finasteride-6062 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the finasteride-6062 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGFG1 ArfGAP with FG repeats 1
AMPD1 adenosine monophosphate deaminase 1
AMT aminomethyltransferase
ANPEP alanyl (membrane) aminopeptidase
ARHGAP26 Rho GTPase activating protein 26
ATP11A ATPase, class VI, type 11A
ATP9A ATPase, class II, type 9A
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BGN biglycan
C14ORF79 chromosome 14 open reading frame 79
C17ORF53 chromosome 17 open reading frame 53
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CCDC64 coiled-coil domain containing 64
CD200 CD200 molecule
CD48 CD48 molecule
CDHR2 cadherin-related family member 2
CEP112 centrosomal protein 112kDa
CLEC11A C-type lectin domain family 11, member A
COL6A1 collagen, type VI, alpha 1
CREBBP CREB binding protein
CRTC1 CREB regulated transcription coactivator 1
CXCR4 chemokine (C-X-C motif) receptor 4
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DCN decorin
DGCR8 DGCR8 microprocessor complex subunit
DNAH7 dynein, axonemal, heavy chain 7
DOK4 docking protein 4
ECE1 endothelin converting enzyme 1
FAM212B family with sequence similarity 212, member B
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGD1 FYVE, RhoGEF and PH domain containing 1
FGFR1 fibroblast growth factor receptor 1
FXYD5 FXYD domain containing ion transport regulator 5
GAS7 growth arrest-specific 7
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GK3P glycerol kinase 3 pseudogene
GLYAT glycine-N-acyltransferase
GPR137 G protein-coupled receptor 137
GTDC1 glycosyltransferase-like domain containing 1
GUSBP3 glucuronidase, beta pseudogene 3
HCK HCK proto-oncogene, Src family tyrosine kinase
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HEG1 heart development protein with EGF-like domains 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
IFI6 interferon, alpha-inducible protein 6
IL10 interleukin 10
IL1R2 interleukin 1 receptor, type II
IL33R interleukin 33 receptor
KIF1C kinesin family member 1C
KLHL24 kelch-like family member 24
KRT83 keratin 83, type II
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
LYZL6 lysozyme-like 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MEG3 maternally expressed 3 (non-protein coding)
METTL5 methyltransferase like 5
MINK1 misshapen-like kinase 1
MST1 macrophage stimulating 1
MX1 MX dynamin-like GTPase 1
MXD3 MAX dimerization protein 3
MYH14 myosin, heavy chain 14, non-muscle
NME5 NME/NM23 family member 5
NOVA2 neuro-oncological ventral antigen 2
NPY2R neuropeptide Y receptor Y2
PDIA2 protein disulfide isomerase family A, member 2
PHF20L1 PHD finger protein 20-like 1
PLCD1 phospholipase C, delta 1
POLM polymerase (DNA directed), mu
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAB3B RAB3B, member RAS oncogene family
RGS12 regulator of G-protein signaling 12
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPL23AP32 ribosomal protein L23a pseudogene 32
SLC17A4 solute carrier family 17, member 4
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SNPH syntaphilin
SPEF1 sperm flagellar 1
SPG20 spastic paraplegia 20 (Troyer syndrome)
ST5 suppression of tumorigenicity 5
STK4 serine/threonine kinase 4
STMN4 stathmin-like 4
STON1 stonin 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAPBP TAP binding protein (tapasin)
TBX3 T-box 3
TGM2 transglutaminase 2
TJAP1 tight junction associated protein 1 (peripheral)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
UNC5B unc-5 homolog B (C. elegans)
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
WNT16 wingless-type MMTV integration site family, member 16
ZDHHC8P1 zinc finger, DHHC-type containing 8 pseudogene 1
ZNF493 zinc finger protein 493

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
AEN apoptosis enhancing nuclease
ALOX15 arachidonate 15-lipoxygenase
ANKRD7 ankyrin repeat domain 7
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARPIN actin-related protein 2/3 complex inhibitor
B9D2 B9 protein domain 2
BAG4 BCL2-associated athanogene 4
BCL2A1 BCL2-related protein A1
C10ORF95 chromosome 10 open reading frame 95
C1QTNF3 C1q and tumor necrosis factor related protein 3
C7ORF43 chromosome 7 open reading frame 43
CAPG capping protein (actin filament), gelsolin-like
CCDC121 coiled-coil domain containing 121
CCDC186 coiled-coil domain containing 186
CCDC69 coiled-coil domain containing 69
CD34 CD34 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CHRM3 cholinergic receptor, muscarinic 3
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLDN17 claudin 17
CNTFR ciliary neurotrophic factor receptor
CPN2 carboxypeptidase N, polypeptide 2
CXCR2 chemokine (C-X-C motif) receptor 2
DES desmin
DGKE diacylglycerol kinase, epsilon 64kDa
DPYS dihydropyrimidinase
DRD1 dopamine receptor D1
DYSF dysferlin
ELSPBP1 epididymal sperm binding protein 1
EN2 engrailed homeobox 2
FMOD fibromodulin
FOSL1 FOS-like antigen 1
GAMT guanidinoacetate N-methyltransferase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPATCH3 G patch domain containing 3
GPR15 G protein-coupled receptor 15
GPR21 G protein-coupled receptor 21
GPR75 G protein-coupled receptor 75
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXA2 homeobox A2
HRH2 histamine receptor H2
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
ICOS inducible T-cell co-stimulator
IFNA14 interferon, alpha 14
IGKV3-20 immunoglobulin kappa variable 3-20
IL22 interleukin 22
INSL4 insulin-like 4 (placenta)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KPNA5 karyopherin alpha 5 (importin alpha 6)
KREMEN2 kringle containing transmembrane protein 2
KRT24 keratin 24, type I
LMX1B LIM homeobox transcription factor 1, beta
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP2 microtubule-associated protein 2
MATK megakaryocyte-associated tyrosine kinase
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MMP2 matrix metallopeptidase 2
NNAT neuronatin
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PICK1 protein interacting with PRKCA 1
PLAT plasminogen activator, tissue
PLSCR4 phospholipid scramblase 4
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRSS53 protease, serine, 53
RAB3D RAB3D, member RAS oncogene family
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
REC8 REC8 meiotic recombination protein
RND1 Rho family GTPase 1
RNF39 ring finger protein 39
RPGRIP1L RPGRIP1-like
S100A9 S100 calcium binding protein A9
SEC14L2 SEC14-like 2 (S. cerevisiae)
SH2B3 SH2B adaptor protein 3
SLC17A2 solute carrier family 17, member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNTG1 syntrophin, gamma 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SPTBN2 spectrin, beta, non-erythrocytic 2
TBKBP1 TBK1 binding protein 1
TBX19 T-box 19
TMEM176A transmembrane protein 176A
TMPRSS4 transmembrane protease, serine 4
TOR4A torsin family 4, member A
TRAIP TRAF interacting protein
TUBB1 tubulin, beta 1 class VI
UNC93B1 unc-93 homolog B1 (C. elegans)
WLS wntless Wnt ligand secretion mediator
WNT2 wingless-type MMTV integration site family member 2
ZNF205 zinc finger protein 205
ZNF304 zinc finger protein 304
ZNF532 zinc finger protein 532
ZNF76 zinc finger protein 76