flucloxacillin-6507 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the flucloxacillin-6507 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ADGRL3 adhesion G protein-coupled receptor L3
AGRP agouti related neuropeptide
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALDOB aldolase B, fructose-bisphosphate
ALS2CL ALS2 C-terminal like
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
AQP3 aquaporin 3 (Gill blood group)
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
B9D1 B9 protein domain 1
BCAM basal cell adhesion molecule (Lutheran blood group)
BEX1 brain expressed, X-linked 1
BTF3P11 basic transcription factor 3 pseudogene 11
C17ORF53 chromosome 17 open reading frame 53
C21ORF2 chromosome 21 open reading frame 2
CA4 carbonic anhydrase IV
CABP1 calcium binding protein 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPN9 calpain 9
CCRL2 chemokine (C-C motif) receptor-like 2
CD101 CD101 molecule
CD34 CD34 molecule
CRIP1 cysteine-rich protein 1 (intestinal)
CTSE cathepsin E
DCTN2 dynactin 2 (p50)
DESI2 desumoylating isopeptidase 2
DGAT1 diacylglycerol O-acyltransferase 1
DLC1 DLC1 Rho GTPase activating protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DTNA dystrobrevin, alpha
EPHA1 EPH receptor A1
FAM134B family with sequence similarity 134, member B
FGD1 FYVE, RhoGEF and PH domain containing 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GEM GTP binding protein overexpressed in skeletal muscle
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPER1 G protein-coupled estrogen receptor 1
HOXC4 homeobox C4
IL2RB interleukin 2 receptor, beta
JAM3 junctional adhesion molecule 3
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KLHL29 kelch-like family member 29
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MNMIP1 manchette microtubule inner protein 1
MOCS1 molybdenum cofactor synthesis 1
MST1 macrophage stimulating 1
MVK mevalonate kinase
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NBL1 neuroblastoma 1, DAN family BMP antagonist
NID1 nidogen 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOX1 NADPH oxidase 1
NPVF neuropeptide VF precursor
NSUN6 NOP2/Sun domain family, member 6
OR10H1 olfactory receptor, family 10, subfamily H, member 1
PLA2G1B phospholipase A2, group IB (pancreas)
PLAUR plasminogen activator, urokinase receptor
PLK3 polo-like kinase 3
POU3F2 POU class 3 homeobox 2
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP4R4 protein phosphatase 4, regulatory subunit 4
PPP5C protein phosphatase 5, catalytic subunit
PRB1 proline-rich protein BstNI subfamily 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RCAN1 regulator of calcineurin 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFPL1 ret finger protein-like 1
RGS3 regulator of G-protein signaling 3
RIN1 Ras and Rab interactor 1
RTN2 reticulon 2
SBF1 SET binding factor 1
SC5D sterol-C5-desaturase
SCARB1 scavenger receptor class B, member 1
SKAP1 src kinase associated phosphoprotein 1
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TENM1 teneurin transmembrane protein 1
TLDC1 TBC/LysM-associated domain containing 1
TLN1 talin 1
TNS1 tensin 1
USP2 ubiquitin specific peptidase 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZBTB48 zinc finger and BTB domain containing 48

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACAD10 acyl-CoA dehydrogenase family, member 10
ADCY6 adenylate cyclase 6
AMH anti-Mullerian hormone
ARHGAP24 Rho GTPase activating protein 24
ARR3 arrestin 3, retinal (X-arrestin)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BIRC7 baculoviral IAP repeat containing 7
C8ORF60 chromosome 8 open reading frame 60
CBX7 chromobox homolog 7
CCDC25 coiled-coil domain containing 25
CCNJ cyclin J
CCP110 centriolar coiled coil protein 110kDa
CDKL3 cyclin-dependent kinase-like 3
CLCN2 chloride channel, voltage-sensitive 2
CLCN5 chloride channel, voltage-sensitive 5
CORT cortistatin
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPOX coproporphyrinogen oxidase
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
F3 coagulation factor III (thromboplastin, tissue factor)
FBRS fibrosin
FKBP14 FK506 binding protein 14, 22 kDa
FRK fyn-related Src family tyrosine kinase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR3 G protein-coupled receptor 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTT1 glutathione S-transferase theta 1
GUSBP3 glucuronidase, beta pseudogene 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXB2 homeobox B2
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IDI2-AS1 IDI2 antisense RNA 1
INF2 inverted formin, FH2 and WH2 domain containing
IRAK4 interleukin-1 receptor-associated kinase 4
JMJD4 jumonji domain containing 4
KCNK12 potassium channel, two pore domain subfamily K, member 12
KDM5C lysine (K)-specific demethylase 5C
KIF13B kinesin family member 13B
KIF18A kinesin family member 18A
KLHL25 kelch-like family member 25
KREMEN2 kringle containing transmembrane protein 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMO2 LIM domain only 2 (rhombotin-like 1)
LRP3 low density lipoprotein receptor-related protein 3
MAGEF1 melanoma antigen family F1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MOCS3 molybdenum cofactor synthesis 3
MRPS18C mitochondrial ribosomal protein S18C
MT1HL1 metallothionein 1H-like 1
MUC3A mucin 3A, cell surface associated
MUC3B mucin 3B, cell surface associated
NECAP2 NECAP endocytosis associated 2
NFE2L3 nuclear factor, erythroid 2-like 3
NHEJ1 nonhomologous end-joining factor 1
NIPAL2 NIPA-like domain containing 2
NLK nemo-like kinase
NLRX1 NLR family member X1
NOL12 nucleolar protein 12
PAIP2B poly(A) binding protein interacting protein 2B
PCDHB3 protocadherin beta 3
PDGFD platelet derived growth factor D
PHACTR4 phosphatase and actin regulator 4
PODXL2 podocalyxin-like 2
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS53 protease, serine, 53
RAB23 RAB23, member RAS oncogene family
RECQL4 RecQ protein-like 4
RHBG Rh family, B glycoprotein (gene/pseudogene)
RLN1 relaxin 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPGR retinitis pigmentosa GTPase regulator
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SGPP1 sphingosine-1-phosphate phosphatase 1
SKI SKI proto-oncogene
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPINK4 serine peptidase inhibitor, Kazal type 4
SRD5A3 steroid 5 alpha-reductase 3
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBX19 T-box 19
TET3 tet methylcytosine dioxygenase 3
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TPCN1 two pore segment channel 1
TRAPPC13 trafficking protein particle complex 13
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF573 zinc finger protein 573