fenbufen-2346 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the fenbufen-2346 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACVR1B activin A receptor, type IB
AMT aminomethyltransferase
ANKRD55 ankyrin repeat domain 55
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
ARG2 arginase 2
ATAT1 alpha tubulin acetyltransferase 1
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BCL2 B-cell CLL/lymphoma 2
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCDC85B coiled-coil domain containing 85B
CCDC88C coiled-coil domain containing 88C
CD44 CD44 molecule (Indian blood group)
CDC42 cell division cycle 42
CDO1 cysteine dioxygenase type 1
CGA glycoprotein hormones, alpha polypeptide
CIDEC cell death-inducing DFFA-like effector c
CREM cAMP responsive element modulator
CSF1 colony stimulating factor 1 (macrophage)
DAPK3 death-associated protein kinase 3
DGAT1 diacylglycerol O-acyltransferase 1
ELL2 elongation factor, RNA polymerase II, 2
ERP44 endoplasmic reticulum protein 44
ESR1 estrogen receptor 1
FBXO22 F-box protein 22
FGGY FGGY carbohydrate kinase domain containing
FNTB farnesyltransferase, CAAX box, beta
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GSPT1 G1 to S phase transition 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HMOX2 heme oxygenase 2
HNF1A HNF1 homeobox A
HOMER3 homer scaffolding protein 3
INO80D INO80 complex subunit D
IQCK IQ motif containing K
KCNK10 potassium channel, two pore domain subfamily K, member 10
LIMD2 LIM domain containing 2
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBP2 latent transforming growth factor beta binding protein 2
MAP1B microtubule-associated protein 1B
MAP4 microtubule-associated protein 4
MAPK14 mitogen-activated protein kinase 14
MARC1 mitochondrial amidoxime reducing component 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL7A methyltransferase like 7A
MFAP3 microfibrillar-associated protein 3
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLX MLX, MAX dimerization protein
MXD3 MAX dimerization protein 3
MYO1C myosin IC
NDRG2 NDRG family member 2
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPM3 nucleophosmin/nucleoplasmin 3
NRP1 neuropilin 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCNX pecanex homolog (Drosophila)
PCSK6 proprotein convertase subtilisin/kexin type 6
PDLIM5 PDZ and LIM domain 5
PENK proenkephalin
PKNOX1 PBX/knotted 1 homeobox 1
PLEK2 pleckstrin 2
PMP22 peripheral myelin protein 22
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKCZ protein kinase C, zeta
PTCRA pre T-cell antigen receptor alpha
PVR poliovirus receptor
RAD50 RAD50 homolog (S. cerevisiae)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBM19 RNA binding motif protein 19
RPS4Y1 ribosomal protein S4, Y-linked 1
SCLY selenocysteine lyase
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SFT2D2 SFT2 domain containing 2
SFTPB surfactant protein B
SHB Src homology 2 domain containing adaptor protein B
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SOS1 son of sevenless homolog 1 (Drosophila)
SRSF7 serine/arginine-rich splicing factor 7
SSH3 slingshot protein phosphatase 3
TPM2 tropomyosin 2 (beta)
TRD T cell receptor delta locus
TRIM62 tripartite motif containing 62
TTPAL tocopherol (alpha) transfer protein-like
TUBA3C tubulin, alpha 3c
UBA6 ubiquitin-like modifier activating enzyme 6
UBE2I ubiquitin-conjugating enzyme E2I
USB1 U6 snRNA biogenesis 1
VAMP5 vesicle-associated membrane protein 5
VN1R1 vomeronasal 1 receptor 1
ZFPL1 zinc finger protein-like 1
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
AACS acetoacetyl-CoA synthetase
ADGRE2 adhesion G protein-coupled receptor E2
AGO4 argonaute RISC catalytic component 4
ALG12 ALG12, alpha-1,6-mannosyltransferase
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGAP4 Rho GTPase activating protein 4
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATAD5 ATPase family, AAA domain containing 5
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAHCC1 BAH domain and coiled-coil containing 1
BAHD1 bromo adjacent homology domain containing 1
C16ORF59 chromosome 16 open reading frame 59
C1ORF54 chromosome 1 open reading frame 54
C3 complement component 3
CASP7 caspase 7, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD83 CD83 molecule
CDK3 cyclin-dependent kinase 3
CHKB choline kinase beta
CLCN6 chloride channel, voltage-sensitive 6
CLEC7A C-type lectin domain family 7, member A
CRYBB2P1 crystallin, beta B2 pseudogene 1
CUL9 cullin 9
DRAM1 DNA-damage regulated autophagy modulator 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EHD4 EH-domain containing 4
ELP6 elongator acetyltransferase complex subunit 6
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FADS2 fatty acid desaturase 2
FANCC Fanconi anemia, complementation group C
FILIP1L filamin A interacting protein 1-like
FLCN folliculin
FLJ21369 uncharacterized protein FLJ21369
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH2 G patch domain containing 2
GPHN gephyrin
GPR183 G protein-coupled receptor 183
GPR22 G protein-coupled receptor 22
GTF2IRD1 GTF2I repeat domain containing 1
HDAC5 histone deacetylase 5
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BE histone cluster 1, H2be
HIST1H4J histone cluster 1, H4j
HMGB3P1 high mobility group box 3 pseudogene 1
HYAL3 hyaluronoglucosaminidase 3
ICK intestinal cell (MAK-like) kinase
IFT81 intraflagellar transport 81
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITPKB inositol-trisphosphate 3-kinase B
KLHL21 kelch-like family member 21
KLK5 kallikrein-related peptidase 5
LRRC20 leucine rich repeat containing 20
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAGEF1 melanoma antigen family F1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBNL3 muscleblind-like splicing regulator 3
MILR1 mast cell immunoglobulin-like receptor 1
MLPH melanophilin
MYL5 myosin, light chain 5, regulatory
NBEAL2 neurobeachin-like 2
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NIPAL2 NIPA-like domain containing 2
NTSR1 neurotensin receptor 1 (high affinity)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OCEL1 occludin/ELL domain containing 1
PCTP phosphatidylcholine transfer protein
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
QTRT1 queuine tRNA-ribosyltransferase 1
RABL6 RAB, member RAS oncogene family-like 6
RBM47 RNA binding motif protein 47
RCAN3 RCAN family member 3
RHOC ras homolog family member C
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SGMS1 sphingomyelin synthase 1
SHPK sedoheptulokinase
SIPA1 signal-induced proliferation-associated 1
SIRT6 sirtuin 6
STEAP1 six transmembrane epithelial antigen of the prostate 1
SYNJ2BP synaptojanin 2 binding protein
TAOK1 TAO kinase 1
TMEM134 transmembrane protein 134
TMEM8A transmembrane protein 8A
TPK1 thiamin pyrophosphokinase 1
TRIP10 thyroid hormone receptor interactor 10
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF226 zinc finger protein 226
ZNF552 zinc finger protein 552