finasteride-4300 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the finasteride-4300 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANKLE2 ankyrin repeat and LEM domain containing 2
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASIC4 acid sensing (proton gated) ion channel family member 4
C5AR1 complement component 5a receptor 1
C5ORF45 chromosome 5 open reading frame 45
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASQ2 calsequestrin 2 (cardiac muscle)
CD6 CD6 molecule
CDHR2 cadherin-related family member 2
CDKL5 cyclin-dependent kinase-like 5
CFAP74 cilia and flagella associated protein 74
COL16A1 collagen, type XVI, alpha 1
CRYGD crystallin, gamma D
CT62 cancer/testis antigen 62
CTNS cystinosin, lysosomal cystine transporter
CTSS cathepsin S
CXCL9 chemokine (C-X-C motif) ligand 9
DKFZP434C153 DKFZP434C153 protein
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYM dymeclin
DZIP1 DAZ interacting zinc finger protein 1
EMILIN2 elastin microfibril interfacer 2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERN2 endoplasmic reticulum to nucleus signaling 2
FABP3 fatty acid binding protein 3, muscle and heart
FBXO41 F-box protein 41
GGT1 gamma-glutamyltransferase 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HAO1 hydroxyacid oxidase (glycolate oxidase) 1
HIST1H4C histone cluster 1, H4c
HNF1B HNF1 homeobox B
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL5RA interleukin 5 receptor, alpha
INA internexin neuronal intermediate filament protein, alpha
INO80D INO80 complex subunit D
IRF4 interferon regulatory factor 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KRTAP2-4 keratin associated protein 2-4
LAT2 linker for activation of T cells family, member 2
LOC440895 two pore channel 3 pseudogene
MCHR1 melanin-concentrating hormone receptor 1
MED18 mediator complex subunit 18
MOGAT2 monoacylglycerol O-acyltransferase 2
MORN1 MORN repeat containing 1
MSH4 mutS homolog 4
N4BP1 NEDD4 binding protein 1
N4BP2L1 NEDD4 binding protein 2-like 1
NEK9 NIMA-related kinase 9
ONECUT2 one cut homeobox 2
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PDE8B phosphodiesterase 8B
PER2 period circadian clock 2
PKNOX1 PBX/knotted 1 homeobox 1
PKP3 plakophilin 3
PKP4 plakophilin 4
PLAC4 placenta-specific 4
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAB27B RAB27B, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RECQL5 RecQ protein-like 5
RGS12 regulator of G-protein signaling 12
RIMS2 regulating synaptic membrane exocytosis 2
RIMS3 regulating synaptic membrane exocytosis 3
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFTPB surfactant protein B
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC16A6 solute carrier family 16, member 6
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SRF serum response factor (c-fos serum response element-binding transcription factor)
STMN1 stathmin 1
SUGP1 SURP and G patch domain containing 1
SYT2 synaptotagmin II
T T, brachyury homolog (mouse)
TACC1 transforming, acidic coiled-coil containing protein 1
TACR1 tachykinin receptor 1
TBX1 T-box 1
TCL1A T-cell leukemia/lymphoma 1A
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TLDC1 TBC/LysM-associated domain containing 1
TP53I11 tumor protein p53 inducible protein 11
ZIM2 zinc finger, imprinted 2
ZNF235 zinc finger protein 235
ZNF280B zinc finger protein 280B
ZNF343 zinc finger protein 343
ZNF518A zinc finger protein 518A
ZNF589 zinc finger protein 589
ZNF614 zinc finger protein 614

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ADGRB2 adhesion G protein-coupled receptor B2
ALOX12 arachidonate 12-lipoxygenase
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APOL6 apolipoprotein L, 6
ARHGAP22 Rho GTPase activating protein 22
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARMC4 armadillo repeat containing 4
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BATF3 basic leucine zipper transcription factor, ATF-like 3
C11ORF21 chromosome 11 open reading frame 21
C17ORF80 chromosome 17 open reading frame 80
CAPN15 calpain 15
CARM1 coactivator-associated arginine methyltransferase 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX8 chromobox homolog 8
CCDC106 coiled-coil domain containing 106
CCDC7 coiled-coil domain containing 7
CCNO cyclin O
CD79B CD79b molecule, immunoglobulin-associated beta
CD82 CD82 molecule
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK3 cyclin-dependent kinase 3
CFAP45 cilia and flagella associated protein 45
CFAP69 cilia and flagella associated protein 69
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CRMP1 collapsin response mediator protein 1
CRY2 cryptochrome circadian clock 2
CXCL3 chemokine (C-X-C motif) ligand 3
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFNB1 ephrin-B1
ELP6 elongator acetyltransferase complex subunit 6
ETV7 ets variant 7
EVPL envoplakin
FBRS fibrosin
FBXO31 F-box protein 31
FGF23 fibroblast growth factor 23
GALK1 galactokinase 1
GBP2 guanylate binding protein 2, interferon-inducible
GRM6 glutamate receptor, metabotropic 6
H1F0 H1 histone family, member 0
HHLA3 HERV-H LTR-associating 3
HIST1H2BJ histone cluster 1, H2bj
HOXA7 homeobox A7
HOXC13 homeobox C13
HYAL3 hyaluronoglucosaminidase 3
ISYNA1 inositol-3-phosphate synthase 1
ITK IL2-inducible T-cell kinase
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRRC15 leucine rich repeat containing 15
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGEB2 melanoma antigen family B2
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP3 matrix metallopeptidase 3
MXRA8 matrix-remodelling associated 8
MYOZ3 myozenin 3
NGF nerve growth factor (beta polypeptide)
NOL6 nucleolar protein 6 (RNA-associated)
NOTCH4 notch 4
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OR3A3 olfactory receptor, family 3, subfamily A, member 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCDHA9 protocadherin alpha 9
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLD3 phospholipase D family, member 3
POLL polymerase (DNA directed), lambda
PROX1 prospero homeobox 1
PTPRU protein tyrosine phosphatase, receptor type, U
RPAP1 RNA polymerase II associated protein 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPTBN2 spectrin, beta, non-erythrocytic 2
SSBP3 single stranded DNA binding protein 3
STAG3 stromal antigen 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TLN1 talin 1
TMEM53 transmembrane protein 53
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSNAXIP1 translin-associated factor X interacting protein 1
TUBA4B tubulin, alpha 4b
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
WNT10B wingless-type MMTV integration site family, member 10B
ZFHX2 zinc finger homeobox 2
ZIC3 Zic family member 3
ZNF573 zinc finger protein 573
ZNF747 zinc finger protein 747
ZYX zyxin