| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the fenbufen-3618 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADAMDEC1 | ADAM-like, decysin 1 |
| ADORA1 | adenosine A1 receptor |
| AMOT | angiomotin |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP10B | ATPase, class V, type 10B |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| AVPR1B | arginine vasopressin receptor 1B |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CACNG3 | calcium channel, voltage-dependent, gamma subunit 3 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CAPZB | capping protein (actin filament) muscle Z-line, beta |
| CARD10 | caspase recruitment domain family, member 10 |
| CCDC40 | coiled-coil domain containing 40 |
| CD82 | CD82 molecule |
| CD96 | CD96 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| COL21A1 | collagen, type XXI, alpha 1 |
| CRMP1 | collapsin response mediator protein 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) |
| CYP2C19 | cytochrome P450, family 2, subfamily C, polypeptide 19 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DKFZP434C153 | DKFZP434C153 protein |
| ECE1 | endothelin converting enzyme 1 |
| EDN1 | endothelin 1 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| EXPH5 | exophilin 5 |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FBN1 | fibrillin 1 |
| FGF18 | fibroblast growth factor 18 |
| FLOT1 | flotillin 1 |
| FN1 | fibronectin 1 |
| FXYD7 | FXYD domain containing ion transport regulator 7 |
| GAST | gastrin |
| GM2A | GM2 ganglioside activator |
| HBB | hemoglobin, beta |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HEMK1 | HemK methyltransferase family member 1 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IL1RAP | interleukin 1 receptor accessory protein |
| IL1RN | interleukin 1 receptor antagonist |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| KDM5A | lysine (K)-specific demethylase 5A |
| KLHL22 | kelch-like family member 22 |
| KRT17 | keratin 17, type I |
| LIMK1 | LIM domain kinase 1 |
| LOC157562 | uncharacterized LOC157562 |
| LRRC48 | leucine rich repeat containing 48 |
| LTA | lymphotoxin alpha |
| LYZL6 | lysozyme-like 6 |
| MED16 | mediator complex subunit 16 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NIPAL3 | NIPA-like domain containing 3 |
| NPR2 | natriuretic peptide receptor 2 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| OR7A17 | olfactory receptor, family 7, subfamily A, member 17 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDE10A | phosphodiesterase 10A |
| PLXDC1 | plexin domain containing 1 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RAB3B | RAB3B, member RAS oncogene family |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SERHL2 | serine hydrolase-like 2 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TLR1 | toll-like receptor 1 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| VPRBP | Vpr (HIV-1) binding protein |
| WDR62 | WD repeat domain 62 |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| XAF1 | XIAP associated factor 1 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZG16 | zymogen granule protein 16 |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| AIRE | autoimmune regulator |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| AXIN1 | axin 1 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BMP10 | bone morphogenetic protein 10 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC9 | coiled-coil domain containing 9 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CPNE7 | copine VII |
| CTRL | chymotrypsin-like |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DOK2 | docking protein 2, 56kDa |
| DYSF | dysferlin |
| EFNA3 | ephrin-A3 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ERCC6 | excision repair cross-complementation group 6 |
| FAM131A | family with sequence similarity 131, member A |
| FAM155A | family with sequence similarity 155, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| GFI1 | growth factor independent 1 transcription repressor |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR27 | G protein-coupled receptor 27 |
| GRPR | gastrin-releasing peptide receptor |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H4F | histone cluster 1, H4f |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXC4 | homeobox C4 |
| HOXC5 | homeobox C5 |
| HOXC8 | homeobox C8 |
| IFNA17 | interferon, alpha 17 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA1107 | KIAA1107 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRT9 | keratin 9, type I |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LOXL3 | lysyl oxidase-like 3 |
| LRRC49 | leucine rich repeat containing 49 |
| MBTD1 | mbt domain containing 1 |
| MED9 | mediator complex subunit 9 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MOB3B | MOB kinase activator 3B |
| NDE1 | nudE neurodevelopment protein 1 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| ONECUT2 | one cut homeobox 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PICK1 | protein interacting with PRKCA 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| POLL | polymerase (DNA directed), lambda |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RECQL4 | RecQ protein-like 4 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF208 | ring finger protein 208 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLN | sarcolipin |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STIM1 | stromal interaction molecule 1 |
| SYT17 | synaptotagmin XVII |
| TBC1D19 | TBC1 domain family, member 19 |
| TBKBP1 | TBK1 binding protein 1 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TEP1 | telomerase-associated protein 1 |
| TMEM19 | transmembrane protein 19 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TUBA3C | tubulin, alpha 3c |
| UBTD1 | ubiquitin domain containing 1 |
| VASH2 | vasohibin 2 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFP37 | ZFP37 zinc finger protein |
| ZNF350 | zinc finger protein 350 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |