| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the finasteride-3744 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| AKAP4 | A kinase (PRKA) anchor protein 4 |
| AMN | amnion associated transmembrane protein |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ANK2 | ankyrin 2, neuronal |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ART1 | ADP-ribosyltransferase 1 |
| ARTN | artemin |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B |
| BBC3 | BCL2 binding component 3 |
| BMP1 | bone morphogenetic protein 1 |
| C2ORF72 | chromosome 2 open reading frame 72 |
| C6 | complement component 6 |
| CALCR | calcitonin receptor |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CD58 | CD58 molecule |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CROCCP3 | ciliary rootlet coiled-coil, rootletin pseudogene 3 |
| CTIF | CBP80/20-dependent translation initiation factor |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DOCK6 | dedicator of cytokinesis 6 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DTX3 | deltex 3, E3 ubiquitin ligase |
| EGR1 | early growth response 1 |
| ESR1 | estrogen receptor 1 |
| ESRRG | estrogen-related receptor gamma |
| FGF22 | fibroblast growth factor 22 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FLT4 | fms-related tyrosine kinase 4 |
| FRMD4B | FERM domain containing 4B |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GCNT4 | glucosaminyl (N-acetyl) transferase 4, core 2 |
| GLRA3 | glycine receptor, alpha 3 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR19 | G protein-coupled receptor 19 |
| GPR27 | G protein-coupled receptor 27 |
| GRM2 | glutamate receptor, metabotropic 2 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HRG | histidine-rich glycoprotein |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
| IGHM | immunoglobulin heavy constant mu |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ4 | potassium channel, inwardly rectifying subfamily J, member 4 |
| KIAA0040 | KIAA0040 |
| KIAA0319L | KIAA0319-like |
| LAMA2 | laminin, alpha 2 |
| LHB | luteinizing hormone beta polypeptide |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LY6G6E | lymphocyte antigen 6 complex, locus G6E (pseudogene) |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MED25 | mediator complex subunit 25 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| MYT1 | myelin transcription factor 1 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NRP2 | neuropilin 2 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| ORM1 | orosomucoid 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDLIM4 | PDZ and LIM domain 4 |
| PGP | phosphoglycolate phosphatase |
| PHOX2A | paired-like homeobox 2a |
| PLCH2 | phospholipase C, eta 2 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| POSTN | periostin, osteoblast specific factor |
| PQLC2 | PQ loop repeat containing 2 |
| PRDX2 | peroxiredoxin 2 |
| PRKCE | protein kinase C, epsilon |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| RAD51 | RAD51 recombinase |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RHEB | Ras homolog enriched in brain |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
| SLC17A2 | solute carrier family 17, member 2 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TJP3 | tight junction protein 3 |
| USP22 | ubiquitin specific peptidase 22 |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| ZNF280A | zinc finger protein 280A |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| AHSG | alpha-2-HS-glycoprotein |
| ALPP | alkaline phosphatase, placental |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CDC73 | cell division cycle 73 |
| CDH19 | cadherin 19, type 2 |
| CDON | cell adhesion associated, oncogene regulated |
| CEP41 | centrosomal protein 41kDa |
| CHM | choroideremia (Rab escort protein 1) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNTN1 | contactin 1 |
| CNTNAP3B | contactin associated protein-like 3B |
| CREB5 | cAMP responsive element binding protein 5 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| DOK5 | docking protein 5 |
| DUSP9 | dual specificity phosphatase 9 |
| EN2 | engrailed homeobox 2 |
| EPN3 | epsin 3 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FGL1 | fibrinogen-like 1 |
| FOXC1 | forkhead box C1 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXB2 | homeobox B2 |
| IFNA14 | interferon, alpha 14 |
| IFNA17 | interferon, alpha 17 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMO7 | LIM domain 7 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOC100287590 | uncharacterized LOC100287590 |
| MAGEA5 | melanoma antigen family A5 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCMBP | minichromosome maintenance complex binding protein |
| MDM4 | MDM4, p53 regulator |
| MED9 | mediator complex subunit 9 |
| MFI2 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| MPI | mannose phosphate isomerase |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTCP1 | mature T-cell proliferation 1 |
| MYOZ3 | myozenin 3 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRTN | neurturin |
| OSMR | oncostatin M receptor |
| PC | pyruvate carboxylase |
| PCDHA9 | protocadherin alpha 9 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLXNA3 | plexin A3 |
| PMCH | pro-melanin-concentrating hormone |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRF1 | perforin 1 (pore forming protein) |
| PRSS22 | protease, serine, 22 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| S100A3 | S100 calcium binding protein A3 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCIN | scinderin |
| SETD1A | SET domain containing 1A |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMO | smoothened, frizzled class receptor |
| SPRYD7 | SPRY domain containing 7 |
| STK16 | serine/threonine kinase 16 |
| SUSD4 | sushi domain containing 4 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TRABD | TraB domain containing |
| TRAC | T cell receptor alpha constant |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TUBB2B | tubulin, beta 2B class IIb |
| TWISTNB | TWIST neighbor |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VGLL3 | vestigial-like family member 3 |
| ZNF268 | zinc finger protein 268 |
| ZNF408 | zinc finger protein 408 |
| ZNF516 | zinc finger protein 516 |
| ZNF702P | zinc finger protein 702, pseudogene |
| ZNF749 | zinc finger protein 749 |