisiae)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM129A family with sequence similarity 129, member A
FBLN1 fibulin 1
FBXL18 F-box and leucine-rich repeat protein 18
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FKBP10 FK506 binding protein 10, 65 kDa
GFER growth factor, augmenter of liver regeneration
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GGT1 gamma-glutamyltransferase 1
GPR182 G protein-coupled receptor 182
GRM1 glutamate receptor, metabotropic 1
GSK3A glycogen synthase kinase 3 alpha
HBEGF heparin-binding EGF-like growth factor
HMOX1 heme oxygenase 1
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
IFNA14 interferon, alpha 14
IL21R interleukin 21 receptor
IL23A interleukin 23, alpha subunit p19
IL6 interleukin 6
INHBE inhibin, beta E
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
KCNK10 potassium channel, two pore domain subfamily K, member 10
LARP6 La ribonucleoprotein domain family, member 6
LDLRAD4 low density lipoprotein receptor class A domain containing 4
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1A microtubule-associated protein 1A
MAP1B microtubule-associated protein 1B
MBD2 methyl-CpG binding domain protein 2
MVB12B multivesicular body subunit 12B
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NUPR1 nuclear protein, transcriptional regulator, 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PACS1 phosphofurin acidic cluster sorting protein 1
PARVA parvin, alpha
PBX2 pre-B-cell leukemia homeobox 2
PDCD1 programmed cell death 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLD1 phospholipase D1, phosphatidylcholine-specific
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PXDC1 PX domain containing 1
RAB11B RAB11B, member RAS oncogene family
RBM5 RNA binding motif protein 5
RCE1 Ras converting CAAX endopeptidase 1
REC8 REC8 meiotic recombination protein
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIF1 replication timing regulatory factor 1
RPLP2 ribosomal protein, large, P2
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SEC23IP SEC23 interacting protein
SEZ6L seizure related 6 homolog (mouse)-like
SH3BP2 SH3-domain binding protein 2
SLC35E2 solute carrier family 35, member E2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNAP25 synaptosomal-associated protein, 25kDa
SPEN spen family transcriptional repressor
ST20 suppressor of tumorigenicity 20
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TAPBP TAP binding protein (tapasin)
TBL2 transducin (beta)-like 2
TIMELESS timeless circadian clock
TIMP3 TIMP metallopeptidase inhibitor 3
TLR2 toll-like receptor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIM36 tripartite motif containing 36
ZC3H7B zinc finger CCCH-type containing 7B
ZNF358 zinc finger protein 358

decreased expression

Symbol Name
ALPK1 alpha-kinase 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BIRC7 baculoviral IAP repeat containing 7
C14ORF93 chromosome 14 open reading frame 93
C4ORF29 chromosome 4 open reading frame 29
C9ORF114 chromosome 9 open reading frame 114
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC85C coiled-coil domain containing 85C
CFAP44 cilia and flagella associated protein 44
CGREF1 cell growth regulator with EF-hand domain 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DENND4C DENN/MADD domain containing 4C
DMC1 DNA meiotic recombinase 1
DPY19L1P1 DPY19L1 pseudogene 1
ERCC2 excision repair cross-complementation group 2
ERCC4 excision repair cross-complementation group 4
EXD3 exonuclease 3'-5' domain containing 3
FBXO5 F-box protein 5
FRS2 fibroblast growth factor receptor substrate 2
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPR27 G protein-coupled receptor 27
GRTP1 growth hormone regulated TBC protein 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BG histone cluster 1, H2bg
HIST1H4F histone cluster 1, H4f
HMGB3P1 high mobility group box 3 pseudogene 1
HOXA4 homeobox A4
HOXC10 homeobox C10
HYI hydroxypyruvate isomerase (putative)
IFT22 intraflagellar transport 22
IL22 interleukin 22
IPP intracisternal A particle-promoted polypeptide
ITFG2 integrin alpha FG-GAP repeat containing 2
KIAA0894 KIAA0894 protein
LHX6 LIM homeobox 6
LIG4 ligase IV, DNA, ATP-dependent
LIN7A lin-7 homolog A (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LRRC37A3 leucine rich repeat containing 37, member A3
MAVS mitochondrial antiviral signaling protein
NLRX1 NLR family member X1
NME5 NME/NM23 family member 5
NOL12 nucleolar protein 12
NPTX1 neuronal pentraxin I
NPY5R neuropeptide Y receptor Y5
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCDHA9 protocadherin alpha 9
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLM polymerase (DNA directed), mu
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PORCN porcupine homolog (Drosophila)
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB30 RAB30, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RFXAP regulatory factor X-associated protein
RND1 Rho family GTPase 1
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SDF2L1 stromal cell-derived factor 2-like 1
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SREK1IP1 SREK1-interacting protein 1
STK19 serine/threonine kinase 19
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TBC1D19 TBC1 domain family, member 19
TBC1D2 TBC1 domain family, member 2
TCP10 t-complex 10
TDRD1 tudor domain containing 1
TEP1 telomerase-associated protein 1
TESC tescalcin
THOP1 thimet oligopeptidase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
UPK3B uroplakin 3B
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR33 WD repeat domain 33
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB6 zinc finger and BTB domain containing 6
ZIC3 Zic family member 3
ZNF204P zinc finger protein 204, pseudogene
ZNF551 zinc finger protein 551
ZNF574 zinc finger protein 574
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF665 zinc finger protein 665
ZNF669 zinc finger protein 669