flavoxate-5427 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the flavoxate-5427 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ACRV1 acrosomal vesicle protein 1
ADAM22 ADAM metallopeptidase domain 22
ADGRG1 adhesion G protein-coupled receptor G1
AMELY amelogenin, Y-linked
AMPD1 adenosine monophosphate deaminase 1
APOC1 apolipoprotein C-I
ARHGAP1 Rho GTPase activating protein 1
BAHCC1 BAH domain and coiled-coil containing 1
BIN1 bridging integrator 1
BLNK B-cell linker
BMP2 bone morphogenetic protein 2
C14ORF79 chromosome 14 open reading frame 79
CALD1 caldesmon 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCR1 chemokine (C-C motif) receptor 1
CD48 CD48 molecule
CLCN4 chloride channel, voltage-sensitive 4
COL1A1 collagen, type I, alpha 1
COL4A2 collagen, type IV, alpha 2
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DOK2 docking protein 2, 56kDa
DPF1 D4, zinc and double PHD fingers family 1
DPF3 D4, zinc and double PHD fingers, family 3
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EBF2 early B-cell factor 2
EDNRA endothelin receptor type A
EML2 echinoderm microtubule associated protein like 2
FAXDC2 fatty acid hydroxylase domain containing 2
FCMR Fc fragment of IgM receptor
FOXG1 forkhead box G1
FSTL1 follistatin-like 1
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GLIPR1 GLI pathogenesis-related 1
GRM1 glutamate receptor, metabotropic 1
HCG4 HLA complex group 4 (non-protein coding)
HLF hepatic leukemia factor
HOXD1 homeobox D1
HSPA12A heat shock 70kDa protein 12A
IGFBP3 insulin-like growth factor binding protein 3
ITFG2 integrin alpha FG-GAP repeat containing 2
JMJD4 jumonji domain containing 4
KDM8 lysine (K)-specific demethylase 8
KLF12 Kruppel-like factor 12
KLK2 kallikrein-related peptidase 2
KREMEN2 kringle containing transmembrane protein 2
KRT31 keratin 31, type I
LGALS8 lectin, galactoside-binding, soluble, 8
LIFR leukemia inhibitory factor receptor alpha
LMF2 lipase maturation factor 2
LOC729164 hCG1732469
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYZL6 lysozyme-like 6
MAP4 microtubule-associated protein 4
MOG myelin oligodendrocyte glycoprotein
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTA1 metastasis associated 1
MTCP1 mature T-cell proliferation 1
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NF1 neurofibromin 1
NGDN neuroguidin, EIF4E binding protein
NXPH3 neurexophilin 3
P3H2 prolyl 3-hydroxylase 2
PAPOLA poly(A) polymerase alpha
PCLO piccolo presynaptic cytomatrix protein
PGK2 phosphoglycerate kinase 2
PHEX phosphate regulating endopeptidase homolog, X-linked
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFPL1S RFPL1 antisense RNA 1
RPS4Y1 ribosomal protein S4, Y-linked 1
RRBP1 ribosome binding protein 1
RUNX3 runt-related transcription factor 3
RXRB retinoid X receptor, beta
SCAI suppressor of cancer cell invasion
SH3BP2 SH3-domain binding protein 2
SPTAN1 spectrin, alpha, non-erythrocytic 1
STYK1 serine/threonine/tyrosine kinase 1
SYT5 synaptotagmin V
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
THBS4 thrombospondin 4
TMEM40 transmembrane protein 40
TRH thyrotropin-releasing hormone
TRIM29 tripartite motif containing 29
USP2 ubiquitin specific peptidase 2
UTRN utrophin
WSB1 WD repeat and SOCS box containing 1
YPEL1 yippee-like 1 (Drosophila)
YTHDC2 YTH domain containing 2
ZFP64 ZFP64 zinc finger protein
ZNF76 zinc finger protein 76
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ADCY7 adenylate cyclase 7
ADGRG2 adhesion G protein-coupled receptor G2
ANKRD40 ankyrin repeat domain 40
APOD apolipoprotein D
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARMC4 armadillo repeat containing 4
ATP10D ATPase, class V, type 10D
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
C11ORF80 chromosome 11 open reading frame 80
C1ORF159 chromosome 1 open reading frame 159
CAPN5 calpain 5
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC71 coiled-coil domain containing 71
CD83 CD83 molecule
CFD complement factor D (adipsin)
CLCF1 cardiotrophin-like cytokine factor 1
CLCN2 chloride channel, voltage-sensitive 2
CNR2 cannabinoid receptor 2 (macrophage)
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRABP1 cellular retinoic acid binding protein 1
CRY2 cryptochrome circadian clock 2
CTSF cathepsin F
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DBF4B DBF4 zinc finger B
DGAT1 diacylglycerol O-acyltransferase 1
DSCAM Down syndrome cell adhesion molecule
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
EXO5 exonuclease 5
FBXO31 F-box protein 31
FBXO4 F-box protein 4
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GPATCH2L G patch domain containing 2-like
GSTA4 glutathione S-transferase alpha 4
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HHAT hedgehog acyltransferase
HIST1H2AK histone cluster 1, H2ak
HIST1H2AL histone cluster 1, H2al
HIST1H4A histone cluster 1, H4a
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HOXA4 homeobox A4
HPN hepsin
IGFBP6 insulin-like growth factor binding protein 6
IL17RA interleukin 17 receptor A
INO80D INO80 complex subunit D
INPP5J inositol polyphosphate-5-phosphatase J
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCTD7 potassium channel tetramerization domain containing 7
KLF7 Kruppel-like factor 7 (ubiquitous)
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT13 keratin 13, type I
LAMC3 laminin, gamma 3
LEFTY1 left-right determination factor 1
LIN7B lin-7 homolog B (C. elegans)
LMNB1 lamin B1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MATK megakaryocyte-associated tyrosine kinase
MRPS18C mitochondrial ribosomal protein S18C
MVD mevalonate (diphospho) decarboxylase
NME5 NME/NM23 family member 5
NOL10 nucleolar protein 10
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PDE12 phosphodiesterase 12
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POLL polymerase (DNA directed), lambda
PRKCE protein kinase C, epsilon
PSG4 pregnancy specific beta-1-glycoprotein 4
RIN1 Ras and Rab interactor 1
ROM1 retinal outer segment membrane protein 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUSC2 RUN and SH3 domain containing 2
S100A9 S100 calcium binding protein A9
SBNO2 strawberry notch homolog 2 (Drosophila)
SENP7 SUMO1/sentrin specific peptidase 7
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIRT6 sirtuin 6
SIX1 SIX homeobox 1
SMA4 glucuronidase, beta pseudogene
SPON2 spondin 2, extracellular matrix protein
SRPX sushi-repeat containing protein, X-linked
SYBU syntabulin (syntaxin-interacting)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK1 TAO kinase 1
TARP TCR gamma alternate reading frame protein
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRIM21 tripartite motif containing 21
TSGA10 testis specific, 10
TSNAXIP1 translin-associated factor X interacting protein 1
TTC9 tetratricopeptide repeat domain 9
TWF2 twinfilin actin binding protein 2
TWISTNB TWIST neighbor
WLS wntless Wnt ligand secretion mediator
ZFP37 ZFP37 zinc finger protein
ZNF480 zinc finger protein 480