fibrinogen Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds. (Gene Ontology, GO_0005577)
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Genes

131 genes co-occuring with the biological term fibrinogen in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ADIPOQ adiponectin, C1Q and collagen domain containing
ALB albumin
APCS amyloid P component, serum
APOA1 apolipoprotein A-I
APOA5 apolipoprotein A-V
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ARC activity-regulated cytoskeleton-associated protein
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
CD44 CD44 molecule (Indian blood group)
CD47 CD47 molecule
CD63 CD63 molecule
CFH complement factor H
CLU clusterin
CP ceruloplasmin (ferroxidase)
CPB2 carboxypeptidase B2 (plasma)
CPN1 carboxypeptidase N, polypeptide 1
CRP C-reactive protein, pentraxin-related
CSK c-src tyrosine kinase
CXCL8 chemokine (C-X-C motif) ligand 8
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
EFNB1 ephrin-B1
EGFR epidermal growth factor receptor
ENO1 enolase 1, (alpha)
EPHA4 EPH receptor A4
EPHB1 EPH receptor B1
ESR2 estrogen receptor 2 (ER beta)
F10 coagulation factor X
F12 coagulation factor XII (Hageman factor)
F13A1 coagulation factor XIII, A1 polypeptide
F13B coagulation factor XIII, B polypeptide
F2 coagulation factor II (thrombin)
F2RL2 coagulation factor II (thrombin) receptor-like 2
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
FBLN1 fibulin 1
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FERMT3 fermitin family member 3
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FGG fibrinogen gamma chain
FN1 fibronectin 1
FOXA1 forkhead box A1
FOXA2 forkhead box A2
FOXA3 forkhead box A3
FSBP fibrinogen silencer binding protein
FYB FYN binding protein
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP1BB glycoprotein Ib (platelet), beta polypeptide
GP5 glycoprotein V (platelet)
GP6 glycoprotein VI (platelet)
GP9 glycoprotein IX (platelet)
HABP2 hyaluronan binding protein 2
HP haptoglobin
ICAM1 intercellular adhesion molecule 1
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL4 interleukin 4
IL6 interleukin 6
INS insulin
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KNG1 kininogen 1
LPA lipoprotein, Lp(a)
LRP1B low density lipoprotein receptor-related protein 1B
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MIR18A microRNA 18a
MMP12 matrix metallopeptidase 12
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MUC1 mucin 1, cell surface associated
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS3 nitric oxide synthase 3 (endothelial cell)
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PADI4 peptidyl arginine deiminase, type IV
PCSK9 proprotein convertase subtilisin/kexin type 9
PDIA3 protein disulfide isomerase family A, member 3
PDIA6 protein disulfide isomerase family A, member 6
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAT plasminogen activator, tissue
PLAUR plasminogen activator, urokinase receptor
PLG plasminogen
PPARG peroxisome proliferator-activated receptor gamma
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PROS1 protein S (alpha)
PSG5 pregnancy specific beta-1-glycoprotein 5
PTK2B protein tyrosine kinase 2 beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RLN2 relaxin 2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRSF1 serine/arginine-rich splicing factor 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGM3 transglutaminase 3
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR4 toll-like receptor 4
TMSB4X thymosin beta 4, X-linked
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TTR transthyretin
VCL vinculin
VWF von Willebrand factor
ZPR1 ZPR1 zinc finger