| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the fenbufen-3721 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACPP | acid phosphatase, prostate |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| AFF1 | AF4/FMR2 family, member 1 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| APOA4 | apolipoprotein A-IV |
| APP | amyloid beta (A4) precursor protein |
| ARTN | artemin |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATF6B | activating transcription factor 6 beta |
| BAIAP2 | BAI1-associated protein 2 |
| BBC3 | BCL2 binding component 3 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CCDC121 | coiled-coil domain containing 121 |
| CDC25C | cell division cycle 25C |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CEL | carboxyl ester lipase |
| CES1 | carboxylesterase 1 |
| CFHR5 | complement factor H-related 5 |
| CLEC4M | C-type lectin domain family 4, member M |
| CRAT | carnitine O-acetyltransferase |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP1 | dual specificity phosphatase 1 |
| ENG | endoglin |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FAM212B | family with sequence similarity 212, member B |
| FBXO21 | F-box protein 21 |
| FGB | fibrinogen beta chain |
| GATA2 | GATA binding protein 2 |
| GGT1 | gamma-glutamyltransferase 1 |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GPR19 | G protein-coupled receptor 19 |
| HCP5 | HLA complex P5 (non-protein coding) |
| HDAC6 | histone deacetylase 6 |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H3F | histone cluster 1, H3f |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IL32 | interleukin 32 |
| IRF4 | interferon regulatory factor 4 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIRREL | kin of IRRE like (Drosophila) |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LAT2 | linker for activation of T cells family, member 2 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LMX1B | LIM homeobox transcription factor 1, beta |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MPZ | myelin protein zero |
| MVD | mevalonate (diphospho) decarboxylase |
| NPHP4 | nephronophthisis 4 |
| NRP2 | neuropilin 2 |
| NUP214 | nucleoporin 214kDa |
| OBSL1 | obscurin-like 1 |
| OVOL1 | ovo-like zinc finger 1 |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDE8B | phosphodiesterase 8B |
| PGP | phosphoglycolate phosphatase |
| PHOX2B | paired-like homeobox 2b |
| PML | promyelocytic leukemia |
| PRDX2 | peroxiredoxin 2 |
| PRMT2IP | PRMT2 interacting protein |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PURA | purine-rich element binding protein A |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RAD51 | RAD51 recombinase |
| RGS17 | regulator of G-protein signaling 17 |
| RNF17 | ring finger protein 17 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase |
| S100A12 | S100 calcium binding protein A12 |
| SLCO1A2 | solute carrier organic anion transporter family, member 1A2 |
| SPO11 | SPO11 meiotic protein covalently bound to DSB |
| TAAR3 | trace amine associated receptor 3 (gene/pseudogene) |
| TBX1 | T-box 1 |
| TRAF4 | TNF receptor-associated factor 4 |
| TRH | thyrotropin-releasing hormone |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| WIZ | widely interspaced zinc finger motifs |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| AFF4 | AF4/FMR2 family, member 4 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AK5 | adenylate kinase 5 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BMP4 | bone morphogenetic protein 4 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC176 | coiled-coil domain containing 176 |
| CCNJL | cyclin J-like |
| CEP295 | centrosomal protein 295kDa |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLSTN3 | calsyntenin 3 |
| COBL | cordon-bleu WH2 repeat protein |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DAGLA | diacylglycerol lipase, alpha |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNM3 | dynamin 3 |
| DOCK1 | dedicator of cytokinesis 1 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EFNB1 | ephrin-B1 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EML4 | echinoderm microtubule associated protein like 4 |
| FAM120C | family with sequence similarity 120C |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| GAN | gigaxonin |
| GK3P | glycerol kinase 3 pseudogene |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR1 | G protein-coupled receptor 1 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GTPBP2 | GTP binding protein 2 |
| HELZ | helicase with zinc finger |
| HIST1H1D | histone cluster 1, H1d |
| HOXB9 | homeobox B9 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLF3 | Kruppel-like factor 3 (basic) |
| LOC100127972 | uncharacterized LOC100127972 |
| LOC257152 | uncharacterized LOC257152 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRRC6 | leucine rich repeat containing 6 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OLFML2A | olfactomedin-like 2A |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PODXL2 | podocalyxin-like 2 |
| PRPF39 | pre-mRNA processing factor 39 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RIN1 | Ras and Rab interactor 1 |
| ROM1 | retinal outer segment membrane protein 1 |
| SCEL | sciellin |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SETD1A | SET domain containing 1A |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SPAG4 | sperm associated antigen 4 |
| SPIDR | scaffolding protein involved in DNA repair |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STRN | striatin, calmodulin binding protein |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| THBS3 | thrombospondin 3 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TUBA3C | tubulin, alpha 3c |
| TUBB2B | tubulin, beta 2B class IIb |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF215 | zinc finger protein 215 |
| ZNF286A | zinc finger protein 286A |
| ZNF573 | zinc finger protein 573 |
| ZNF667 | zinc finger protein 667 |
| ZNF749 | zinc finger protein 749 |