fertilization Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). (Gene Ontology, GO_0009566)
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Genes

102 genes co-occuring with the biological term fertilization in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACR acrosin
ADAM2 ADAM metallopeptidase domain 2
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AFP alpha-fetoprotein
AMH anti-Mullerian hormone
BMP15 bone morphogenetic protein 15
C1QBP complement component 1, q subcomponent binding protein
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CD52 CD52 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CGA glycoprotein hormones, alpha polypeptide
CGB chorionic gonadotropin, beta polypeptide
CPT2 carnitine palmitoyltransferase 2
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CST8 cystatin 8 (cystatin-related epididymal specific)
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DPPA3 developmental pluripotency associated 3
EGFR epidermal growth factor receptor
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
ESR2 estrogen receptor 2 (ER beta)
FGF1 fibroblast growth factor 1 (acidic)
FLT1 fms-related tyrosine kinase 1
FMR1 fragile X mental retardation 1
FN1 fibronectin 1
FSHR follicle stimulating hormone receptor
GALT galactose-1-phosphate uridylyltransferase
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GDF9 growth differentiation factor 9
GHRL ghrelin/obestatin prepropeptide
GPX4 glutathione peroxidase 4
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
H19 H19, imprinted maternally expressed transcript (non-protein coding)
HLA-G major histocompatibility complex, class I, G
IGF1R insulin-like growth factor 1 receptor
IGFBP1 insulin-like growth factor binding protein 1
IL15 interleukin 15
IL18 interleukin 18
IL2RA interleukin 2 receptor, alpha
INHA inhibin, alpha
INHBB inhibin, beta B
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
KITLG KIT ligand
LEP leptin
LHCGR luteinizing hormone/choriogonadotropin receptor
LIF leukemia inhibitory factor
MBL2 mannose-binding lectin (protein C) 2, soluble
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae)
MPDZ multiple PDZ domain protein
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NEU1 sialidase 1 (lysosomal sialidase)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OVGP1 oviductal glycoprotein 1, 120kDa
PAEP progestagen-associated endometrial protein
PARK7 parkinson protein 7
PGF placental growth factor
PGR progesterone receptor
PLCZ1 phospholipase C, zeta 1
PPARG peroxisome proliferator-activated receptor gamma
PRM1 protamine 1
PRM2 protamine 2
PRNP prion protein
PTX3 pentraxin 3, long
SAA1 serum amyloid A1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHBG sex hormone-binding globulin
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SOD2 superoxide dismutase 2, mitochondrial
SPA17 sperm autoantigenic protein 17
SPAG1 sperm associated antigen 1
SPATA22 spermatogenesis associated 22
SPATA9 spermatogenesis associated 9
STAR steroidogenic acute regulatory protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNP1 transition protein 1 (during histone to protamine replacement)
TXNDC8 thioredoxin domain containing 8 (spermatozoa)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VEGFA vascular endothelial growth factor A
WBP2NL WBP2 N-terminal like
ZP1 zona pellucida glycoprotein 1 (sperm receptor)