fenoterol-2378 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the fenoterol-2378 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDOB aldolase B, fructose-bisphosphate
APP amyloid beta (A4) precursor protein
AREG amphiregulin
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARL4C ADP-ribosylation factor-like 4C
ARRB2 arrestin, beta 2
AXL AXL receptor tyrosine kinase
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BTF3P11 basic transcription factor 3 pseudogene 11
CA9 carbonic anhydrase IX
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CCNG2 cyclin G2
CD38 CD38 molecule
CD86 CD86 molecule
CDC25C cell division cycle 25C
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFP complement factor properdin
CHN2 chimerin 2
CREM cAMP responsive element modulator
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CTNS cystinosin, lysosomal cystine transporter
CUL4B cullin 4B
DOCK4 dedicator of cytokinesis 4
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FLRT2 fibronectin leucine rich transmembrane protein 2
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GAS7 growth arrest-specific 7
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPR137 G protein-coupled receptor 137
GPR183 G protein-coupled receptor 183
GRIK5 glutamate receptor, ionotropic, kainate 5
HIST1H2BD histone cluster 1, H2bd
HLA-DRA major histocompatibility complex, class II, DR alpha
HPSE heparanase
HYAL3 hyaluronoglucosaminidase 3
ICOSLG inducible T-cell co-stimulator ligand
IL10RA interleukin 10 receptor, alpha
IL11 interleukin 11
IL1RN interleukin 1 receptor antagonist
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
KDM7A lysine (K)-specific demethylase 7A
KIF13B kinesin family member 13B
KIF3C kinesin family member 3C
KYNU kynureninase
LIMS2 LIM and senescent cell antigen-like domains 2
LPAR2 lysophosphatidic acid receptor 2
LPAR6 lysophosphatidic acid receptor 6
LPIN2 lipin 2
METTL7A methyltransferase like 7A
MKL2 MKL/myocardin-like 2
MX2 MX dynamin-like GTPase 2
MYO1B myosin IB
NEK3 NIMA-related kinase 3
NPEPL1 aminopeptidase-like 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PDLIM7 PDZ and LIM domain 7 (enigma)
PECAM1 platelet/endothelial cell adhesion molecule 1
PIPOX pipecolic acid oxidase
PLA2G2E phospholipase A2, group IIE
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLEC plectin
PLSCR1 phospholipid scramblase 1
PLSCR3 phospholipid scramblase 3
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PTPRB protein tyrosine phosphatase, receptor type, B
RASAL1 RAS protein activator like 1 (GAP1 like)
REPS2 RALBP1 associated Eps domain containing 2
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RUNX1 runt-related transcription factor 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC2 syndecan 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STS steroid sulfatase (microsomal), isozyme S
TBC1D17 TBC1 domain family, member 17
TBC1D19 TBC1 domain family, member 19
TCF3 transcription factor 3
TCTN1 tectonic family member 1
THBS1 thrombospondin 1
TLE3 transducin-like enhancer of split 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRBC1 T cell receptor beta constant 1
TREM1 triggering receptor expressed on myeloid cells 1
TYMP thymidine phosphorylase
VCX2 variable charge, X-linked 2
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZNF177 zinc finger protein 177

decreased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRA3 adhesion G protein-coupled receptor A3
ALS2CL ALS2 C-terminal like
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA2P2 annexin A2 pseudogene 2
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
BAHCC1 BAH domain and coiled-coil containing 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
BRD9 bromodomain containing 9
C10ORF2 chromosome 10 open reading frame 2
CA2 carbonic anhydrase II
CAPN5 calpain 5
CBS cystathionine-beta-synthase
CCDC6 coiled-coil domain containing 6
CCDC85C coiled-coil domain containing 85C
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDK6 cyclin-dependent kinase 6
CDR2L cerebellar degeneration-related protein 2-like
CECR5 cat eye syndrome chromosome region, candidate 5
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CTH cystathionine gamma-lyase
DDN dendrin
DENND2D DENN/MADD domain containing 2D
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ENDOG endonuclease G
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
EXOSC5 exosome component 5
FAM184A family with sequence similarity 184, member A
FKBP14 FK506 binding protein 14, 22 kDa
FLT3 fms-related tyrosine kinase 3
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HMGA2 high mobility group AT-hook 2
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOPX HOP homeobox
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IFRD2 interferon-related developmental regulator 2
IPO4 importin 4
ITPKB inositol-trisphosphate 3-kinase B
KIAA1024 KIAA1024
LAMP5 lysosomal-associated membrane protein family, member 5
LRP3 low density lipoprotein receptor-related protein 3
LRRC37A3 leucine rich repeat containing 37, member A3
METRN meteorin, glial cell differentiation regulator
METTL8 methyltransferase like 8
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MTA2 metastasis associated 1 family, member 2
NAT10 N-acetyltransferase 10 (GCN5-related)
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NFE2L3 nuclear factor, erythroid 2-like 3
NIP7 NIP7, nucleolar pre-rRNA processing protein
NOL6 nucleolar protein 6 (RNA-associated)
PFKM phosphofructokinase, muscle
PLXND1 plexin D1
POLM polymerase (DNA directed), mu
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKG2 protein kinase, cGMP-dependent, type II
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PUS7 pseudouridylate synthase 7 (putative)
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB3A RAB3A, member RAS oncogene family
RABEPK Rab9 effector protein with kelch motifs
RPA4 replication protein A4, 30kDa
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SCD5 stearoyl-CoA desaturase 5
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SETD6 SET domain containing 6
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC12A9 solute carrier family 12, member 9
SLC22A14 solute carrier family 22, member 14
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPON2 spondin 2, extracellular matrix protein
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STK25 serine/threonine kinase 25
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TERT telomerase reverse transcriptase
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNRC6B trinucleotide repeat containing 6B
UBQLN4 ubiquilin 4
UNC13B unc-13 homolog B (C. elegans)
WWC2 WW and C2 domain containing 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF253 zinc finger protein 253
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF428 zinc finger protein 428
ZNF551 zinc finger protein 551
ZNF696 zinc finger protein 696