| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the flecainide-2557 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANO2 | anoctamin 2, calcium activated chloride channel |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATP9B | ATPase, class II, type 9B |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF68 | chromosome 1 open reading frame 68 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CADM4 | cell adhesion molecule 4 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLEC2D | C-type lectin domain family 2, member D |
| COL9A3 | collagen, type IX, alpha 3 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSN3 | casein kappa |
| CSNK1E | casein kinase 1, epsilon |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EDNRA | endothelin receptor type A |
| EMILIN2 | elastin microfibril interfacer 2 |
| EMP1 | epithelial membrane protein 1 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
| ESR1 | estrogen receptor 1 |
| FADS3 | fatty acid desaturase 3 |
| GK3P | glycerol kinase 3 pseudogene |
| GMPR | guanosine monophosphate reductase |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GRHL2 | grainyhead-like 2 (Drosophila) |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HOMER3 | homer scaffolding protein 3 |
| HOXA10 | homeobox A10 |
| HPSE | heparanase |
| ICAM1 | intercellular adhesion molecule 1 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KSR1 | kinase suppressor of ras 1 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LTB4R | leukotriene B4 receptor |
| MEGF8 | multiple EGF-like-domains 8 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MPDZ | multiple PDZ domain protein |
| MRC2 | mannose receptor, C type 2 |
| MYOF | myoferlin |
| MYOZ2 | myozenin 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| PDE10A | phosphodiesterase 10A |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PKP4 | plakophilin 4 |
| PLP1 | proteolipid protein 1 |
| PLSCR3 | phospholipid scramblase 3 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POLR3F | polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRSS21 | protease, serine, 21 (testisin) |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RGS10 | regulator of G-protein signaling 10 |
| RPL13 | ribosomal protein L13 |
| RRAGB | Ras-related GTP binding B |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMAD5-AS1 | SMAD5 antisense RNA 1 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| STOML1 | stomatin (EPB72)-like 1 |
| TAGLN3 | transgelin 3 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| THSD7A | thrombospondin, type I, domain containing 7A |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UBOX5 | U-box domain containing 5 |
| USP6NL | USP6 N-terminal like |
| YOD1 | YOD1 deubiquitinase |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF155 | zinc finger protein 155 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ADGB | androglobin |
| AIRE | autoimmune regulator |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APH1B | APH1B gamma secretase subunit |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BMP15 | bone morphogenetic protein 15 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CBX8 | chromobox homolog 8 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CFAP45 | cilia and flagella associated protein 45 |
| CHMP7 | charged multivesicular body protein 7 |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CLEC4A | C-type lectin domain family 4, member A |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CRYGC | crystallin, gamma C |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DOC2A | double C2-like domains, alpha |
| DOK3 | docking protein 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM13C | family with sequence similarity 13, member C |
| FBXO40 | F-box protein 40 |
| FGF23 | fibroblast growth factor 23 |
| FLT4 | fms-related tyrosine kinase 4 |
| FMOD | fibromodulin |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR68 | G protein-coupled receptor 68 |
| GRPR | gastrin-releasing peptide receptor |
| GSTT1 | glutathione S-transferase theta 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3B | histone cluster 1, H3b |
| HOXC8 | homeobox C8 |
| HRH2 | histamine receptor H2 |
| HSPA2 | heat shock 70kDa protein 2 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NINJ2 | ninjurin 2 |
| NOL10 | nucleolar protein 10 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCBP4 | poly(rC) binding protein 4 |
| PDLIM1 | PDZ and LIM domain 1 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PROCR | protein C receptor, endothelial |
| PRR14L | proline rich 14-like |
| PRR7 | proline rich 7 (synaptic) |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RNF122 | ring finger protein 122 |
| RPP38 | ribonuclease P/MRP 38kDa subunit |
| S100A12 | S100 calcium binding protein A12 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SH2D4A | SH2 domain containing 4A |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SLC26A4 | solute carrier family 26 (anion exchanger), member 4 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| SPAG1 | sperm associated antigen 1 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| SYTL2 | synaptotagmin-like 2 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TPM3 | tropomyosin 3 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| USB1 | U6 snRNA biogenesis 1 |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF813 | zinc finger protein 813 |
