| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the fenbendazole-4542 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ARTN | artemin |
| ATP9B | ATPase, class II, type 9B |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEP135 | centrosomal protein 135kDa |
| CEP295 | centrosomal protein 295kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CISH | cytokine inducible SH2-containing protein |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CTH | cystathionine gamma-lyase |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DOCK6 | dedicator of cytokinesis 6 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| EDN1 | endothelin 1 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 |
| ESRRG | estrogen-related receptor gamma |
| FAM110B | family with sequence similarity 110, member B |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FERMT2 | fermitin family member 2 |
| FGF5 | fibroblast growth factor 5 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FYB | FYN binding protein |
| GK | glycerol kinase |
| GLIPR1 | GLI pathogenesis-related 1 |
| GPR19 | G protein-coupled receptor 19 |
| GRAMD1C | GRAM domain containing 1C |
| HBE1 | hemoglobin, epsilon 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IFNB1 | interferon, beta 1, fibroblast |
| IL11 | interleukin 11 |
| IL6 | interleukin 6 |
| IL7R | interleukin 7 receptor |
| INO80D | INO80 complex subunit D |
| INSIG1 | insulin induced gene 1 |
| JUND | jun D proto-oncogene |
| KHSRP | KH-type splicing regulatory protein |
| KRT34 | keratin 34, type I |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MON2 | MON2 homolog (S. cerevisiae) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NLE1 | notchless homolog 1 (Drosophila) |
| NRN1 | neuritin 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha |
| PDLIM5 | PDZ and LIM domain 5 |
| PDZD2 | PDZ domain containing 2 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PLK3 | polo-like kinase 3 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R37 | protein phosphatase 1, regulatory subunit 37 |
| PTCH2 | patched 2 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| R3HDM1 | R3H domain containing 1 |
| RBM4 | RNA binding motif protein 4 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RND1 | Rho family GTPase 1 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SMC4 | structural maintenance of chromosomes 4 |
| SNTG1 | syntrophin, gamma 1 |
| SOCS2 | suppressor of cytokine signaling 2 |
| SQLE | squalene epoxidase |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STK24 | serine/threonine kinase 24 |
| TBC1D30 | TBC1 domain family, member 30 |
| TGFB2 | transforming growth factor, beta 2 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TLX3 | T-cell leukemia homeobox 3 |
| TRIB3 | tribbles pseudokinase 3 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF219 | zinc finger protein 219 |
| ZNF268 | zinc finger protein 268 |
| ZNF286A | zinc finger protein 286A |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| APOL6 | apolipoprotein L, 6 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCL9 | B-cell CLL/lymphoma 9 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CA9 | carbonic anhydrase IX |
| CASZ1 | castor zinc finger 1 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CES3 | carboxylesterase 3 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CORO1A | coronin, actin binding protein, 1A |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| EGR2 | early growth response 2 |
| EHF | ets homologous factor |
| FAM131B | family with sequence similarity 131, member B |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FMO4 | flavin containing monooxygenase 4 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| FUZ | fuzzy planar cell polarity protein |
| GAS8 | growth arrest-specific 8 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HAS2 | hyaluronan synthase 2 |
| HELZ | helicase with zinc finger |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3C | histone cluster 1, H3c |
| HIST1H4D | histone cluster 1, H4d |
| HIST2H2BE | histone cluster 2, H2be |
| HOXA1 | homeobox A1 |
| ITPKA | inositol-trisphosphate 3-kinase A |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA1462 | KIAA1462 |
| KLHL28 | kelch-like family member 28 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LOC730101 | uncharacterized LOC730101 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCC | mutated in colorectal cancers |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTA2 | metastasis associated 1 family, member 2 |
| MXRA8 | matrix-remodelling associated 8 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PALMD | palmdelphin |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLAC8 | placenta-specific 8 |
| PLD2 | phospholipase D2 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| RNF122 | ring finger protein 122 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCAMP5 | secretory carrier membrane protein 5 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SPRYD7 | SPRY domain containing 7 |
| TAGLN3 | transgelin 3 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TCTN2 | tectonic family member 2 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRIM25 | tripartite motif containing 25 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TUBA4A | tubulin, alpha 4a |
| TUBB | tubulin, beta class I |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB3 | tubulin, beta 3 class III |
| TUBB4B | tubulin, beta 4B class IVb |
| TUBB6 | tubulin, beta 6 class V |
| USP19 | ubiquitin specific peptidase 19 |
| VASH1 | vasohibin 1 |
| WDR91 | WD repeat domain 91 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZNF205 | zinc finger protein 205 |
| ZNF442 | zinc finger protein 442 |
