finasteride-3744 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the finasteride-3744 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
AKAP4 A kinase (PRKA) anchor protein 4
AMN amnion associated transmembrane protein
ANGEL2 angel homolog 2 (Drosophila)
ANK2 ankyrin 2, neuronal
ARR3 arrestin 3, retinal (X-arrestin)
ART1 ADP-ribosyltransferase 1
ARTN artemin
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BBC3 BCL2 binding component 3
BMP1 bone morphogenetic protein 1
C2ORF72 chromosome 2 open reading frame 72
C6 complement component 6
CALCR calcitonin receptor
CASP4 caspase 4, apoptosis-related cysteine peptidase
CD40 CD40 molecule, TNF receptor superfamily member 5
CD58 CD58 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEMIP cell migration inducing protein, hyaluronan binding
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COPZ2 coatomer protein complex, subunit zeta 2
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CTIF CBP80/20-dependent translation initiation factor
DGCR2 DiGeorge syndrome critical region gene 2
DOCK6 dedicator of cytokinesis 6
DPF1 D4, zinc and double PHD fingers family 1
DTX3 deltex 3, E3 ubiquitin ligase
EGR1 early growth response 1
ESR1 estrogen receptor 1
ESRRG estrogen-related receptor gamma
FGF22 fibroblast growth factor 22
FLRT2 fibronectin leucine rich transmembrane protein 2
FLT4 fms-related tyrosine kinase 4
FRMD4B FERM domain containing 4B
FUBP1 far upstream element (FUSE) binding protein 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GLRA3 glycine receptor, alpha 3
GPER1 G protein-coupled estrogen receptor 1
GPR19 G protein-coupled receptor 19
GPR27 G protein-coupled receptor 27
GRM2 glutamate receptor, metabotropic 2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HRG histidine-rich glycoprotein
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IGHM immunoglobulin heavy constant mu
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KIAA0040 KIAA0040
KIAA0319L KIAA0319-like
LAMA2 laminin, alpha 2
LHB luteinizing hormone beta polypeptide
LINC00115 long intergenic non-protein coding RNA 115
LRP1 low density lipoprotein receptor-related protein 1
LY6G6E lymphocyte antigen 6 complex, locus G6E (pseudogene)
MCF2L MCF.2 cell line derived transforming sequence-like
MED25 mediator complex subunit 25
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYT1 myelin transcription factor 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCR2 natural cytotoxicity triggering receptor 2
NRP2 neuropilin 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
ORM1 orosomucoid 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDLIM4 PDZ and LIM domain 4
PGP phosphoglycolate phosphatase
PHOX2A paired-like homeobox 2a
PLCH2 phospholipase C, eta 2
POM121L2 POM121 transmembrane nucleoporin-like 2
POSTN periostin, osteoblast specific factor
PQLC2 PQ loop repeat containing 2
PRDX2 peroxiredoxin 2
PRKCE protein kinase C, epsilon
PROSC proline synthetase co-transcribed homolog (bacterial)
PRPH2 peripherin 2 (retinal degeneration, slow)
RAD51 RAD51 recombinase
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RHEB Ras homolog enriched in brain
SCAND2P SCAN domain containing 2 pseudogene
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SH3BP2 SH3-domain binding protein 2
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC17A2 solute carrier family 17, member 2
TAS2R1 taste receptor, type 2, member 1
TJAP1 tight junction associated protein 1 (peripheral)
TJP3 tight junction protein 3
USP22 ubiquitin specific peptidase 22
WNT3 wingless-type MMTV integration site family, member 3
ZNF280A zinc finger protein 280A
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
AHSG alpha-2-HS-glycoprotein
ALPP alkaline phosphatase, placental
ANKFY1 ankyrin repeat and FYVE domain containing 1
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
APOLD1 apolipoprotein L domain containing 1
ARHGAP24 Rho GTPase activating protein 24
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1ORF105 chromosome 1 open reading frame 105
C8ORF60 chromosome 8 open reading frame 60
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDC73 cell division cycle 73
CDH19 cadherin 19, type 2
CDON cell adhesion associated, oncogene regulated
CEP41 centrosomal protein 41kDa
CHM choroideremia (Rab escort protein 1)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNTN1 contactin 1
CNTNAP3B contactin associated protein-like 3B
CREB5 cAMP responsive element binding protein 5
CTC1 CTS telomere maintenance complex component 1
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL6 chemokine (C-X-C motif) ligand 6
DOK5 docking protein 5
DUSP9 dual specificity phosphatase 9
EN2 engrailed homeobox 2
EPN3 epsin 3
FAM189A2 family with sequence similarity 189, member A2
FGL1 fibrinogen-like 1
FOXC1 forkhead box C1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H2AJ histone cluster 1, H2aj
HOXB2 homeobox B2
IFNA14 interferon, alpha 14
IFNA17 interferon, alpha 17
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
LIME1 Lck interacting transmembrane adaptor 1
LINC00341 long intergenic non-protein coding RNA 341
LINC00597 long intergenic non-protein coding RNA 597
LMO7 LIM domain 7
LOC100286895 cell division cycle 27 homolog pseudogene
LOC100287590 uncharacterized LOC100287590
MAGEA5 melanoma antigen family A5
MBNL3 muscleblind-like splicing regulator 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCMBP minichromosome maintenance complex binding protein
MDM4 MDM4, p53 regulator
MED9 mediator complex subunit 9
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MPI mannose phosphate isomerase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTCP1 mature T-cell proliferation 1
MYOZ3 myozenin 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPFFR1 neuropeptide FF receptor 1
NRTN neurturin
OSMR oncostatin M receptor
PC pyruvate carboxylase
PCDHA9 protocadherin alpha 9
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLXNA3 plexin A3
PMCH pro-melanin-concentrating hormone
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRF1 perforin 1 (pore forming protein)
PRSS22 protease, serine, 22
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPS17P5 ribosomal protein S17 pseudogene 5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
S100A3 S100 calcium binding protein A3
SAYSD1 SAYSVFN motif domain containing 1
SCIN scinderin
SETD1A SET domain containing 1A
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLMO1 slowmo homolog 1 (Drosophila)
SMO smoothened, frizzled class receptor
SPRYD7 SPRY domain containing 7
STK16 serine/threonine kinase 16
SUSD4 sushi domain containing 4
TESPA1 thymocyte expressed, positive selection associated 1
TRABD TraB domain containing
TRAC T cell receptor alpha constant
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSNAXIP1 translin-associated factor X interacting protein 1
TUBB2B tubulin, beta 2B class IIb
TWISTNB TWIST neighbor
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VGLL3 vestigial-like family member 3
ZNF268 zinc finger protein 268
ZNF408 zinc finger protein 408
ZNF516 zinc finger protein 516
ZNF702P zinc finger protein 702, pseudogene
ZNF749 zinc finger protein 749