flucytosine-5289 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the flucytosine-5289 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ADM adrenomedullin
ALCAM activated leukocyte cell adhesion molecule
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALS2CL ALS2 C-terminal like
ARMC4 armadillo repeat containing 4
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASB1 ankyrin repeat and SOCS box containing 1
ATRX alpha thalassemia/mental retardation syndrome X-linked
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BMP8B bone morphogenetic protein 8b
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C14ORF93 chromosome 14 open reading frame 93
C17ORF53 chromosome 17 open reading frame 53
C17ORF70 chromosome 17 open reading frame 70
C22ORF46 chromosome 22 open reading frame 46
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCDC9 coiled-coil domain containing 9
CD82 CD82 molecule
CENPO centromere protein O
CEP68 centrosomal protein 68kDa
CIDEB cell death-inducing DFFA-like effector b
COMMD4 COMM domain containing 4
CPTP ceramide-1-phosphate transfer protein
CUL9 cullin 9
CYLD cylindromatosis (turban tumor syndrome)
DNAH17 dynein, axonemal, heavy chain 17
DSCR3 Down syndrome critical region 3
EGFR epidermal growth factor receptor
EGR1 early growth response 1
F3 coagulation factor III (thromboplastin, tissue factor)
FADS3 fatty acid desaturase 3
FAM149B1 family with sequence similarity 149, member B1
FCHO1 FCH domain only 1
FEM1B fem-1 homolog b (C. elegans)
FKBP1B FK506 binding protein 1B, 12.6 kDa
FKBP8 FK506 binding protein 8, 38kDa
FOXO1 forkhead box O1
GPRC5B G protein-coupled receptor, class C, group 5, member B
HDLBP high density lipoprotein binding protein
HFE hemochromatosis
HLA-G major histocompatibility complex, class I, G
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB5 integrin, beta 5
ITSN1 intersectin 1 (SH3 domain protein)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KAT6B K(lysine) acetyltransferase 6B
KIAA1324 KIAA1324
KLHL20 kelch-like family member 20
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LONP2 lon peptidase 2, peroxisomal
LPIN1 lipin 1
LTK leukocyte receptor tyrosine kinase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCAM melanoma cell adhesion molecule
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MTA1 metastasis associated 1
MXD3 MAX dimerization protein 3
NDRG4 NDRG family member 4
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NTF3 neurotrophin 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PDGFA platelet-derived growth factor alpha polypeptide
PDLIM5 PDZ and LIM domain 5
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RBBP9 retinoblastoma binding protein 9
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RER1 retention in endoplasmic reticulum sorting receptor 1
RPL10 ribosomal protein L10
RYR2 ryanodine receptor 2 (cardiac)
S100A4 S100 calcium binding protein A4
S100A9 S100 calcium binding protein A9
SGSM3 small G protein signaling modulator 3
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SPATA5L1 spermatogenesis associated 5-like 1
TM6SF1 transmembrane 6 superfamily member 1
TMEM53 transmembrane protein 53
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIM25 tripartite motif containing 25
TSC22D2 TSC22 domain family, member 2
TTLL3 tubulin tyrosine ligase-like family member 3
VIPR1 vasoactive intestinal peptide receptor 1
WDR1 WD repeat domain 1
ZER1 zyg-11 related, cell cycle regulator
ZFP36L2 ZFP36 ring finger protein-like 2
ZMYND8 zinc finger, MYND-type containing 8
ZNF37BP zinc finger protein 37B, pseudogene
ZNF442 zinc finger protein 442

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACYP2 acylphosphatase 2, muscle type
ADAM15 ADAM metallopeptidase domain 15
ADCY6 adenylate cyclase 6
AEN apoptosis enhancing nuclease
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARL4A ADP-ribosylation factor-like 4A
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCORL1 BCL6 corepressor-like 1
BEX4 brain expressed, X-linked 4
C6ORF47 chromosome 6 open reading frame 47
CBX7 chromobox homolog 7
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CNPY3 canopy FGF signaling regulator 3
CORO2A coronin, actin binding protein, 2A
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
DHCR24 24-dehydrocholesterol reductase
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EGR3 early growth response 3
ERCC5 excision repair cross-complementation group 5
FCHSD2 FCH and double SH3 domains 2
GAR1 GAR1 ribonucleoprotein
GLB1L2 galactosidase, beta 1-like 2
GLI3 GLI family zinc finger 3
GMCL1 germ cell-less, spermatogenesis associated 1
GRAMD3 GRAM domain containing 3
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GTPBP3 GTP binding protein 3 (mitochondrial)
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
IGFLR1 IGF-like family receptor 1
IRF6 interferon regulatory factor 6
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIAA0895 KIAA0895
KIF18B kinesin family member 18B
LAMB2 laminin, beta 2 (laminin S)
LMNB1 lamin B1
LOC100287590 uncharacterized LOC100287590
LOC730101 uncharacterized LOC730101
LRRC42 leucine rich repeat containing 42
MED15 mediator complex subunit 15
METTL2B methyltransferase like 2B
MGA MGA, MAX dimerization protein
MINPP1 multiple inositol-polyphosphate phosphatase 1
MITF microphthalmia-associated transcription factor
MKNK2 MAP kinase interacting serine/threonine kinase 2
MPI mannose phosphate isomerase
MSX1 msh homeobox 1
MTCL1 microtubule crosslinking factor 1
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NDRG1 N-myc downstream regulated 1
NMU neuromedin U
NOTCH1 notch 1
NPM3 nucleophosmin/nucleoplasmin 3
NSD1 nuclear receptor binding SET domain protein 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PARPBP PARP1 binding protein
PCOLCE2 procollagen C-endopeptidase enhancer 2
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PHC2 polyhomeotic homolog 2 (Drosophila)
PPAN peter pan homolog (Drosophila)
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRICKLE3 prickle homolog 3 (Drosophila)
PROS1 protein S (alpha)
PSKH1 protein serine kinase H1
PTOV1 prostate tumor overexpressed 1
RABL3 RAB, member of RAS oncogene family-like 3
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RECQL4 RecQ protein-like 4
RNF121 ring finger protein 121
RPS14P3 ribosomal protein S14 pseudogene 3
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RWDD2A RWD domain containing 2A
SCIN scinderin
SGMS1 sphingomyelin synthase 1
SNX16 sorting nexin 16
STAG3 stromal antigen 3
STK16 serine/threonine kinase 16
TCERG1 transcription elongation regulator 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
UBXN8 UBX domain protein 8
USP6NL USP6 N-terminal like
VGF VGF nerve growth factor inducible
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WBP2 WW domain binding protein 2
WWC2 WW and C2 domain containing 2
ZBTB10 zinc finger and BTB domain containing 10
ZBTB3 zinc finger and BTB domain containing 3
ZNF276 zinc finger protein 276
ZNF573 zinc finger protein 573
ZNF7 zinc finger protein 7