finasteride-2206 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the finasteride-2206 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD2 abhydrolase domain containing 2
ABHD6 abhydrolase domain containing 6
ABLIM1 actin binding LIM protein 1
ACAN aggrecan
ACTC1 actin, alpha, cardiac muscle 1
ACVR2A activin A receptor, type IIA
AGFG1 ArfGAP with FG repeats 1
ALOXE3 arachidonate lipoxygenase 3
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APOL2 apolipoprotein L, 2
ATG10 autophagy related 10
ATG3 autophagy related 3
ATP9B ATPase, class II, type 9B
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BRS3 bombesin-like receptor 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C17ORF59 chromosome 17 open reading frame 59
C21ORF2 chromosome 21 open reading frame 2
C3ORF18 chromosome 3 open reading frame 18
CHN2 chimerin 2
CHPF chondroitin polymerizing factor
CLCA2 chloride channel accessory 2
CLTA clathrin, light chain A
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DDAH2 dimethylarginine dimethylaminohydrolase 2
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DSC3 desmocollin 3
DSCAM Down syndrome cell adhesion molecule
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EDNRA endothelin receptor type A
ELL elongation factor RNA polymerase II
ERC2-IT1 ERC2 intronic transcript 1
F5 coagulation factor V (proaccelerin, labile factor)
FAM163A family with sequence similarity 163, member A
FGF23 fibroblast growth factor 23
FOXD1 forkhead box D1
FOXO1 forkhead box O1
FSCN3 fascin actin-bundling protein 3, testicular
FZD4 frizzled class receptor 4
GFER growth factor, augmenter of liver regeneration
GPR162 G protein-coupled receptor 162
GPX2 glutathione peroxidase 2
GSTTP1 glutathione S-transferase theta pseudogene 1
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IL6ST interleukin 6 signal transducer
IQCG IQ motif containing G
ITGA10 integrin, alpha 10
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIF25 kinesin family member 25
LDLR low density lipoprotein receptor
LGALS4 lectin, galactoside-binding, soluble, 4
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LMOD1 leiomodin 1 (smooth muscle)
MBD3 methyl-CpG binding domain protein 3
MBNL1 muscleblind-like splicing regulator 1
MFAP3L microfibrillar-associated protein 3-like
MSRB2 methionine sulfoxide reductase B2
MVP major vault protein
NOX1 NADPH oxidase 1
NPPA natriuretic peptide A
NRP1 neuropilin 1
OLFML2B olfactomedin-like 2B
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PDE8B phosphodiesterase 8B
PDGFB platelet-derived growth factor beta polypeptide
PHLDB1 pleckstrin homology-like domain, family B, member 1
PICALM phosphatidylinositol binding clathrin assembly protein
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLD3 phospholipase D family, member 3
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PMP22 peripheral myelin protein 22
POFUT1 protein O-fucosyltransferase 1
POLL polymerase (DNA directed), lambda
POU2F2 POU class 2 homeobox 2
PPAP2B phosphatidic acid phosphatase type 2B
PTEN phosphatase and tensin homolog
RB1 retinoblastoma 1
RGS12 regulator of G-protein signaling 12
RIBC2 RIB43A domain with coiled-coils 2
SIN3B SIN3 transcription regulator family member B
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLN sarcolipin
SORBS3 sorbin and SH3 domain containing 3
SPTB spectrin, beta, erythrocytic
SYNC syncoilin, intermediate filament protein
TNIK TRAF2 and NCK interacting kinase
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
UMPS uridine monophosphate synthetase
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
UPK1A uroplakin 1A
VASH1 vasohibin 1
VCL vinculin
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF280B zinc finger protein 280B
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACO1 aconitase 1, soluble
ADGRE3 adhesion G protein-coupled receptor E3
BIK BCL2-interacting killer (apoptosis-inducing)
BMP8B bone morphogenetic protein 8b
BTBD7 BTB (POZ) domain containing 7
C5 complement component 5
C5AR1 complement component 5a receptor 1
CA11 carbonic anhydrase XI
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CBX4 chromobox homolog 4
CEP41 centrosomal protein 41kDa
CES3 carboxylesterase 3
CLCN2 chloride channel, voltage-sensitive 2
CLCN6 chloride channel, voltage-sensitive 6
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
EDAR ectodysplasin A receptor
EFNA3 ephrin-A3
ERAP2 endoplasmic reticulum aminopeptidase 2
FAM102A family with sequence similarity 102, member A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
GID4 GID complex subunit 4
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GP1BA glycoprotein Ib (platelet), alpha polypeptide
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H2AM histone cluster 1, H2am
HIST1H3H histone cluster 1, H3h
HIST1H4F histone cluster 1, H4f
HOXC8 homeobox C8
HYAL2 hyaluronoglucosaminidase 2
IFI6 interferon, alpha-inducible protein 6
IFT140 intraflagellar transport 140
IQCC IQ motif containing C
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLK6 kallikrein-related peptidase 6
KRT8P12 keratin 8 pseudogene 12
LOC100286895 cell division cycle 27 homolog pseudogene
LOC390998 ribosomal protein L10 pseudogene
MED9 mediator complex subunit 9
MUC3A mucin 3A, cell surface associated
MYBPH myosin binding protein H
NARFL nuclear prelamin A recognition factor-like
NBEA neurobeachin
NIPAL2 NIPA-like domain containing 2
NME8 NME/NM23 family member 8
NPFFR1 neuropeptide FF receptor 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NRGN neurogranin (protein kinase C substrate, RC3)
NXPE3 neurexophilin and PC-esterase domain family, member 3
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PADI1 peptidyl arginine deiminase, type I
PADI2 peptidyl arginine deiminase, type II
PCDHGA10 protocadherin gamma subfamily A, 10
PGPEP1 pyroglutamyl-peptidase I
PLCB4 phospholipase C, beta 4
PNRC1 proline-rich nuclear receptor coactivator 1
PRKCE protein kinase C, epsilon
PTPRS protein tyrosine phosphatase, receptor type, S
RFPL3 ret finger protein-like 3
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RPL13P5 ribosomal protein L13 pseudogene 5
SALL2 spalt-like transcription factor 2
SCAMP5 secretory carrier membrane protein 5
SEC14L5 SEC14-like 5 (S. cerevisiae)
SERGEF secretion regulating guanine nucleotide exchange factor
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SGCE sarcoglycan, epsilon
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STARD5 StAR-related lipid transfer (START) domain containing 5
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMC7 transmembrane channel-like 7
TMEM104 transmembrane protein 104
TMEM209 transmembrane protein 209
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNNT1 troponin T type 1 (skeletal, slow)
TP53I3 tumor protein p53 inducible protein 3
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN13 tetraspanin 13
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
URM1 ubiquitin related modifier 1
USP6NL USP6 N-terminal like
VASH2 vasohibin 2
VN1R1 vomeronasal 1 receptor 1
VSIG10 V-set and immunoglobulin domain containing 10
WNT10B wingless-type MMTV integration site family, member 10B
ZC3H12A zinc finger CCCH-type containing 12A
ZC4H2 zinc finger, C4H2 domain containing
ZNF32 zinc finger protein 32
ZNF668 zinc finger protein 668
ZNF696 zinc finger protein 696