flucloxacillin-3128 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the flucloxacillin-3128 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ACTA1 actin, alpha 1, skeletal muscle
ADA adenosine deaminase
ADORA1 adenosine A1 receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANGPTL2 angiopoietin-like 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKH ANKH inorganic pyrophosphate transport regulator
BEGAIN brain-enriched guanylate kinase-associated
BTBD7 BTB (POZ) domain containing 7
BTF3P11 basic transcription factor 3 pseudogene 11
CAPN3 calpain 3, (p94)
CCDC57 coiled-coil domain containing 57
CDA cytidine deaminase
CELA2A chymotrypsin-like elastase family, member 2A
CENPT centromere protein T
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COPE coatomer protein complex, subunit epsilon
CST4 cystatin S
CYHR1 cysteine/histidine-rich 1
DEPTOR DEP domain containing MTOR-interacting protein
DSP desmoplakin
DTNA dystrobrevin, alpha
EEA1 early endosome antigen 1
EPHB4 EPH receptor B4
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
FABP3 fatty acid binding protein 3, muscle and heart
FAM46C family with sequence similarity 46, member C
FBXL7 F-box and leucine-rich repeat protein 7
FGFR1 fibroblast growth factor receptor 1
FJX1 four jointed box 1 (Drosophila)
FLRT2 fibronectin leucine rich transmembrane protein 2
FLT1 fms-related tyrosine kinase 1
FSD1 fibronectin type III and SPRY domain containing 1
GSG1 germ cell associated 1
GSPT1 G1 to S phase transition 1
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HFE hemochromatosis
IFITM1 interferon induced transmembrane protein 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL17RC interleukin 17 receptor C
IL1A interleukin 1, alpha
KAT8 K(lysine) acetyltransferase 8
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCTD13 potassium channel tetramerization domain containing 13
KIAA0319L KIAA0319-like
KIDINS220 kinase D-interacting substrate, 220kDa
KLF3 Kruppel-like factor 3 (basic)
KRT18 keratin 18, type I
LECT1 leukocyte cell derived chemotaxin 1
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
MYOF myoferlin
NCS1 neuronal calcium sensor 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
OSBPL1A oxysterol binding protein-like 1A
PADI2 peptidyl arginine deiminase, type II
PAPPA2 pappalysin 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PBX2 pre-B-cell leukemia homeobox 2
PCBP4 poly(rC) binding protein 4
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLEK2 pleckstrin 2
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
POMZP3 POM121 and ZP3 fusion
PSG11 pregnancy specific beta-1-glycoprotein 11
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF25 ring finger protein 25
SAFB scaffold attachment factor B
SBF1 SET binding factor 1
SELPLG selectin P ligand
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIPA1 signal-induced proliferation-associated 1
SIX3 SIX homeobox 3
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TGFB1 transforming growth factor, beta 1
TICAM1 toll-like receptor adaptor molecule 1
TM4SF20 transmembrane 4 L six family member 20
TP53TG1 TP53 target 1 (non-protein coding)
TSC22D2 TSC22 domain family, member 2
WIZ widely interspaced zinc finger motifs
WWC1 WW and C2 domain containing 1
ZNF428 zinc finger protein 428
ZNF473 zinc finger protein 473
ZNF518A zinc finger protein 518A
ZNF696 zinc finger protein 696
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN31 zinc finger and SCAN domain containing 31

decreased expression

Symbol Name
AEN apoptosis enhancing nuclease
BAMBI BMP and activin membrane-bound inhibitor
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF169 chromosome 14 open reading frame 169
C5ORF45 chromosome 5 open reading frame 45
C7ORF43 chromosome 7 open reading frame 43
CCDC9 coiled-coil domain containing 9
CD34 CD34 molecule
CD70 CD70 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDHR2 cadherin-related family member 2
CDR2L cerebellar degeneration-related protein 2-like
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CLEC3B C-type lectin domain family 3, member B
CLIP2 CAP-GLY domain containing linker protein 2
CNTLN centlein, centrosomal protein
CORT cortistatin
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DDN dendrin
DGAT1 diacylglycerol O-acyltransferase 1
DSCAM Down syndrome cell adhesion molecule
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
ERN2 endoplasmic reticulum to nucleus signaling 2
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF22 fibroblast growth factor 22
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXC1 forkhead box C1
FOXO4 forkhead box O4
FRS3 fibroblast growth factor receptor substrate 3
GPR35 G protein-coupled receptor 35
GRPR gastrin-releasing peptide receptor
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HIST1H4D histone cluster 1, H4d
IFI6 interferon, alpha-inducible protein 6
IL2 interleukin 2
IL3RA interleukin 3 receptor, alpha (low affinity)
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INO80D INO80 complex subunit D
IQSEC2 IQ motif and Sec7 domain 2
KLHL28 kelch-like family member 28
LEFTY1 left-right determination factor 1
LINC00216 long intergenic non-protein coding RNA 216
LOC100286895 cell division cycle 27 homolog pseudogene
LOC100287590 uncharacterized LOC100287590
LSP1 lymphocyte-specific protein 1
MAGEH1 melanoma antigen family H1
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MEFV Mediterranean fever
MRPL44 mitochondrial ribosomal protein L44
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVP major vault protein
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NDE1 nudE neurodevelopment protein 1
NKX3-2 NK3 homeobox 2
NOD2 nucleotide-binding oligomerization domain containing 2
NTSR1 neurotensin receptor 1 (high affinity)
NXPH4 neurexophilin 4
PLAT plasminogen activator, tissue
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POM121L2 POM121 transmembrane nucleoporin-like 2
POMT1 protein-O-mannosyltransferase 1
POR P450 (cytochrome) oxidoreductase
POU5F1B POU class 5 homeobox 1B
PPT2 palmitoyl-protein thioesterase 2
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RAP1GAP2 RAP1 GTPase activating protein 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCAI suppressor of cancer cell invasion
SETBP1 SET binding protein 1
SETD1A SET domain containing 1A
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SPHK1 sphingosine kinase 1
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
ST5 suppression of tumorigenicity 5
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAS2R1 taste receptor, type 2, member 1
TBC1D19 TBC1 domain family, member 19
TCTN2 tectonic family member 2
TGFB3 transforming growth factor, beta 3
TIGD6 tigger transposable element derived 6
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TONSL tonsoku-like, DNA repair protein
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VEGFC vascular endothelial growth factor C
VPS9D1 VPS9 domain containing 1
ZFHX4 zinc finger homeobox 4
ZNF324 zinc finger protein 324
ZNF492 zinc finger protein 492
ZNF76 zinc finger protein 76
ZNF778 zinc finger protein 778
ZNF816 zinc finger protein 816