fenoprofen-2553 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the fenoprofen-2553 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARC activity-regulated cytoskeleton-associated protein
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARNT aryl hydrocarbon receptor nuclear translocator
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
BIN1 bridging integrator 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CALCR calcitonin receptor
CBR3 carbonyl reductase 3
CCR4 chemokine (C-C motif) receptor 4
CD52 CD52 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CLCN4 chloride channel, voltage-sensitive 4
CLDN17 claudin 17
CRAT carnitine O-acetyltransferase
CSNK1E casein kinase 1, epsilon
DDR1 discoidin domain receptor tyrosine kinase 1
DHRS12 dehydrogenase/reductase (SDR family) member 12
ELF5 E74-like factor 5 (ets domain transcription factor)
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EPYC epiphycan
ERBB2 erb-b2 receptor tyrosine kinase 2
FGL1 fibrinogen-like 1
FHL1 four and a half LIM domains 1
FLJ11292
FLT1 fms-related tyrosine kinase 1
FOXD1 forkhead box D1
G6PC2 glucose-6-phosphatase, catalytic, 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GJA4 gap junction protein, alpha 4, 37kDa
GNAS GNAS complex locus
GRIP2 glutamate receptor interacting protein 2
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HAB1 B1 for mucin
HNF1B HNF1 homeobox B
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IFITM1 interferon induced transmembrane protein 1
INO80D INO80 complex subunit D
INPP5J inositol polyphosphate-5-phosphatase J
IRF4 interferon regulatory factor 4
ITGB5 integrin, beta 5
IZUMO4 IZUMO family member 4
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLF12 Kruppel-like factor 12
KLRB1 killer cell lectin-like receptor subfamily B, member 1
LOX lysyl oxidase
LZTS3 leucine zipper, putative tumor suppressor family member 3
MFAP3L microfibrillar-associated protein 3-like
MIA2 melanoma inhibitory activity 2
MID1 midline 1
MRC2 mannose receptor, C type 2
MTSS1 metastasis suppressor 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOTCH3 notch 3
NR0B1 nuclear receptor subfamily 0, group B, member 1
PDE12 phosphodiesterase 12
PDGFB platelet-derived growth factor beta polypeptide
PKD2L2 polycystic kidney disease 2-like 2
PKLR pyruvate kinase, liver and RBC
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PP14571 uncharacterized LOC100130449
PRAMEF11 PRAME family member 11
PRB1 proline-rich protein BstNI subfamily 1
PRKY protein kinase, Y-linked, pseudogene
PRM2 protamine 2
PRSS3 protease, serine, 3
PYY peptide YY
RAB40B RAB40B, member RAS oncogene family
RASAL2 RAS protein activator like 2
RNF39 ring finger protein 39
RPL13 ribosomal protein L13
SCN5A sodium channel, voltage gated, type V alpha subunit
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SPN sialophorin
STAB2 stabilin 2
SYT5 synaptotagmin V
THSD7A thrombospondin, type I, domain containing 7A
TMEM59L transmembrane protein 59-like
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
USP29 ubiquitin specific peptidase 29
ZNF407 zinc finger protein 407
ZNF484 zinc finger protein 484
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADGRE2 adhesion G protein-coupled receptor E2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAT1 alpha tubulin acetyltransferase 1
BCORL1 BCL6 corepressor-like 1
BTBD3 BTB (POZ) domain containing 3
C11ORF30 chromosome 11 open reading frame 30
C11ORF68 chromosome 11 open reading frame 68
C3 complement component 3
CAMKMT calmodulin-lysine N-methyltransferase
CBX8 chromobox homolog 8
CCDC176 coiled-coil domain containing 176
CCNT1 cyclin T1
CDC37L1 cell division cycle 37-like 1
CEP97 centrosomal protein 97kDa
CHML choroideremia-like (Rab escort protein 2)
CIR1 corepressor interacting with RBPJ, 1
CLSPN claspin
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CORT cortistatin
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRYGC crystallin, gamma C
CTSO cathepsin O
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
ERO1LB ERO1-like beta (S. cerevisiae)
ETV6 ets variant 6
FGF6 fibroblast growth factor 6
FHIT fragile histidine triad
FOXN2 forkhead box N2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GSTCD glutathione S-transferase, C-terminal domain containing
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIST1H1E histone cluster 1, H1e
HIST1H1T histone cluster 1, H1t
HIST1H2AC histone cluster 1, H2ac
HIST1H2BI histone cluster 1, H2bi
HSPA1L heat shock 70kDa protein 1-like
IGKV3-20 immunoglobulin kappa variable 3-20
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ISG15 ISG15 ubiquitin-like modifier
ITGA10 integrin, alpha 10
JMJD4 jumonji domain containing 4
KDM7A lysine (K)-specific demethylase 7A
KIAA1024 KIAA1024
KIAA1456 KIAA1456
KLHL36 kelch-like family member 36
LIN7A lin-7 homolog A (C. elegans)
LINC00260 long intergenic non-protein coding RNA 260
METTL21B methyltransferase like 21B
MMP9 matrix metallopeptidase 9
MUM1 melanoma associated antigen (mutated) 1
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NPFFR1 neuropeptide FF receptor 1
NPM3 nucleophosmin/nucleoplasmin 3
NRGN neurogranin (protein kinase C substrate, RC3)
NT5E 5'-nucleotidase, ecto (CD73)
PARP16 poly (ADP-ribose) polymerase family, member 16
PCNXL4 pecanex-like 4 (Drosophila)
PGPEP1 pyroglutamyl-peptidase I
PHC1 polyhomeotic homolog 1 (Drosophila)
PITX2 paired-like homeodomain 2
PLA2G15 phospholipase A2, group XV
POM121 POM121 transmembrane nucleoporin
POMZP3 POM121 and ZP3 fusion
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRICKLE3 prickle homolog 3 (Drosophila)
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PWAR5 Prader Willi/Angelman region RNA 5
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF122 ring finger protein 122
SKI SKI proto-oncogene
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNX15 sorting nexin 15
SOX12 SRY (sex determining region Y)-box 12
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBCCD1 TBCC domain containing 1
TEP1 telomerase-associated protein 1
THEM6 thioesterase superfamily member 6
TMEM242 transmembrane protein 242
TNNT1 troponin T type 1 (skeletal, slow)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPYL2 TSPY-like 2
TTBK2 tau tubulin kinase 2
UBXN6 UBX domain protein 6
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
XAB2 XPA binding protein 2
ZC2HC1A zinc finger, C2HC-type containing 1A
ZNF675 zinc finger protein 675
ZNF696 zinc finger protein 696
ZNF787 zinc finger protein 787
ZSCAN26 zinc finger and SCAN domain containing 26