fendiline-1573 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the fendiline-1573 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ASXL1 additional sex combs like transcriptional regulator 1
BATF basic leucine zipper transcription factor, ATF-like
BIRC5 baculoviral IAP repeat containing 5
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C2CD2L C2CD2-like
CAST calpastatin
CCDC64 coiled-coil domain containing 64
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CD84 CD84 molecule
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CHKA choline kinase alpha
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CYLD cylindromatosis (turban tumor syndrome)
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ELMO2 engulfment and cell motility 2
EPOR erythropoietin receptor
ERCC8 excision repair cross-complementation group 8
F11R F11 receptor
FKBP9 FK506 binding protein 9, 63 kDa
FOXA2 forkhead box A2
FPGS folylpolyglutamate synthase
GCH1 GTP cyclohydrolase 1
GOSR2 golgi SNAP receptor complex member 2
GSK3A glycogen synthase kinase 3 alpha
HDAC7 histone deacetylase 7
HLA-E major histocompatibility complex, class I, E
HNF1A HNF1 homeobox A
HYAL2 hyaluronoglucosaminidase 2
IL1RN interleukin 1 receptor antagonist
JRK Jrk homolog (mouse)
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIF3C kinesin family member 3C
KRT38 keratin 38, type I
LHB luteinizing hormone beta polypeptide
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LRP6 low density lipoprotein receptor-related protein 6
MALT1 MALT1 paracaspase
MAML3 mastermind-like 3 (Drosophila)
MBD3 methyl-CpG binding domain protein 3
MDC1 mediator of DNA-damage checkpoint 1
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MLX MLX, MAX dimerization protein
MPHOSPH9 M-phase phosphoprotein 9
MSH3 mutS homolog 3
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MTA1 metastasis associated 1
MVK mevalonate kinase
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYOF myoferlin
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCOA3 nuclear receptor coactivator 3
NDRG3 NDRG family member 3
NEFH neurofilament, heavy polypeptide
NGLY1 N-glycanase 1
NOP16 NOP16 nucleolar protein
NR4A1 nuclear receptor subfamily 4, group A, member 1
PHOX2B paired-like homeobox 2b
PICK1 protein interacting with PRKCA 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PORCN porcupine homolog (Drosophila)
PRRC2B proline-rich coiled-coil 2B
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBM5 RNA binding motif protein 5
RPS11 ribosomal protein S11
SEC24A SEC24 family member A
SEC31B SEC31 homolog B (S. cerevisiae)
SGK1 serum/glucocorticoid regulated kinase 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIDT2 SID1 transmembrane family, member 2
SIRT6 sirtuin 6
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMG9 SMG9 nonsense mediated mRNA decay factor
SPATA5L1 spermatogenesis associated 5-like 1
SPRYD7 SPRY domain containing 7
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
TCTN1 tectonic family member 1
TCTN2 tectonic family member 2
TUBD1 tubulin, delta 1
USF2 upstream transcription factor 2, c-fos interacting
VENTX VENT homeobox
VILL villin-like
WDR48 WD repeat domain 48
ZHX3 zinc fingers and homeoboxes 3
ZNF451 zinc finger protein 451
ZNF473 zinc finger protein 473

decreased expression

Symbol Name
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ALS2CL ALS2 C-terminal like
APOC2 apolipoprotein C-II
BCOR BCL6 corepressor
C1ORF112 chromosome 1 open reading frame 112
CASP8AP2 caspase 8 associated protein 2
CD3EAP CD3e molecule, epsilon associated protein
CD69 CD69 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEP170B centrosomal protein 170B
CEP85 centrosomal protein 85kDa
CLDN15 claudin 15
CPOX coproporphyrinogen oxidase
CRTAP cartilage associated protein
CTCF CCCTC-binding factor (zinc finger protein)
CTDNEP1 CTD nuclear envelope phosphatase 1
DNAAF2 dynein, axonemal, assembly factor 2
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DSN1 DSN1, MIS12 kinetochore complex component
EDC4 enhancer of mRNA decapping 4
EGR1 early growth response 1
ELP4 elongator acetyltransferase complex subunit 4
FAM222B family with sequence similarity 222, member B
FAM3C family with sequence similarity 3, member C
FKTN fukutin
GATAD2A GATA zinc finger domain containing 2A
GBAP1 glucosidase, beta, acid pseudogene 1
GCLM glutamate-cysteine ligase, modifier subunit
GPATCH2 G patch domain containing 2
GSTCD glutathione S-transferase, C-terminal domain containing
GTPBP3 GTP binding protein 3 (mitochondrial)
HMG20A high mobility group 20A
HPS5 Hermansky-Pudlak syndrome 5
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
KCTD15 potassium channel tetramerization domain containing 15
KIAA0753 KIAA0753
KPNA4 karyopherin alpha 4 (importin alpha 3)
LACTB2 lactamase, beta 2
MACROD1 MACRO domain containing 1
MAGOHB mago-nashi homolog B (Drosophila)
MAPK10 mitogen-activated protein kinase 10
MATK megakaryocyte-associated tyrosine kinase
MCM10 minichromosome maintenance complex component 10
MEPCE methylphosphate capping enzyme
MEX3C mex-3 RNA binding family member C
MFSD12 major facilitator superfamily domain containing 12
MPV17 MpV17 mitochondrial inner membrane protein
MUTYH mutY homolog
MYL12B myosin, light chain 12B, regulatory
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NAP1L4 nucleosome assembly protein 1-like 4
NCOA4 nuclear receptor coactivator 4
NHEJ1 nonhomologous end-joining factor 1
NUCB2 nucleobindin 2
PAK1IP1 PAK1 interacting protein 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PEX26 peroxisomal biogenesis factor 26
PHLDA2 pleckstrin homology-like domain, family A, member 2
PISD phosphatidylserine decarboxylase
PRMT3 protein arginine methyltransferase 3
PRPF3 pre-mRNA processing factor 3
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PUS7 pseudouridylate synthase 7 (putative)
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RBM4B RNA binding motif protein 4B
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SDCCAG3 serologically defined colon cancer antigen 3
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLMO2 slowmo homolog 2 (Drosophila)
SPON2 spondin 2, extracellular matrix protein
STAR steroidogenic acute regulatory protein
STRA13 stimulated by retinoic acid 13
THAP11 THAP domain containing 11
TIPIN TIMELESS interacting protein
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMEM14A transmembrane protein 14A
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM45A transmembrane protein 45A
TOP2B topoisomerase (DNA) II beta 180kDa
TRHDE thyrotropin-releasing hormone degrading enzyme
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
TTF2 transcription termination factor, RNA polymerase II
TWF2 twinfilin actin binding protein 2
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
USP8 ubiquitin specific peptidase 8
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
WDR82 WD repeat domain 82
WDYHV1 WDYHV motif containing 1
ZEB2 zinc finger E-box binding homeobox 2