| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the flecainide-3937 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AFF2 | AF4/FMR2 family, member 2 |
| AGFG1 | ArfGAP with FG repeats 1 |
| ANKRD12 | ankyrin repeat domain 12 |
| AP4S1 | adaptor-related protein complex 4, sigma 1 subunit |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ARMC4 | armadillo repeat containing 4 |
| ATG10 | autophagy related 10 |
| ATP10B | ATPase, class V, type 10B |
| AURKA | aurora kinase A |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| C1ORF95 | chromosome 1 open reading frame 95 |
| CAV2 | caveolin 2 |
| CD58 | CD58 molecule |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| CPB2 | carboxypeptidase B2 (plasma) |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| E2F5 | E2F transcription factor 5, p130-binding |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 |
| EIF5B | eukaryotic translation initiation factor 5B |
| ELN | elastin |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ETV1 | ets variant 1 |
| EZR | ezrin |
| FABP7 | fatty acid binding protein 7, brain |
| FGFR2 | fibroblast growth factor receptor 2 |
| FLOT1 | flotillin 1 |
| GFI1 | growth factor independent 1 transcription repressor |
| GP6 | glycoprotein VI (platelet) |
| GPX5 | glutathione peroxidase 5 |
| GRSF1 | G-rich RNA sequence binding factor 1 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| IFNA10 | interferon, alpha 10 |
| IL2RB | interleukin 2 receptor, beta |
| ING2 | inhibitor of growth family, member 2 |
| IQCH | IQ motif containing H |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIAA1109 | KIAA1109 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LIFR | leukemia inhibitory factor receptor alpha |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOXL3 | lysyl oxidase-like 3 |
| MAGEA6 | melanoma antigen family A6 |
| MEP1B | meprin A, beta |
| MUC8 | mucin 8 |
| NCKAP1 | NCK-associated protein 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PGK1 | phosphoglycerate kinase 1 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PMCH | pro-melanin-concentrating hormone |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PRO2012 | uncharacterized protein PRO2012 |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| PRRC2C | proline-rich coiled-coil 2C |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RAB2A | RAB2A, member RAS oncogene family |
| RASA3 | RAS p21 protein activator 3 |
| RBP4 | retinol binding protein 4, plasma |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RHEB | Ras homolog enriched in brain |
| RPAIN | RPA interacting protein |
| RPL14 | ribosomal protein L14 |
| SAFB | scaffold attachment factor B |
| SH2D3A | SH2 domain containing 3A |
| SIKE1 | suppressor of IKBKE 1 |
| SPAG8 | sperm associated antigen 8 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| THAP9 | THAP domain containing 9 |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 |
| TRAM1 | translocation associated membrane protein 1 |
| TSHR | thyroid stimulating hormone receptor |
| TWF1 | twinfilin actin binding protein 1 |
| TXN | thioredoxin |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 |
| UPK3A | uroplakin 3A |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| VDAC3 | voltage-dependent anion channel 3 |
| WAPAL | wings apart-like homolog (Drosophila) |
| WSB1 | WD repeat and SOCS box containing 1 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ACTL8 | actin-like 8 |
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| AHSP | alpha hemoglobin stabilizing protein |
| AIRE | autoimmune regulator |
| ANXA2P1 | annexin A2 pseudogene 1 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| B9D2 | B9 protein domain 2 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDHR2 | cadherin-related family member 2 |
| CDON | cell adhesion associated, oncogene regulated |
| CEP170B | centrosomal protein 170B |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLEC4E | C-type lectin domain family 4, member E |
| CLIC2 | chloride intracellular channel 2 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CNTFR | ciliary neurotrophic factor receptor |
| CRMP1 | collapsin response mediator protein 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DMTN | dematin actin binding protein |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DRD1 | dopamine receptor D1 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DUSP9 | dual specificity phosphatase 9 |
| EFNB3 | ephrin-B3 |
| EMP3 | epithelial membrane protein 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM155B | family with sequence similarity 155, member B |
| FLJ22184 | |
| FLT4 | fms-related tyrosine kinase 4 |
| FRMD1 | FERM domain containing 1 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPR1 | G protein-coupled receptor 1 |
| GRPR | gastrin-releasing peptide receptor |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HIST1H3B | histone cluster 1, H3b |
| HMOX1 | heme oxygenase 1 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| HYI | hydroxypyruvate isomerase (putative) |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| ITGA10 | integrin, alpha 10 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KLF8 | Kruppel-like factor 8 |
| KLHL25 | kelch-like family member 25 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LMO7 | LIM domain 7 |
| MAOB | monoamine oxidase B |
| MAPK7 | mitogen-activated protein kinase 7 |
| MID1IP1 | MID1 interacting protein 1 |
| MUC3A | mucin 3A, cell surface associated |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPY | neuropeptide Y |
| OCA2 | oculocutaneous albinism II |
| OLFML2A | olfactomedin-like 2A |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIPOX | pipecolic acid oxidase |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SLC17A2 | solute carrier family 17, member 2 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSTR4 | somatostatin receptor 4 |
| TAOK1 | TAO kinase 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TBC1D19 | TBC1 domain family, member 19 |
| TLN1 | talin 1 |
| TMEM121 | transmembrane protein 121 |
| TMEM8B | transmembrane protein 8B |
| TNS2 | tensin 2 |
| TRAIP | TRAF interacting protein |
| TRIM21 | tripartite motif containing 21 |
| TSC22D4 | TSC22 domain family, member 4 |
| UPK2 | uroplakin 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VASP | vasodilator-stimulated phosphoprotein |
| XYLT2 | xylosyltransferase II |
| ZNF197 | zinc finger protein 197 |
| ZNF205 | zinc finger protein 205 |
| ZNF747 | zinc finger protein 747 |
| ZXDB | zinc finger, X-linked, duplicated B |
