| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the fenbufen-2346 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACVR1B | activin A receptor, type IB |
| AMT | aminomethyltransferase |
| ANKRD55 | ankyrin repeat domain 55 |
| AP4S1 | adaptor-related protein complex 4, sigma 1 subunit |
| ARG2 | arginase 2 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CCDC85B | coiled-coil domain containing 85B |
| CCDC88C | coiled-coil domain containing 88C |
| CD44 | CD44 molecule (Indian blood group) |
| CDC42 | cell division cycle 42 |
| CDO1 | cysteine dioxygenase type 1 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CIDEC | cell death-inducing DFFA-like effector c |
| CREM | cAMP responsive element modulator |
| CSF1 | colony stimulating factor 1 (macrophage) |
| DAPK3 | death-associated protein kinase 3 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ERP44 | endoplasmic reticulum protein 44 |
| ESR1 | estrogen receptor 1 |
| FBXO22 | F-box protein 22 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FNTB | farnesyltransferase, CAAX box, beta |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GSPT1 | G1 to S phase transition 1 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 |
| HMOX2 | heme oxygenase 2 |
| HNF1A | HNF1 homeobox A |
| HOMER3 | homer scaffolding protein 3 |
| INO80D | INO80 complex subunit D |
| IQCK | IQ motif containing K |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| LIMD2 | LIM domain containing 2 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAP1B | microtubule-associated protein 1B |
| MAP4 | microtubule-associated protein 4 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| METTL7A | methyltransferase like 7A |
| MFAP3 | microfibrillar-associated protein 3 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MLX | MLX, MAX dimerization protein |
| MXD3 | MAX dimerization protein 3 |
| MYO1C | myosin IC |
| NDRG2 | NDRG family member 2 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRP1 | neuropilin 1 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PCNX | pecanex homolog (Drosophila) |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDLIM5 | PDZ and LIM domain 5 |
| PENK | proenkephalin |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLEK2 | pleckstrin 2 |
| PMP22 | peripheral myelin protein 22 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PRKCZ | protein kinase C, zeta |
| PTCRA | pre T-cell antigen receptor alpha |
| PVR | poliovirus receptor |
| RAD50 | RAD50 homolog (S. cerevisiae) |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBM19 | RNA binding motif protein 19 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SCLY | selenocysteine lyase |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SFT2D2 | SFT2 domain containing 2 |
| SFTPB | surfactant protein B |
| SHB | Src homology 2 domain containing adaptor protein B |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SSH3 | slingshot protein phosphatase 3 |
| TPM2 | tropomyosin 2 (beta) |
| TRD | T cell receptor delta locus |
| TRIM62 | tripartite motif containing 62 |
| TTPAL | tocopherol (alpha) transfer protein-like |
| TUBA3C | tubulin, alpha 3c |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| USB1 | U6 snRNA biogenesis 1 |
| VAMP5 | vesicle-associated membrane protein 5 |
| VN1R1 | vomeronasal 1 receptor 1 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| AACS | acetoacetyl-CoA synthetase |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AGO4 | argonaute RISC catalytic component 4 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C3 | complement component 3 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CD83 | CD83 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CHKB | choline kinase beta |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLEC7A | C-type lectin domain family 7, member A |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CUL9 | cullin 9 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EHD4 | EH-domain containing 4 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FADS2 | fatty acid desaturase 2 |
| FANCC | Fanconi anemia, complementation group C |
| FILIP1L | filamin A interacting protein 1-like |
| FLCN | folliculin |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPATCH2 | G patch domain containing 2 |
| GPHN | gephyrin |
| GPR183 | G protein-coupled receptor 183 |
| GPR22 | G protein-coupled receptor 22 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| HDAC5 | histone deacetylase 5 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H4J | histone cluster 1, H4j |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ICK | intestinal cell (MAK-like) kinase |
| IFT81 | intraflagellar transport 81 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KLHL21 | kelch-like family member 21 |
| KLK5 | kallikrein-related peptidase 5 |
| LRRC20 | leucine rich repeat containing 20 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAGEF1 | melanoma antigen family F1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MLPH | melanophilin |
| MYL5 | myosin, light chain 5, regulatory |
| NBEAL2 | neurobeachin-like 2 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| NIPAL2 | NIPA-like domain containing 2 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OCEL1 | occludin/ELL domain containing 1 |
| PCTP | phosphatidylcholine transfer protein |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RBM47 | RNA binding motif protein 47 |
| RCAN3 | RCAN family member 3 |
| RHOC | ras homolog family member C |
| SETD1A | SET domain containing 1A |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGMS1 | sphingomyelin synthase 1 |
| SHPK | sedoheptulokinase |
| SIPA1 | signal-induced proliferation-associated 1 |
| SIRT6 | sirtuin 6 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| SYNJ2BP | synaptojanin 2 binding protein |
| TAOK1 | TAO kinase 1 |
| TMEM134 | transmembrane protein 134 |
| TMEM8A | transmembrane protein 8A |
| TPK1 | thiamin pyrophosphokinase 1 |
| TRIP10 | thyroid hormone receptor interactor 10 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF226 | zinc finger protein 226 |
| ZNF552 | zinc finger protein 552 |