flucytosine-3073 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the flucytosine-3073 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AGFG2 ArfGAP with FG repeats 2
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
APOC4 apolipoprotein C-IV
ARRB1 arrestin, beta 1
ATP10A ATPase, class V, type 10A
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP7B ATPase, Cu++ transporting, beta polypeptide
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BMP1 bone morphogenetic protein 1
C17ORF53 chromosome 17 open reading frame 53
C1ORF68 chromosome 1 open reading frame 68
C21ORF2 chromosome 21 open reading frame 2
CARD14 caspase recruitment domain family, member 14
CCDC170 coiled-coil domain containing 170
CD300A CD300a molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COBLL1 cordon-bleu WH2 repeat protein-like 1
CPTP ceramide-1-phosphate transfer protein
CXXC4 CXXC finger protein 4
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DMP1 dentin matrix acidic phosphoprotein 1
DNAH17 dynein, axonemal, heavy chain 17
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNPEP aspartyl aminopeptidase
DOK5 docking protein 5
DPEP2 dipeptidase 2
DSCAM Down syndrome cell adhesion molecule
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGR4 early growth response 4
EML3 echinoderm microtubule associated protein like 3
ERN1 endoplasmic reticulum to nucleus signaling 1
ETV1 ets variant 1
FAM65B family with sequence similarity 65, member B
FBP1 fructose-1,6-bisphosphatase 1
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FJX1 four jointed box 1 (Drosophila)
FXYD3 FXYD domain containing ion transport regulator 3
GDF10 growth differentiation factor 10
GLRA1 glycine receptor, alpha 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPC4 glypican 4
GRIP2 glutamate receptor interacting protein 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
ICOSLG inducible T-cell co-stimulator ligand
INO80B INO80 complex subunit B
INVS inversin
JAG2 jagged 2
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
LAMC3 laminin, gamma 3
LRP5 low density lipoprotein receptor-related protein 5
LTBP1 latent transforming growth factor beta binding protein 1
MAP4 microtubule-associated protein 4
MAX MYC associated factor X
MLH3 mutL homolog 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC1 mucin 1, cell surface associated
MXD4 MAX dimerization protein 4
MYL10 myosin, light chain 10, regulatory
MYT1 myelin transcription factor 1
NRCAM neuronal cell adhesion molecule
PCDH9 protocadherin 9
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G2E phospholipase A2, group IIE
PLEC plectin
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PSEN2 presenilin 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAD21L1 RAD21-like 1 (S. pombe)
SAG S-antigen; retina and pineal gland (arrestin)
SCLY selenocysteine lyase
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SFTPA2 surfactant protein A2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SORBS3 sorbin and SH3 domain containing 3
SPATA2L spermatogenesis associated 2-like
SPHK2 sphingosine kinase 2
SSPN sarcospan
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SYN3 synapsin III
TRBC1 T cell receptor beta constant 1
TREML2 triggering receptor expressed on myeloid cells-like 2
TRIM3 tripartite motif containing 3
TTLL3 tubulin tyrosine ligase-like family member 3
VASH2 vasohibin 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF185 zinc finger protein 185 (LIM domain)
ZNF444 zinc finger protein 444
ZNF518A zinc finger protein 518A
ZNF609 zinc finger protein 609
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
AMIGO2 adhesion molecule with Ig-like domain 2
ARL15 ADP-ribosylation factor-like 15
ARMC7 armadillo repeat containing 7
ASPN asporin
BEND5 BEN domain containing 5
BTF3P12 basic transcription factor 3 pseudogene 12
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C16ORF59 chromosome 16 open reading frame 59
C1QTNF3 C1q and tumor necrosis factor related protein 3
C7ORF43 chromosome 7 open reading frame 43
CCDC9 coiled-coil domain containing 9
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDADC1 cytidine and dCMP deaminase domain containing 1
CEP72 centrosomal protein 72kDa
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CNTLN centlein, centrosomal protein
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DENND5B DENN/MADD domain containing 5B
DEPDC1 DEP domain containing 1
EXOC6B exocyst complex component 6B
FAM127B family with sequence similarity 127, member B
FAM53B family with sequence similarity 53, member B
FGL1 fibrinogen-like 1
FKBP9 FK506 binding protein 9, 63 kDa
FOXO4 forkhead box O4
FRS2 fibroblast growth factor receptor substrate 2
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GCH1 GTP cyclohydrolase 1
GDAP1 ganglioside induced differentiation associated protein 1
GID4 GID complex subunit 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPR132 G protein-coupled receptor 132
HIST1H1B histone cluster 1, H1b
HIST1H4D histone cluster 1, H4d
HIST1H4E histone cluster 1, H4e
HLA-DMA major histocompatibility complex, class II, DM alpha
ICK intestinal cell (MAK-like) kinase
IDI2-AS1 IDI2 antisense RNA 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGLV1-44 immunoglobulin lambda variable 1-44
IL11RA interleukin 11 receptor, alpha
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IPP intracisternal A particle-promoted polypeptide
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KLF1 Kruppel-like factor 1 (erythroid)
KLF3 Kruppel-like factor 3 (basic)
KLHL28 kelch-like family member 28
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LIMD2 LIM domain containing 2
LOC390998 ribosomal protein L10 pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTC4S leukotriene C4 synthase
LY6E lymphocyte antigen 6 complex, locus E
MB myoglobin
MFSD6 major facilitator superfamily domain containing 6
MKRN3 makorin ring finger protein 3
MVD mevalonate (diphospho) decarboxylase
MX2 MX dynamin-like GTPase 2
MXD3 MAX dimerization protein 3
MYO5C myosin VC
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NECAB3 N-terminal EF-hand calcium binding protein 3
NINJ2 ninjurin 2
NOD2 nucleotide-binding oligomerization domain containing 2
NPFFR1 neuropeptide FF receptor 1
PAQR4 progestin and adipoQ receptor family member IV
PDGFD platelet derived growth factor D
PDGFRL platelet-derived growth factor receptor-like
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLTP phospholipid transfer protein
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRKCZ protein kinase C, zeta
PSG4 pregnancy specific beta-1-glycoprotein 4
PTTG3P pituitary tumor-transforming 3, pseudogene
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF141 ring finger protein 141
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMA4 glucuronidase, beta pseudogene
STAP1 signal transducing adaptor family member 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
THAP10 THAP domain containing 10
TMEM180 transmembrane protein 180
TMEM62 transmembrane protein 62
ULBP2 UL16 binding protein 2
USB1 U6 snRNA biogenesis 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR33 WD repeat domain 33
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF345 zinc finger protein 345
ZNF350 zinc finger protein 350
ZNF552 zinc finger protein 552
ZNF701 zinc finger protein 701
ZNHIT2 zinc finger, HIT-type containing 2