| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the flecainide-3843 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM8 | ADAM metallopeptidase domain 8 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ANGPTL2 | angiopoietin-like 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ATP11A | ATPase, class VI, type 11A |
| ATP9B | ATPase, class II, type 9B |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BTG2 | BTG family, member 2 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCNJL | cyclin J-like |
| CD34 | CD34 molecule |
| CDRT1 | CMT1A duplicated region transcript 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DAPK3 | death-associated protein kinase 3 |
| DST | dystonin |
| DUSP1 | dual specificity phosphatase 1 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 |
| EML2 | echinoderm microtubule associated protein like 2 |
| EPHB2 | EPH receptor B2 |
| ERCC2 | excision repair cross-complementation group 2 |
| ESR1 | estrogen receptor 1 |
| EZR | ezrin |
| FUS | FUS RNA binding protein |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GPR176 | G protein-coupled receptor 176 |
| GPR182 | G protein-coupled receptor 182 |
| GSN | gelsolin |
| HEMK1 | HemK methyltransferase family member 1 |
| HIC2 | hypermethylated in cancer 2 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IDS | iduronate 2-sulfatase |
| IFT27 | intraflagellar transport 27 |
| IL6ST | interleukin 6 signal transducer |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 |
| KITLG | KIT ligand |
| KLF13 | Kruppel-like factor 13 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAPK14 | mitogen-activated protein kinase 14 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| NDRG2 | NDRG family member 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEU3 | sialidase 3 (membrane sialidase) |
| NF1 | neurofibromin 1 |
| NOL12 | nucleolar protein 12 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NRG1 | neuregulin 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NUP188 | nucleoporin 188kDa |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PEG10 | paternally expressed 10 |
| PHF3 | PHD finger protein 3 |
| POM121 | POM121 transmembrane nucleoporin |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PVR | poliovirus receptor |
| RBM5 | RNA binding motif protein 5 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RRBP1 | ribosome binding protein 1 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SP1 | Sp1 transcription factor |
| SPEG | SPEG complex locus |
| SPRR1A | small proline-rich protein 1A |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STXBP6 | syntaxin binding protein 6 (amisyn) |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TDRD12 | tudor domain containing 12 |
| TFR2 | transferrin receptor 2 |
| THBS1 | thrombospondin 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TOB2 | transducer of ERBB2, 2 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRAF4 | TNF receptor-associated factor 4 |
| TRIM10 | tripartite motif containing 10 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TSC22D2 | TSC22 domain family, member 2 |
| WASL | Wiskott-Aldrich syndrome-like |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF480 | zinc finger protein 480 |
| ZNF506 | zinc finger protein 506 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| AFAP1 | actin filament associated protein 1 |
| ALOX15 | arachidonate 15-lipoxygenase |
| AMH | anti-Mullerian hormone |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C4BPA | complement component 4 binding protein, alpha |
| CALML5 | calmodulin-like 5 |
| CCDC71 | coiled-coil domain containing 71 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CFD | complement factor D (adipsin) |
| CSTA | cystatin A (stefin A) |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| CUL9 | cullin 9 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DMTN | dematin actin binding protein |
| DNM1 | dynamin 1 |
| DOC2A | double C2-like domains, alpha |
| DUSP2 | dual specificity phosphatase 2 |
| EMID1 | EMI domain containing 1 |
| FAM53B | family with sequence similarity 53, member B |
| FBXO2 | F-box protein 2 |
| FBXO31 | F-box protein 31 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGF4 | fibroblast growth factor 4 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FLJ22184 | |
| FOXD1 | forkhead box D1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GK3P | glycerol kinase 3 pseudogene |
| HDAC5 | histone deacetylase 5 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H4C | histone cluster 1, H4c |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFT54 | intraflagellar transport 54 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMNB1 | lamin B1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LOC729164 | hCG1732469 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLCD1 | phospholipase C, delta 1 |
| RAB33B | RAB33B, member RAS oncogene family |
| RNF123 | ring finger protein 123 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| RUNDC3B | RUN domain containing 3B |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SDC3 | syndecan 3 |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMIM14 | small integral membrane protein 14 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| TCTN2 | tectonic family member 2 |
| TEX40 | testis expressed 40 |
| TFF2 | trefoil factor 2 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM104 | transmembrane protein 104 |
| TOR4A | torsin family 4, member A |
| TRAF5 | TNF receptor-associated factor 5 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRIM21 | tripartite motif containing 21 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TTBK2 | tau tubulin kinase 2 |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| TYRP1 | tyrosinase-related protein 1 |
| UBQLN4 | ubiquilin 4 |
| USP19 | ubiquitin specific peptidase 19 |
| WDR25 | WD repeat domain 25 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF286A | zinc finger protein 286A |
| ZNF358 | zinc finger protein 358 |
| ZNF484 | zinc finger protein 484 |
| ZNF639 | zinc finger protein 639 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
