fibroids Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues.|A benign smooth muscle neoplasm arising from the body of the uterus. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern.|An uncommon benign neoplasm arising from the bone. It is characterized by the presence of spindle-shaped or stellate chondrocytes, a lobulated growth pattern, myxoid stroma formation, and sometimes multinucleated giant cells. It has been associated with chromosomal rearrangement of 6q13 and 6q25 bands. The most common clinical symptom is mild, localized pain. (Experimental Factor Ontology, EFO_0000731)
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Genes

30 genes co-occuring with the biological term fibroids in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
COMT catechol-O-methyltransferase
CXCL10 chemokine (C-X-C motif) ligand 10
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FH fumarate hydratase
HMGA2 high mobility group AT-hook 2
IL10 interleukin 10
IL13 interleukin 13
IL17A interleukin 17A
MUC16 mucin 16, cell surface associated
NPY neuropeptide Y
NTS neurotensin
OXT oxytocin/neurophysin I prepropeptide
PAEP progestagen-associated endometrial protein
PDGFC platelet derived growth factor C
PENK proenkephalin
PEPD peptidase D
PGR progesterone receptor
PRLHR prolactin releasing hormone receptor
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
REST RE1-silencing transcription factor
TAC1 tachykinin, precursor 1
THBD thrombomodulin
THBS1 thrombospondin 1
THBS2 thrombospondin 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VIP vasoactive intestinal peptide