fenbufen-2308 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the fenbufen-2308 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAMTSL4 ADAMTS-like 4
ADGRB3 adhesion G protein-coupled receptor B3
AHNAK AHNAK nucleoprotein
AKAP7 A kinase (PRKA) anchor protein 7
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ASB8 ankyrin repeat and SOCS box containing 8
ATF6B activating transcription factor 6 beta
BDKRB2 bradykinin receptor B2
BHLHE41 basic helix-loop-helix family, member e41
BMP15 bone morphogenetic protein 15
C17ORF59 chromosome 17 open reading frame 59
C19ORF66 chromosome 19 open reading frame 66
CARD9 caspase recruitment domain family, member 9
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CNR2 cannabinoid receptor 2 (macrophage)
CSDC2 cold shock domain containing C2, RNA binding
DTNA dystrobrevin, alpha
EDNRA endothelin receptor type A
FAM66D family with sequence similarity 66, member D
FPR2 formyl peptide receptor 2
FRMD1 FERM domain containing 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAR1 GAR1 ribonucleoprotein
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GLB1L galactosidase, beta 1-like
GMPR guanosine monophosphate reductase
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HOXC4 homeobox C4
HSDL2 hydroxysteroid dehydrogenase like 2
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
IDS iduronate 2-sulfatase
IFNA10 interferon, alpha 10
IQCK IQ motif containing K
IRF2BP1 interferon regulatory factor 2 binding protein 1
JUN jun proto-oncogene
KLHL22 kelch-like family member 22
KLK13 kallikrein-related peptidase 13
KMT2A lysine (K)-specific methyltransferase 2A
KREMEN2 kringle containing transmembrane protein 2
LARP6 La ribonucleoprotein domain family, member 6
LINC00216 long intergenic non-protein coding RNA 216
LMTK1 lemur tail kinase 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K5 mitogen-activated protein kinase kinase 5
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MED25 mediator complex subunit 25
MST1L macrophage stimulating 1-like
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NNAT neuronatin
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARVA parvin, alpha
PEAK1 pseudopodium-enriched atypical kinase 1
PHOX2A paired-like homeobox 2a
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
POLM polymerase (DNA directed), mu
PQLC2 PQ loop repeat containing 2
PSG5 pregnancy specific beta-1-glycoprotein 5
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PYY peptide YY
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RARB retinoic acid receptor, beta
RBM5 RNA binding motif protein 5
RELN reelin
RNF126P1 ring finger protein 126 pseudogene 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A13 S100 calcium binding protein A13
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SPDEF SAM pointed domain containing ETS transcription factor
SPRED2 sprouty-related, EVH1 domain containing 2
SRCAP Snf2-related CREBBP activator protein
SRRT serrate, RNA effector molecule
SUN1 Sad1 and UNC84 domain containing 1
TBC1D2 TBC1 domain family, member 2
TEF thyrotrophic embryonic factor
TENM4 teneurin transmembrane protein 4
TFPI2 tissue factor pathway inhibitor 2
TMEM212 transmembrane protein 212
VCX2 variable charge, X-linked 2
VIPR1 vasoactive intestinal peptide receptor 1
WISP3 WNT1 inducible signaling pathway protein 3
XYLT1 xylosyltransferase I
ZNF358 zinc finger protein 358
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
AKTIP AKT interacting protein
ANXA5 annexin A5
ARHGAP10 Rho GTPase activating protein 10
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
AUTS2 autism susceptibility candidate 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAGE B melanoma antigen
BAHCC1 BAH domain and coiled-coil containing 1
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF63 chromosome 11 open reading frame 63
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C3 complement component 3
CCDC176 coiled-coil domain containing 176
CCDC85C coiled-coil domain containing 85C
CDK3 cyclin-dependent kinase 3
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN5 chloride channel, voltage-sensitive 5
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CRABP1 cellular retinoic acid binding protein 1
CRMP1 collapsin response mediator protein 1
CRYGC crystallin, gamma C
CST6 cystatin E/M
DGKD diacylglycerol kinase, delta 130kDa
DMTN dematin actin binding protein
DTX4 deltex 4, E3 ubiquitin ligase
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYSF dysferlin
F2R coagulation factor II (thrombin) receptor
FAM186A family with sequence similarity 186, member A
FBRS fibrosin
FKBP1B FK506 binding protein 1B, 12.6 kDa
FURIN furin (paired basic amino acid cleaving enzyme)
FZD2 frizzled class receptor 2
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GBP2 guanylate binding protein 2, interferon-inducible
GNA13 guanine nucleotide binding protein (G protein), alpha 13
H2AFY2 H2A histone family, member Y2
HDAC2 histone deacetylase 2
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HPS6 Hermansky-Pudlak syndrome 6
IK IK cytokine, down-regulator of HLA II
IP6K2 inositol hexakisphosphate kinase 2
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KEL Kell blood group, metallo-endopeptidase
KIAA0319L KIAA0319-like
KIAA0754 KIAA0754
KLHL25 kelch-like family member 25
LGALS4 lectin, galactoside-binding, soluble, 4
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC390998 ribosomal protein L10 pseudogene
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LRRC42 leucine rich repeat containing 42
MAL mal, T-cell differentiation protein
MEFV Mediterranean fever
MGC12488
MNX1 motor neuron and pancreas homeobox 1
MTA2 metastasis associated 1 family, member 2
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NOL12 nucleolar protein 12
NYNRIN NYN domain and retroviral integrase containing
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OVOL1 ovo-like zinc finger 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
POTEKP POTE ankyrin domain family, member K, pseudogene
PRAF2 PRA1 domain family, member 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
QSER1 glutamine and serine rich 1
RAB33A RAB33A, member RAS oncogene family
RARS arginyl-tRNA synthetase
RBM6 RNA binding motif protein 6
RPH3A rabphilin 3A
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A6 S100 calcium binding protein A6
SCD5 stearoyl-CoA desaturase 5
SETD1A SET domain containing 1A
SIPA1 signal-induced proliferation-associated 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
TBX19 T-box 19
TMC7 transmembrane channel-like 7
TNS2 tensin 2
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
VPS9D1 VPS9 domain containing 1
WDR4 WD repeat domain 4
WDR91 WD repeat domain 91
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF282 zinc finger protein 282
ZNF442 zinc finger protein 442
ZNF446 zinc finger protein 446
ZW10 zw10 kinetochore protein