flap endonuclease activity Gene Set

Dataset GO Molecular Function Annotations 2023
Category structural or functional annotations
Type biological process
Description Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis. (Gene Ontology, GO_0048256)
External Link http://amigo.geneontology.org/amigo/term/GO:0048256
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Genes

7 genes performing the flap endonuclease activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

Symbol Name
DNA2 DNA replication helicase/nuclease 2
EXO1 exonuclease 1
FEN1 flap structure-specific endonuclease 1
FSCN1 fascin actin-bundling protein 1
GEN1 GEN1 Holliday junction 5' flap endonuclease
MUS81 MUS81 structure-specific endonuclease subunit
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)