| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the finasteride-2206 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ABHD2 | abhydrolase domain containing 2 |
| ABHD6 | abhydrolase domain containing 6 |
| ABLIM1 | actin binding LIM protein 1 |
| ACAN | aggrecan |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ACVR2A | activin A receptor, type IIA |
| AGFG1 | ArfGAP with FG repeats 1 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| AP3S2 | adaptor-related protein complex 3, sigma 2 subunit |
| APOL2 | apolipoprotein L, 2 |
| ATG10 | autophagy related 10 |
| ATG3 | autophagy related 3 |
| ATP9B | ATPase, class II, type 9B |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B |
| BRS3 | bombesin-like receptor 3 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CHN2 | chimerin 2 |
| CHPF | chondroitin polymerizing factor |
| CLCA2 | chloride channel accessory 2 |
| CLTA | clathrin, light chain A |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DSC3 | desmocollin 3 |
| DSCAM | Down syndrome cell adhesion molecule |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| EDNRA | endothelin receptor type A |
| ELL | elongation factor RNA polymerase II |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FAM163A | family with sequence similarity 163, member A |
| FGF23 | fibroblast growth factor 23 |
| FOXD1 | forkhead box D1 |
| FOXO1 | forkhead box O1 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| FZD4 | frizzled class receptor 4 |
| GFER | growth factor, augmenter of liver regeneration |
| GPR162 | G protein-coupled receptor 162 |
| GPX2 | glutathione peroxidase 2 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IL6ST | interleukin 6 signal transducer |
| IQCG | IQ motif containing G |
| ITGA10 | integrin, alpha 10 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KIF25 | kinesin family member 25 |
| LDLR | low density lipoprotein receptor |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| MBD3 | methyl-CpG binding domain protein 3 |
| MBNL1 | muscleblind-like splicing regulator 1 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MSRB2 | methionine sulfoxide reductase B2 |
| MVP | major vault protein |
| NOX1 | NADPH oxidase 1 |
| NPPA | natriuretic peptide A |
| NRP1 | neuropilin 1 |
| OLFML2B | olfactomedin-like 2B |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PDE8B | phosphodiesterase 8B |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLD3 | phospholipase D family, member 3 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| PMP22 | peripheral myelin protein 22 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POLL | polymerase (DNA directed), lambda |
| POU2F2 | POU class 2 homeobox 2 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PTEN | phosphatase and tensin homolog |
| RB1 | retinoblastoma 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| SIN3B | SIN3 transcription regulator family member B |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLN | sarcolipin |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPTB | spectrin, beta, erythrocytic |
| SYNC | syncoilin, intermediate filament protein |
| TNIK | TRAF2 and NCK interacting kinase |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| UMPS | uridine monophosphate synthetase |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| UPK1A | uroplakin 1A |
| VASH1 | vasohibin 1 |
| VCL | vinculin |
| XPNPEP2 | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF280B | zinc finger protein 280B |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACO1 | aconitase 1, soluble |
| ADGRE3 | adhesion G protein-coupled receptor E3 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BMP8B | bone morphogenetic protein 8b |
| BTBD7 | BTB (POZ) domain containing 7 |
| C5 | complement component 5 |
| C5AR1 | complement component 5a receptor 1 |
| CA11 | carbonic anhydrase XI |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CBX4 | chromobox homolog 4 |
| CEP41 | centrosomal protein 41kDa |
| CES3 | carboxylesterase 3 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| EDAR | ectodysplasin A receptor |
| EFNA3 | ephrin-A3 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| FAM102A | family with sequence similarity 102, member A |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| GID4 | GID complex subunit 4 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H3H | histone cluster 1, H3h |
| HIST1H4F | histone cluster 1, H4f |
| HOXC8 | homeobox C8 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT140 | intraflagellar transport 140 |
| IQCC | IQ motif containing C |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLK6 | kallikrein-related peptidase 6 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOC390998 | ribosomal protein L10 pseudogene |
| MED9 | mediator complex subunit 9 |
| MUC3A | mucin 3A, cell surface associated |
| MYBPH | myosin binding protein H |
| NARFL | nuclear prelamin A recognition factor-like |
| NBEA | neurobeachin |
| NIPAL2 | NIPA-like domain containing 2 |
| NME8 | NME/NM23 family member 8 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PADI1 | peptidyl arginine deiminase, type I |
| PADI2 | peptidyl arginine deiminase, type II |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLCB4 | phospholipase C, beta 4 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PRKCE | protein kinase C, epsilon |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RFPL3 | ret finger protein-like 3 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SALL2 | spalt-like transcription factor 2 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SETD1A | SET domain containing 1A |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGCE | sarcoglycan, epsilon |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMC7 | transmembrane channel-like 7 |
| TMEM104 | transmembrane protein 104 |
| TMEM209 | transmembrane protein 209 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TP53I3 | tumor protein p53 inducible protein 3 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSPAN13 | tetraspanin 13 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| URM1 | ubiquitin related modifier 1 |
| USP6NL | USP6 N-terminal like |
| VASH2 | vasohibin 2 |
| VN1R1 | vomeronasal 1 receptor 1 |
| VSIG10 | V-set and immunoglobulin domain containing 10 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZNF32 | zinc finger protein 32 |
| ZNF668 | zinc finger protein 668 |
| ZNF696 | zinc finger protein 696 |