fetal ultrasound soft marker Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description An finding upon obstetric ultrasound examination performed at around 16 to 20 weeks of gestation that is abnormal but not clearly identifiable as a fetal anatomic malformation or growth restriction. Such findings are known as soft markers since they are associated with increased risk for fetal aneuploidy or other disorders. (Human Phenotype Ontology, HP_0011425)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0011425
Similar Terms
Downloads & Tools

Genes

45 genes associated with the fetal ultrasound soft marker phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
A2ML1 alpha-2-macroglobulin-like 1
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
BRAF B-Raf proto-oncogene, serine/threonine kinase
CCDC22 coiled-coil domain containing 22
COL2A1 collagen, type II, alpha 1
EFNB1 ephrin-B1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FANCB Fanconi anemia, complementation group B
FOXF1 forkhead box F1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA6 GATA binding protein 6
HOXD13 homeobox D13
HRAS Harvey rat sarcoma viral oncogene homolog
INSR insulin receptor
KAT6B K(lysine) acetyltransferase 6B
KIAA0196 KIAA0196
KRAS Kirsten rat sarcoma viral oncogene homolog
MKS1 Meckel syndrome, type 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OFD1 oral-facial-digital syndrome 1
PEX1 peroxisomal biogenesis factor 1
PEX10 peroxisomal biogenesis factor 10
PEX11B peroxisomal biogenesis factor 11 beta
PEX12 peroxisomal biogenesis factor 12
PEX13 peroxisomal biogenesis factor 13
PEX14 peroxisomal biogenesis factor 14
PEX16 peroxisomal biogenesis factor 16
PEX19 peroxisomal biogenesis factor 19
PEX2 peroxisomal biogenesis factor 2
PEX26 peroxisomal biogenesis factor 26
PEX3 peroxisomal biogenesis factor 3
PEX5 peroxisomal biogenesis factor 5
PEX6 peroxisomal biogenesis factor 6
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RIT1 Ras-like without CAAX 1
RNU4ATAC RNA, U4atac small nuclear (U12-dependent splicing)
SCARF2 scavenger receptor class F, member 2
SETBP1 SET binding protein 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SOS1 son of sevenless homolog 1 (Drosophila)
TRIP11 thyroid hormone receptor interactor 11
UBA1 ubiquitin-like modifier activating enzyme 1
VANGL1 VANGL planar cell polarity protein 1
WNT3 wingless-type MMTV integration site family, member 3