fisetin Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
Description A 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3' and 4'. (Chemical Entities of Biological Interest Ontology, CHEBI_42567)
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Genes

508 genes differentially expressed following the fisetin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 8.94297
CRYBB3 crystallin, beta B3 6.41642
FBXW2 F-box and WD repeat domain containing 2 5.71359
DENND2A DENN/MADD domain containing 2A 5.64551
ASCC3 activating signal cointegrator 1 complex subunit 3 5.59393
EBNA1BP2 EBNA1 binding protein 2 5.31588
PXN paxillin 5.16176
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 5.14503
NR5A1 nuclear receptor subfamily 5, group A, member 1 5.14109
TMEM74B transmembrane protein 74B 5.05351
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 4.96671
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 4.94658
FBXW10B F-box and WD repeat domain containing 10B 4.90815
EPB41L2 erythrocyte membrane protein band 4.1-like 2 4.84671
KCNIP1 Kv channel interacting protein 1 4.74246
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 4.72715
GRIK4 glutamate receptor, ionotropic, kainate 4 4.70969
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 4.70892
MPRIP myosin phosphatase Rho interacting protein 4.60382
APLP2 amyloid beta (A4) precursor-like protein 2 4.563
NCKAP1 NCK-associated protein 1 4.54297
COL4A1 collagen, type IV, alpha 1 4.52834
PDZD7 PDZ domain containing 7 4.49981
IQSEC1 IQ motif and Sec7 domain 1 4.47846
ITPK1 inositol-tetrakisphosphate 1-kinase 4.45855
FAM205BP transmembrane protein C9orf144B pseudogene 4.37751
PDGFA platelet-derived growth factor alpha polypeptide 4.36782
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 4.3667
PCSK7 proprotein convertase subtilisin/kexin type 7 4.32604
KRTAP1-3 keratin associated protein 1-3 4.28993
ADARB1 adenosine deaminase, RNA-specific, B1 4.28612
SOS2 son of sevenless homolog 2 (Drosophila) 4.26343
DUSP7 dual specificity phosphatase 7 4.26232
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 4.23988
FBXL18 F-box and leucine-rich repeat protein 18 4.2008
HKDC1 hexokinase domain containing 1 4.16133
FGF22 fibroblast growth factor 22 4.16027
B3GAT1 beta-1,3-glucuronyltransferase 1 4.15117
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 4.1185
SIGLEC8 sialic acid binding Ig-like lectin 8 4.08848
ACVRL1 activin A receptor type II-like 1 4.07706
NUAK1 NUAK family, SNF1-like kinase, 1 4.04759
SMTN smoothelin 4.03419
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 4.03351
SPRY4 sprouty homolog 4 (Drosophila) 4.01661
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 3.992
SOCS7 suppressor of cytokine signaling 7 3.9828
ETNK2 ethanolamine kinase 2 3.96388
HAPLN1 hyaluronan and proteoglycan link protein 1 3.96214
SAMD4A sterile alpha motif domain containing 4A 3.93223
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 3.87144
MID2 midline 2 3.87054
CADM4 cell adhesion molecule 4 3.86968
PCDHGA3 protocadherin gamma subfamily A, 3 3.86456
CEP112 centrosomal protein 112kDa 3.86018
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 3.85985
PPP4R1 protein phosphatase 4, regulatory subunit 1 3.83921
PACS2 phosphofurin acidic cluster sorting protein 2 3.83672
CC2D2B coiled-coil and C2 domain containing 2B 3.80961
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 3.78949
MICALL2 MICAL-like 2 3.77374
LINC00667 long intergenic non-protein coding RNA 667 3.75483
NUP62 nucleoporin 62kDa 3.74032
WWP1 WW domain containing E3 ubiquitin protein ligase 1 3.73876
SMG7 SMG7 nonsense mediated mRNA decay factor 3.72334
CRYBA4 crystallin, beta A4 3.71721
KCTD12 potassium channel tetramerization domain containing 12 3.7137
HPD 4-hydroxyphenylpyruvate dioxygenase 3.70934
SEH1L SEH1-like (S. cerevisiae) 3.70561
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 3.70523
DPYSL2 dihydropyrimidinase-like 2 3.70407
RHOBTB3 Rho-related BTB domain containing 3 3.70337
FAM168A family with sequence similarity 168, member A 3.70005
UCN urocortin 3.69581
HYAL4 hyaluronoglucosaminidase 4 3.69103
LGALS3 lectin, galactoside-binding, soluble, 3 3.68347
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 3.65702
FOXRED2 FAD-dependent oxidoreductase domain containing 2 3.65684
INO80D INO80 complex subunit D 3.64296
CENPB centromere protein B, 80kDa 3.64213
IL20RA interleukin 20 receptor, alpha 3.64105
RNF216 ring finger protein 216 3.6199
SHARPIN SHANK-associated RH domain interactor 3.61015
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 3.60888
GOLPH3 golgi phosphoprotein 3 (coat-protein) 3.6073
CDC25B cell division cycle 25B 3.60576
DPP4 dipeptidyl-peptidase 4 3.57499
IFT22 intraflagellar transport 22 3.57434
DPH2 DPH2 homolog (S. cerevisiae) 3.57176
NUP210 nucleoporin 210kDa 3.5679
NF2 neurofibromin 2 (merlin) 3.56496
SUN1 Sad1 and UNC84 domain containing 1 3.55723
ADAMTSL2 ADAMTS-like 2 3.54964
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 3.54779
KRTAP5-9 keratin associated protein 5-9 3.5414
FKBP1A FK506 binding protein 1A, 12kDa 3.53721
SMS spermine synthase 3.53456
PNPO pyridoxamine 5'-phosphate oxidase 3.53162
SACS sacsin molecular chaperone 3.52117
F2R coagulation factor II (thrombin) receptor 3.50663
WSCD1 WSC domain containing 1 3.50271
HK1 hexokinase 1 3.49844
BCL2L1 BCL2-like 1 3.49228
PAIP1 poly(A) binding protein interacting protein 1 3.47849
SCN1B sodium channel, voltage gated, type I beta subunit 3.47589
PCDH12 protocadherin 12 3.47208
DPYSL3 dihydropyrimidinase-like 3 3.45122
ACTL7B actin-like 7B 3.45067
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 3.43988
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 3.42661
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 3.42654
GNA12 guanine nucleotide binding protein (G protein) alpha 12 3.42073
MAPK7 mitogen-activated protein kinase 7 3.42065
NEUROG1 neurogenin 1 3.41972
PDLIM7 PDZ and LIM domain 7 (enigma) 3.41283
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 3.40972
OPRD1 opioid receptor, delta 1 3.40467
DOCK6 dedicator of cytokinesis 6 3.40411
OR2J2 olfactory receptor, family 2, subfamily J, member 2 3.40315
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 3.39496
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 3.38923
RAMP2 receptor (G protein-coupled) activity modifying protein 2 3.38362
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 3.38186
ONECUT2 one cut homeobox 2 3.38148
ZNF639 zinc finger protein 639 3.37532
TAGLN transgelin 3.3613
SH3GLB2 SH3-domain GRB2-like endophilin B2 3.36125
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 3.36028
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 3.36018
CELF3 CUGBP, Elav-like family member 3 3.35512
ADGRB3 adhesion G protein-coupled receptor B3 3.34351
PRPS2 phosphoribosyl pyrophosphate synthetase 2 3.34318
DRD2 dopamine receptor D2 3.33716
NCF2 neutrophil cytosolic factor 2 3.33229
PRKCA protein kinase C, alpha 3.33107
DOCK5 dedicator of cytokinesis 5 3.33002
GID4 GID complex subunit 4 3.32372
SH2B2 SH2B adaptor protein 2 3.32214
CCN2 cellular communication network factor 2 3.32144
FUBP3 far upstream element (FUSE) binding protein 3 3.31278
ZNF550 zinc finger protein 550 3.31272
UFM1 ubiquitin-fold modifier 1 3.31004
POU3F1 POU class 3 homeobox 1 3.30003
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 3.29884
ERVMER34-1 endogenous retrovirus group MER34, member 1 3.29301
KIF17 kinesin family member 17 3.29096
NECTIN1 nectin cell adhesion molecule 1 3.28867
ZNF696 zinc finger protein 696 3.28607
PTPN11 protein tyrosine phosphatase, non-receptor type 11 3.27981
HACD2 3-hydroxyacyl-CoA dehydratase 2 3.27788
CHD1 chromodomain helicase DNA binding protein 1 3.273
ERI3 ERI1 exoribonuclease family member 3 3.26863
ACSL1 acyl-CoA synthetase long-chain family member 1 3.26807
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 3.26358
EIF5B eukaryotic translation initiation factor 5B 3.26174
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 3.2592
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 3.25887
B3GAT3 beta-1,3-glucuronyltransferase 3 3.25835
HMHB1 histocompatibility (minor) HB-1 3.25672
KRT8 keratin 8, type II 3.25021
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 3.24942
TGFB1I1 transforming growth factor beta 1 induced transcript 1 3.24893
DENR density-regulated protein 3.24211
CTNND2 catenin (cadherin-associated protein), delta 2 3.239
DVL1 dishevelled segment polarity protein 1 3.23185
NOP56 NOP56 ribonucleoprotein 3.22857
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 3.22287
FAT2 FAT atypical cadherin 2 3.22063
GLS glutaminase 3.22055
PGAP6 post-GPI attachment to proteins 6 3.21831
TMPRSS2 transmembrane protease, serine 2 3.21746
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 3.21649
OSBPL7 oxysterol binding protein-like 7 3.21266
ITGA7 integrin, alpha 7 3.2126
PRDM5 PR domain containing 5 3.20912
NPPA natriuretic peptide A 3.20721
ZFP2 ZFP2 zinc finger protein 3.20538
GGT1 gamma-glutamyltransferase 1 3.20521
RAB3B RAB3B, member RAS oncogene family 3.19907
ATR ATR serine/threonine kinase 3.19585
CARD10 caspase recruitment domain family, member 10 3.19554
PHLDA3 pleckstrin homology-like domain, family A, member 3 3.19449
AMELY amelogenin, Y-linked 3.18973
PTPRA protein tyrosine phosphatase, receptor type, A 3.18956
GRK6 G protein-coupled receptor kinase 6 3.18812
POPDC2 popeye domain containing 2 3.18771
OSBPL10 oxysterol binding protein-like 10 3.18677
MAP1B microtubule-associated protein 1B 3.18002
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 3.1798
GJB4 gap junction protein, beta 4, 30.3kDa 3.17937
TEK TEK tyrosine kinase, endothelial 3.17715
SMG6 SMG6 nonsense mediated mRNA decay factor 3.17709
ETV3 ets variant 3 3.17533
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 3.17093
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 3.16873
INSL3 insulin-like 3 (Leydig cell) 3.16469
ATMIN ATM interactor 3.1639
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 3.16084
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 3.15983
TNIP1 TNFAIP3 interacting protein 1 3.15938
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 3.1549
TMEM131L transmembrane 131 like 3.15478
CDKL5 cyclin-dependent kinase-like 5 3.14421
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 3.14353
QKI QKI, KH domain containing, RNA binding 3.14045
MEGF8 multiple EGF-like-domains 8 3.14039
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 3.13262
COL4A2 collagen, type IV, alpha 2 3.13199
KANSL3 KAT8 regulatory NSL complex subunit 3 3.1289
SORBS3 sorbin and SH3 domain containing 3 3.12704
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 3.12112
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 3.11936
PCDHGC3 protocadherin gamma subfamily C, 3 3.11796
CSK c-src tyrosine kinase 3.11451
CAPRIN2 caprin family member 2 3.11165
DNAAF5 dynein, axonemal, assembly factor 5 3.11155
HES2 hes family bHLH transcription factor 2 3.10246
ZBTB7A zinc finger and BTB domain containing 7A 3.10089
VCL vinculin 3.1002
MIR9-1HG MIR9-1 host gene 3.09777
AEN apoptosis enhancing nuclease 3.09521
LGALS1 lectin, galactoside-binding, soluble, 1 3.0891
TCF7 transcription factor 7 (T-cell specific, HMG-box) 3.08329
AXL AXL receptor tyrosine kinase 3.07773
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 3.07523
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 3.0689
PGM5 phosphoglucomutase 5 3.06801
EFCC1 EF-hand and coiled-coil domain containing 1 3.0668
RAP1GAP2 RAP1 GTPase activating protein 2 3.06666
ZYX zyxin 3.06297
VIPR1 vasoactive intestinal peptide receptor 1 3.06175
SIRT5 sirtuin 5 3.05769
EBI3 Epstein-Barr virus induced 3 3.05144
ZNF358 zinc finger protein 358 3.04979
ADAM11 ADAM metallopeptidase domain 11 3.04877
ZIC4 Zic family member 4 3.04701
MAP3K3 mitogen-activated protein kinase kinase kinase 3 3.04454
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 3.04172
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 3.0377
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 3.03737
SLAMF1 signaling lymphocytic activation molecule family member 1 3.03684
PNPLA4 patatin-like phospholipase domain containing 4 3.03579
ADGRB2 adhesion G protein-coupled receptor B2 3.03357
PRLH prolactin releasing hormone 3.02766
NHLH2 nescient helix loop helix 2 3.02714
TAOK1 TAO kinase 1 3.02634
SFN stratifin 3.02617
TMPRSS5 transmembrane protease, serine 5 3.0258
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) 3.02578
FLNA filamin A, alpha 3.02064
SGSM2 small G protein signaling modulator 2 3.0205
CCL27 chemokine (C-C motif) ligand 27 3.01194
GRK4 G protein-coupled receptor kinase 4 3.01063
GALR1 galanin receptor 1 3.01008
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 3.00747
TRIM3 tripartite motif containing 3 3.00569
HEG1 heart development protein with EGF-like domains 1 3.0011

decreased expression

Symbol Name Standardized Value
MAGEL2 melanoma antigen family L2 -5.95885
ASCC1 activating signal cointegrator 1 complex subunit 1 -5.46261
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 -5.30808
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase -5.22707
PRSS16 protease, serine, 16 (thymus) -4.94565
ZFP36L2 ZFP36 ring finger protein-like 2 -4.90746
TGDS TDP-glucose 4,6-dehydratase -4.89931
PGGT1B protein geranylgeranyltransferase type I, beta subunit -4.71123
OR7A5 olfactory receptor, family 7, subfamily A, member 5 -4.56342
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa -4.54893
STMN1 stathmin 1 -4.51011
POT1 protection of telomeres 1 -4.47458
ELF1 E74-like factor 1 (ets domain transcription factor) -4.4357
MTO1 mitochondrial tRNA translation optimization 1 -4.43511
RIT1 Ras-like without CAAX 1 -4.39982
PFDN5 prefoldin subunit 5 -4.28707
SYF2 SYF2 pre-mRNA-splicing factor -4.27497
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -4.25404
DPH5 diphthamide biosynthesis 5 -4.234
RPL11 ribosomal protein L11 -4.23019
RNF130 ring finger protein 130 -4.2266
CAND1 cullin-associated and neddylation-dissociated 1 -4.16118
AGTR2 angiotensin II receptor, type 2 -4.15909
SLC35B1 solute carrier family 35, member B1 -4.15425
PARP16 poly (ADP-ribose) polymerase family, member 16 -4.12181
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -4.12163
MYEF2 myelin expression factor 2 -4.12065
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -4.11419
CPA3 carboxypeptidase A3 (mast cell) -4.10369
COPS2 COP9 signalosome subunit 2 -4.00924
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A -4.00837
MDM1 Mdm1 nuclear protein homolog (mouse) -3.99298
RAD21L1 RAD21-like 1 (S. pombe) -3.98997
MTUS2 microtubule associated tumor suppressor candidate 2 -3.98811
PELO pelota homolog (Drosophila) -3.97805
GMCL1 germ cell-less, spermatogenesis associated 1 -3.93145
CCNH cyclin H -3.92456
CNPY2 canopy FGF signaling regulator 2 -3.91148
ASNSD1 asparagine synthetase domain containing 1 -3.90802
WBP1L WW domain binding protein 1-like -3.89794
MED8 mediator complex subunit 8 -3.89227
THAP3 THAP domain containing, apoptosis associated protein 3 -3.89179
MYB v-myb avian myeloblastosis viral oncogene homolog -3.88273
EHF ets homologous factor -3.87436
NR1H3 nuclear receptor subfamily 1, group H, member 3 -3.84686
FGF23 fibroblast growth factor 23 -3.83696
PGD phosphogluconate dehydrogenase -3.83628
COL15A1 collagen, type XV, alpha 1 -3.83352
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -3.80847
CD300C CD300c molecule -3.80136
KRCC1 lysine-rich coiled-coil 1 -3.79614
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -3.78569
LARP7 La ribonucleoprotein domain family, member 7 -3.76031
MFSD1 major facilitator superfamily domain containing 1 -3.75625
E2F6 E2F transcription factor 6 -3.74659
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 -3.72932
ZNF253 zinc finger protein 253 -3.72773
USP16 ubiquitin specific peptidase 16 -3.70981
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -3.70104
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -3.70033
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) -3.70027
TMEM19 transmembrane protein 19 -3.69123
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 -3.64253
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -3.63944
BORA bora, aurora kinase A activator -3.63927
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -3.63596
ABITRAM actin binding transcription modulator -3.60867
FNTA farnesyltransferase, CAAX box, alpha -3.60533
ZNHIT3 zinc finger, HIT-type containing 3 -3.6022
TFG TRK-fused gene -3.60192
ST7 suppression of tumorigenicity 7 -3.60135
TTC17 tetratricopeptide repeat domain 17 -3.59181
RPA2 replication protein A2, 32kDa -3.57393
LINC00472 long intergenic non-protein coding RNA 472 -3.57251
C3AR1 complement component 3a receptor 1 -3.56946
MRPL35 mitochondrial ribosomal protein L35 -3.56607
RSRC2 arginine/serine-rich coiled-coil 2 -3.5516
SPP1 secreted phosphoprotein 1 -3.53874
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) -3.53194
IQCB1 IQ motif containing B1 -3.52383
PCID2 PCI domain containing 2 -3.51204
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -3.51067
ACOT13 acyl-CoA thioesterase 13 -3.5076
PDIA2 protein disulfide isomerase family A, member 2 -3.5033
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -3.50303
RAB13 RAB13, member RAS oncogene family -3.50094
NFYA nuclear transcription factor Y, alpha -3.49739
GABPA GA binding protein transcription factor, alpha subunit 60kDa -3.4939
TM2D1 TM2 domain containing 1 -3.48826
ZNF516 zinc finger protein 516 -3.48798
CASP4 caspase 4, apoptosis-related cysteine peptidase -3.47571
ZNF395 zinc finger protein 395 -3.47473
MXD1 MAX dimerization protein 1 -3.47426
ZBTB5 zinc finger and BTB domain containing 5 -3.46922
ZSCAN31 zinc finger and SCAN domain containing 31 -3.46799
NT5C2 5'-nucleotidase, cytosolic II -3.46351
RBM4B RNA binding motif protein 4B -3.4487
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -3.44824
NPY1R neuropeptide Y receptor Y1 -3.44737
BRAF B-Raf proto-oncogene, serine/threonine kinase -3.44577
USP15 ubiquitin specific peptidase 15 -3.4407
MRPL49 mitochondrial ribosomal protein L49 -3.43807
IQCG IQ motif containing G -3.43454
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.43158
RPL35A ribosomal protein L35a -3.41657
RS1 retinoschisin 1 -3.41314
TPRKB TP53RK binding protein -3.41015
BANP BTG3 associated nuclear protein -3.40224
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa -3.3989
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.39609
RPS6 ribosomal protein S6 -3.39373
LETMD1 LETM1 domain containing 1 -3.39153
MFAP1 microfibrillar-associated protein 1 -3.39122
PEX1 peroxisomal biogenesis factor 1 -3.38773
MXI1 MAX interactor 1, dimerization protein -3.38736
EFHC2 EF-hand domain (C-terminal) containing 2 -3.38553
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 -3.38312
THAP1 THAP domain containing, apoptosis associated protein 1 -3.3776
SOX30 SRY (sex determining region Y)-box 30 -3.37412
GPN2 GPN-loop GTPase 2 -3.36955
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) -3.36695
TLR8 toll-like receptor 8 -3.36084
SIAH2 siah E3 ubiquitin protein ligase 2 -3.35954
RPL17 ribosomal protein L17 -3.35481
CDC16 cell division cycle 16 -3.35413
FMOD fibromodulin -3.35152
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional) -3.34147
ARHGAP24 Rho GTPase activating protein 24 -3.33481
ASB7 ankyrin repeat and SOCS box containing 7 -3.33447
CRELD1 cysteine-rich with EGF-like domains 1 -3.33201
DGUOK deoxyguanosine kinase -3.33042
ERLIN1 ER lipid raft associated 1 -3.32893
GLA galactosidase, alpha -3.31289
MPC2 mitochondrial pyruvate carrier 2 -3.31039
GABPB1 GA binding protein transcription factor, beta subunit 1 -3.30984
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -3.30971
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) -3.30908
EIF1B eukaryotic translation initiation factor 1B -3.30739
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -3.30388
AP3B1 adaptor-related protein complex 3, beta 1 subunit -3.30141
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -3.29592
JAK2 Janus kinase 2 -3.28445
ZNF184 zinc finger protein 184 -3.27426
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 -3.27243
LMBRD1 LMBR1 domain containing 1 -3.27168
LHFPL2 lipoma HMGIC fusion partner-like 2 -3.26936
PLPP1 phospholipid phosphatase 1 -3.25843
NDN necdin, melanoma antigen (MAGE) family member -3.25342
ZNF552 zinc finger protein 552 -3.25161
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 -3.24353
ERCC5 excision repair cross-complementation group 5 -3.24287
MAPK14 mitogen-activated protein kinase 14 -3.24238
LIG4 ligase IV, DNA, ATP-dependent -3.23904
TRIP4 thyroid hormone receptor interactor 4 -3.23042
C1ORF112 chromosome 1 open reading frame 112 -3.22512
JUN jun proto-oncogene -3.22483
ABI3BP ABI family, member 3 (NESH) binding protein -3.22403
RBM48 RNA binding motif protein 48 -3.22192
PPIA peptidylprolyl isomerase A (cyclophilin A) -3.22156
EIF3I eukaryotic translation initiation factor 3, subunit I -3.21835
DNAAF1 dynein, axonemal, assembly factor 1 -3.21626
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 -3.21571
OARD1 O-acyl-ADP-ribose deacylase 1 -3.20954
MKS1 Meckel syndrome, type 1 -3.20279
TRIM48 tripartite motif containing 48 -3.19832
RNFT1 ring finger protein, transmembrane 1 -3.19525
LRIF1 ligand dependent nuclear receptor interacting factor 1 -3.19125
ZNF451 zinc finger protein 451 -3.18811
RNF7 ring finger protein 7 -3.18746
CFAP20 cilia and flagella associated protein 20 -3.18702
ZNF280A zinc finger protein 280A -3.18593
TANK TRAF family member-associated NFKB activator -3.18513
TLR1 toll-like receptor 1 -3.18475
CASP9 caspase 9, apoptosis-related cysteine peptidase -3.18425
TMPO thymopoietin -3.18118
ZNF212 zinc finger protein 212 -3.18007
COPS4 COP9 signalosome subunit 4 -3.17352
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -3.17342
MRPL40 mitochondrial ribosomal protein L40 -3.17336
DDIT4 DNA-damage-inducible transcript 4 -3.1709
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) -3.16799
ARL3 ADP-ribosylation factor-like 3 -3.16361
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -3.1628
SIGLEC6 sialic acid binding Ig-like lectin 6 -3.15221
LRRC42 leucine rich repeat containing 42 -3.1493
RPL22 ribosomal protein L22 -3.14743
MBD4 methyl-CpG binding domain protein 4 -3.14628
ZMYM5 zinc finger, MYM-type 5 -3.14371
RPS8 ribosomal protein S8 -3.14194
EAF2 ELL associated factor 2 -3.14152
CALU calumenin -3.14015
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma -3.13862
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 -3.1378
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -3.13405
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) -3.13249
CNTRL centriolin -3.12703
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -3.12674
RESF1 retroelement silencing factor 1 -3.126
NELFA negative elongation factor complex member A -3.12411
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -3.12278
KLHDC10 kelch domain containing 10 -3.11782
RPS26 ribosomal protein S26 -3.11756
STXBP6 syntaxin binding protein 6 (amisyn) -3.1166
MYCBP MYC binding protein -3.11447
DUSP1 dual specificity phosphatase 1 -3.11396
TXNIP thioredoxin interacting protein -3.107
PUM1 pumilio RNA-binding family member 1 -3.10453
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -3.10254
HSPB1 heat shock 27kDa protein 1 -3.10202
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) -3.0977
FAM149A family with sequence similarity 149, member A -3.09485
TSG101 tumor susceptibility 101 -3.09098
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.09095
RPL23A ribosomal protein L23a -3.08818
TOX4 TOX high mobility group box family member 4 -3.08233
NSD3 nuclear receptor binding SET domain protein 3 -3.07949
MARCHF7 membrane associated ring-CH-type finger 7 -3.07851
ADAM28 ADAM metallopeptidase domain 28 -3.07692
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI -3.07334
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -3.07142
DBT dihydrolipoamide branched chain transacylase E2 -3.07142
ACP5 acid phosphatase 5, tartrate resistant -3.05944
ELP3 elongator acetyltransferase complex subunit 3 -3.05804
AGBL2 ATP/GTP binding protein-like 2 -3.05678
MAML3 mastermind-like 3 (Drosophila) -3.05319
PPP1R8 protein phosphatase 1, regulatory subunit 8 -3.05084
DGKG diacylglycerol kinase, gamma 90kDa -3.04851
CDC37L1 cell division cycle 37-like 1 -3.04708
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -3.04676
BET1 Bet1 golgi vesicular membrane trafficking protein -3.04367
ITM2C integral membrane protein 2C -3.03728
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -3.03644
NSUN3 NOP2/Sun domain family, member 3 -3.03456
KCNK5 potassium channel, two pore domain subfamily K, member 5 -3.03333
GPR162 G protein-coupled receptor 162 -3.03155
SPATA6L spermatogenesis associated 6-like -3.03134
TM6SF1 transmembrane 6 superfamily member 1 -3.02705
APTX aprataxin -3.02576
UQCRC2 ubiquinol-cytochrome c reductase core protein II -3.02468
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -3.02184
DLK1 delta-like 1 homolog (Drosophila) -3.0179
CRYZL1 crystallin, zeta (quinone reductase)-like 1 -3.01699
SNIP1 Smad nuclear interacting protein 1 -3.01437
DNAI1 dynein, axonemal, intermediate chain 1 -3.01156
NCK1 NCK adaptor protein 1 -3.01049
STX17 syntaxin 17 -3.01028
TGS1 trimethylguanosine synthase 1 -3.00954
MRPL11 mitochondrial ribosomal protein L11 -3.00634
CCL7 chemokine (C-C motif) ligand 7 -3.00624
RAB20 RAB20, member RAS oncogene family -3.00365
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle -3.00273