fenoterol-5432 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the fenoterol-5432 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ACTN2 actinin, alpha 2
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
AIF1 allograft inflammatory factor 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AMPD3 adenosine monophosphate deaminase 3
ANGPTL2 angiopoietin-like 2
ASIC1 acid sensing (proton gated) ion channel 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL2A1 BCL2-related protein A1
BICC1 BicC family RNA binding protein 1
BMP1 bone morphogenetic protein 1
C11ORF63 chromosome 11 open reading frame 63
C5AR2 complement component 5a receptor 2
C9ORF156 chromosome 9 open reading frame 156
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CD86 CD86 molecule
CDH18 cadherin 18, type 2
CDK14 cyclin-dependent kinase 14
CDK18 cyclin-dependent kinase 18
COL14A1 collagen, type XIV, alpha 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DNALI1 dynein, axonemal, light intermediate chain 1
DOPEY2 dopey family member 2
DTNA dystrobrevin, alpha
ECE1 endothelin converting enzyme 1
EGFR epidermal growth factor receptor
ETV6 ets variant 6
FGF1 fibroblast growth factor 1 (acidic)
FLT1 fms-related tyrosine kinase 1
FOXH1 forkhead box H1
FRAS1 Fraser extracellular matrix complex subunit 1
GJB3 gap junction protein, beta 3, 31kDa
GM2A GM2 ganglioside activator
GPC3 glypican 3
GSTM5 glutathione S-transferase mu 5
GYPB glycophorin B (MNS blood group)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HDAC11 histone deacetylase 11
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IL1RN interleukin 1 receptor antagonist
INE1 inactivation escape 1 (non-protein coding)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
LOX lysyl oxidase
LPCAT3 lysophosphatidylcholine acyltransferase 3
LY75 lymphocyte antigen 75
MAB21L2 mab-21-like 2 (C. elegans)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MON2 MON2 homolog (S. cerevisiae)
MZF1 myeloid zinc finger 1
NEK9 NIMA-related kinase 9
NOX3 NADPH oxidase 3
NPFF neuropeptide FF-amide peptide precursor
NPR1 natriuretic peptide receptor 1
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OR1E1 olfactory receptor, family 1, subfamily E, member 1
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PASK PAS domain containing serine/threonine kinase
PCDHA5 protocadherin alpha 5
PCNXL2 pecanex-like 2 (Drosophila)
PCSK6 proprotein convertase subtilisin/kexin type 6
PDGFB platelet-derived growth factor beta polypeptide
PGAP3 post-GPI attachment to proteins 3
POFUT1 protein O-fucosyltransferase 1
PRB1 proline-rich protein BstNI subfamily 1
PRUNE2 prune homolog 2 (Drosophila)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RCN1 reticulocalbin 1, EF-hand calcium binding domain
REEP2 receptor accessory protein 2
RFPL1S RFPL1 antisense RNA 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RTEL1 regulator of telomere elongation helicase 1
RUNX1 runt-related transcription factor 1
S100A7 S100 calcium binding protein A7
SCRG1 stimulator of chondrogenesis 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SFTPB surfactant protein B
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
STARD3 StAR-related lipid transfer (START) domain containing 3
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAS2R10 taste receptor, type 2, member 10
TICAM1 toll-like receptor adaptor molecule 1
TMEM176A transmembrane protein 176A
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
ZBTB22 zinc finger and BTB domain containing 22

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABI3BP ABI family, member 3 (NESH) binding protein
ACBD4 acyl-CoA binding domain containing 4
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRE5 adhesion G protein-coupled receptor E5
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
ATP10D ATPase, class V, type 10D
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BST2 bone marrow stromal cell antigen 2
C10ORF95 chromosome 10 open reading frame 95
C1ORF159 chromosome 1 open reading frame 159
CAPN15 calpain 15
CBX4 chromobox homolog 4
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CLCF1 cardiotrophin-like cytokine factor 1
CLSPN claspin
COBL cordon-bleu WH2 repeat protein
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBF4B DBF4 zinc finger B
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAL4 dynein, axonemal, light chain 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK1 dedicator of cytokinesis 1
EXD3 exonuclease 3'-5' domain containing 3
FAM189A2 family with sequence similarity 189, member A2
GLB1L galactosidase, beta 1-like
GLCE glucuronic acid epimerase
GRB7 growth factor receptor-bound protein 7
GUSBP3 glucuronidase, beta pseudogene 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HIST1H2BO histone cluster 1, H2bo
HIST1H3E histone cluster 1, H3e
HIST2H2AA3 histone cluster 2, H2aa3
IFI6 interferon, alpha-inducible protein 6
INPP5J inositol polyphosphate-5-phosphatase J
KPNA5 karyopherin alpha 5 (importin alpha 6)
KREMEN2 kringle containing transmembrane protein 2
LHFPL2 lipoma HMGIC fusion partner-like 2
LOC100286895 cell division cycle 27 homolog pseudogene
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCC mutated in colorectal cancers
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MPI mannose phosphate isomerase
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MRPL41 mitochondrial ribosomal protein L41
MRPS18C mitochondrial ribosomal protein S18C
NAV2 neuron navigator 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NIPAL2 NIPA-like domain containing 2
NME6 NME/NM23 nucleoside diphosphate kinase 6
NXPE3 neurexophilin and PC-esterase domain family, member 3
PCDHB13 protocadherin beta 13
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD2 phospholipase D2
POLH polymerase (DNA directed), eta
PPT2 palmitoyl-protein thioesterase 2
PRKCE protein kinase C, epsilon
RAD54L2 RAD54-like 2 (S. cerevisiae)
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RPGRIP1L RPGRIP1-like
SASH1 SAM and SH3 domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SENP7 SUMO1/sentrin specific peptidase 7
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SETD1A SET domain containing 1A
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPIDR scaffolding protein involved in DNA repair
STEAP1 six transmembrane epithelial antigen of the prostate 1
STEAP4 STEAP family member 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D17 TBC1 domain family, member 17
TESC tescalcin
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THBS3 thrombospondin 3
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM7SF3 transmembrane 7 superfamily member 3
TRIM5 tripartite motif containing 5
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBG2 tubulin, gamma 2
TWISTNB TWIST neighbor
VIPR1 vasoactive intestinal peptide receptor 1
WDR18 WD repeat domain 18
ZFP30 ZFP30 zinc finger protein
ZNF350 zinc finger protein 350
ZNF480 zinc finger protein 480
ZNF747 zinc finger protein 747
ZNF778 zinc finger protein 778