| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the fendiline-7188 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AK2 | adenylate kinase 2 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CD44 | CD44 molecule (Indian blood group) |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| DCTN1 | dynactin 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4H | histone cluster 1, H4h |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HRK | harakiri, BCL2 interacting protein |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| IER2 | immediate early response 2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| IRF9 | interferon regulatory factor 9 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JUN | jun proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARS | methionyl-tRNA synthetase |
| MIR22HG | MIR22 host gene |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MVD | mevalonate (diphospho) decarboxylase |
| NBR1 | neighbor of BRCA1 gene 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RCAN1 | regulator of calcineurin 1 |
| RGS2 | regulator of G-protein signaling 2 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TRIB1 | tribbles pseudokinase 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TSC22D3 | TSC22 domain family, member 3 |
| VEGFA | vascular endothelial growth factor A |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZNF165 | zinc finger protein 165 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ABHD10 | abhydrolase domain containing 10 |
| ACTR5 | ARP5 actin-related protein 5 homolog (yeast) |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ARRB2 | arrestin, beta 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B3GNT1 | |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BCORL1 | BCL6 corepressor-like 1 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CA2 | carbonic anhydrase II |
| CASKIN2 | CASK interacting protein 2 |
| CBR4 | carbonyl reductase 4 |
| CCS | copper chaperone for superoxide dismutase |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHMP6 | charged multivesicular body protein 6 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| DCLRE1A | DNA cross-link repair 1A |
| DEAF1 | DEAF1 transcription factor |
| DSPP | dentin sialophosphoprotein |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EPN3 | epsin 3 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM63A | family with sequence similarity 63, member A |
| FBXL14 | F-box and leucine-rich repeat protein 14 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FUZ | fuzzy planar cell polarity protein |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GLI3 | GLI family zinc finger 3 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HOXC11 | homeobox C11 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| IPO8 | importin 8 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA0125 | KIAA0125 |
| KLHL26 | kelch-like family member 26 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC20 | leucine rich repeat containing 20 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAP6D1 | MAP6 domain containing 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MED15 | mediator complex subunit 15 |
| MMP9 | matrix metallopeptidase 9 |
| NARFL | nuclear prelamin A recognition factor-like |
| NCAM2 | neural cell adhesion molecule 2 |
| NES | nestin |
| OLFML3 | olfactomedin-like 3 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PAQR3 | progestin and adipoQ receptor family member III |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRKCD | protein kinase C, delta |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB23 | RAB23, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RBL1 | retinoblastoma-like 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| SACS | sacsin molecular chaperone |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SH2D4A | SH2 domain containing 4A |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| STK16 | serine/threonine kinase 16 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THOP1 | thimet oligopeptidase 1 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM180 | transmembrane protein 180 |
| TNS2 | tensin 2 |
| TRIM66 | tripartite motif containing 66 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| USB1 | U6 snRNA biogenesis 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| XYLT2 | xylosyltransferase II |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNF480 | zinc finger protein 480 |
| ZNF574 | zinc finger protein 574 |
| ZNF586 | zinc finger protein 586 |
| ZNF692 | zinc finger protein 692 |
