| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the flecainide-4318 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADCY1 | adenylate cyclase 1 (brain) |
| ADD2 | adducin 2 (beta) |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| BCL2L1 | BCL2-like 1 |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| COL6A1 | collagen, type VI, alpha 1 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
| CYTH4 | cytohesin 4 |
| DGKA | diacylglycerol kinase, alpha 80kDa |
| DKFZP434C153 | DKFZP434C153 protein |
| DLX2 | distal-less homeobox 2 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DTNA | dystrobrevin, alpha |
| EGFR | epidermal growth factor receptor |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXO22 | F-box protein 22 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR137 | G protein-coupled receptor 137 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSPT1 | G1 to S phase transition 1 |
| GTPBP1 | GTP binding protein 1 |
| HDAC11 | histone deacetylase 11 |
| HDAC6 | histone deacetylase 6 |
| HFE | hemochromatosis |
| HPN | hepsin |
| HRG | histidine-rich glycoprotein |
| HSF1 | heat shock transcription factor 1 |
| IL32 | interleukin 32 |
| JAK3 | Janus kinase 3 |
| KIAA1109 | KIAA1109 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KITLG | KIT ligand |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LMAN1 | lectin, mannose-binding, 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MCL1 | myeloid cell leukemia 1 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MFN2 | mitofusin 2 |
| MTCP1 | mature T-cell proliferation 1 |
| MTMR1 | myotubularin related protein 1 |
| NEK9 | NIMA-related kinase 9 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PASK | PAS domain containing serine/threonine kinase |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PEX16 | peroxisomal biogenesis factor 16 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PLCL2 | phospholipase C-like 2 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PRKCA | protein kinase C, alpha |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| RAB35 | RAB35, member RAS oncogene family |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RARG | retinoic acid receptor, gamma |
| RND1 | Rho family GTPase 1 |
| RNF122 | ring finger protein 122 |
| RNF43 | ring finger protein 43 |
| RUNX1 | runt-related transcription factor 1 |
| SAPCD1 | suppressor APC domain containing 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SORT1 | sortilin 1 |
| SP1 | Sp1 transcription factor |
| SPPL2B | signal peptide peptidase like 2B |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRPR | signal recognition particle receptor (docking protein) |
| STC1 | stanniocalcin 1 |
| SYNJ1 | synaptojanin 1 |
| SYT2 | synaptotagmin II |
| TACR1 | tachykinin receptor 1 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TMEM206 | transmembrane protein 206 |
| TMEM259 | transmembrane protein 259 |
| TMOD1 | tropomodulin 1 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TONSL | tonsoku-like, DNA repair protein |
| TUBGCP2 | tubulin, gamma complex associated protein 2 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| WT1 | Wilms tumor 1 |
| ZNF44 | zinc finger protein 44 |
| Symbol | Name |
|---|---|
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ALPK1 | alpha-kinase 1 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BEST2 | bestrophin 2 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CAPN15 | calpain 15 |
| CCDC177 | coiled-coil domain containing 177 |
| CD53 | CD53 molecule |
| CENPO | centromere protein O |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLSPN | claspin |
| CRY2 | cryptochrome circadian clock 2 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CXORF21 | chromosome X open reading frame 21 |
| DBF4B | DBF4 zinc finger B |
| DNM3 | dynamin 3 |
| EFNB1 | ephrin-B1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERCC5 | excision repair cross-complementation group 5 |
| FGF23 | fibroblast growth factor 23 |
| FLT4 | fms-related tyrosine kinase 4 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLB1L | galactosidase, beta 1-like |
| GLRA1 | glycine receptor, alpha 1 |
| GPR85 | G protein-coupled receptor 85 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BM | histone cluster 1, H2bm |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXC11 | homeobox C11 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KCNJ12 | potassium channel, inwardly rectifying subfamily J, member 12 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLHL25 | kelch-like family member 25 |
| KRT32 | keratin 32, type I |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIMD2 | LIM domain containing 2 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LYRM9 | LYR motif containing 9 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PCDHA5 | protocadherin alpha 5 |
| PENK | proenkephalin |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| POLL | polymerase (DNA directed), lambda |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF39 | ring finger protein 39 |
| SCARA3 | scavenger receptor class A, member 3 |
| SLC10A2 | solute carrier family 10 (sodium/bile acid cotransporter), member 2 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYNGR4 | synaptogyrin 4 |
| TEP1 | telomerase-associated protein 1 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM159 | transmembrane protein 159 |
| TMEM19 | transmembrane protein 19 |
| TMEM8B | transmembrane protein 8B |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TRIM16 | tripartite motif containing 16 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TSPAN32 | tetraspanin 32 |
| TUBA4B | tubulin, alpha 4b |
| UNKL | unkempt family zinc finger-like |
| VEZT | vezatin, adherens junctions transmembrane protein |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF160 | zinc finger protein 160 |
| ZNF219 | zinc finger protein 219 |
| ZNF264 | zinc finger protein 264 |
| ZNF280B | zinc finger protein 280B |
| ZNF652 | zinc finger protein 652 |
| ZNF749 | zinc finger protein 749 |
