| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the flucytosine-6450 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ADRB2 | adrenoceptor beta 2, surface |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ATP10B | ATPase, class V, type 10B |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C1ORF68 | chromosome 1 open reading frame 68 |
| CALB1 | calbindin 1, 28kDa |
| CCDC87 | coiled-coil domain containing 87 |
| CDK3 | cyclin-dependent kinase 3 |
| CLEC1A | C-type lectin domain family 1, member A |
| CLTC | clathrin, heavy chain (Hc) |
| CLUL1 | clusterin-like 1 (retinal) |
| CNN3 | calponin 3, acidic |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COL6A1 | collagen, type VI, alpha 1 |
| COMMD4 | COMM domain containing 4 |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CYP3A43 | cytochrome P450, family 3, subfamily A, polypeptide 43 |
| DENND5B | DENN/MADD domain containing 5B |
| DFNB31 | deafness, autosomal recessive 31 |
| DIO2 | deiodinase, iodothyronine, type II |
| DOCK6 | dedicator of cytokinesis 6 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP7 | dual specificity phosphatase 7 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| FGF13 | fibroblast growth factor 13 |
| FGF20 | fibroblast growth factor 20 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GAL | galanin/GMAP prepropeptide |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GGTLC1 | gamma-glutamyltransferase light chain 1 |
| GLUL | glutamate-ammonia ligase |
| GPR68 | G protein-coupled receptor 68 |
| GRM7 | glutamate receptor, metabotropic 7 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HGFAC | HGF activator |
| HIST1H2BN | histone cluster 1, H2bn |
| HOXA2 | homeobox A2 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| KRT17 | keratin 17, type I |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LMF2 | lipase maturation factor 2 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRC23 | leucine rich repeat containing 23 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| NUP54 | nucleoporin 54kDa |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAB6A | RAB6A, member RAS oncogene family |
| RAB6B | RAB6B, member RAS oncogene family |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RBM17 | RNA binding motif protein 17 |
| RNF185 | ring finger protein 185 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SDC3 | syndecan 3 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SSTR4 | somatostatin receptor 4 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| SUGP1 | SURP and G patch domain containing 1 |
| SVIL | supervillin |
| SYNJ2 | synaptojanin 2 |
| TBC1D19 | TBC1 domain family, member 19 |
| TEX14 | testis expressed 14 |
| TEX261 | testis expressed 261 |
| TRIM21 | tripartite motif containing 21 |
| TSC22D2 | TSC22 domain family, member 2 |
| TUBA3C | tubulin, alpha 3c |
| USP46 | ubiquitin specific peptidase 46 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WIZ | widely interspaced zinc finger motifs |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF227 | zinc finger protein 227 |
| ZNF473 | zinc finger protein 473 |
| ZNF532 | zinc finger protein 532 |
| ZNF750 | zinc finger protein 750 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAM2 | ADAM metallopeptidase domain 2 |
| AMH | anti-Mullerian hormone |
| ANO10 | anoctamin 10 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BMP15 | bone morphogenetic protein 15 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CBX7 | chromobox homolog 7 |
| CBY1 | chibby homolog 1 (Drosophila) |
| CCDC9 | coiled-coil domain containing 9 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CGA | glycoprotein hormones, alpha polypeptide |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DMTN | dematin actin binding protein |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DOCK4 | dedicator of cytokinesis 4 |
| DYSF | dysferlin |
| ELMO3 | engulfment and cell motility 3 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ERCC6 | excision repair cross-complementation group 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXOC5 | exocyst complex component 5 |
| FBXO2 | F-box protein 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GRPR | gastrin-releasing peptide receptor |
| HOXB2 | homeobox B2 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| JMJD4 | jumonji domain containing 4 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL21 | kelch-like family member 21 |
| KLHL26 | kelch-like family member 26 |
| KRT13 | keratin 13, type I |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOXL3 | lysyl oxidase-like 3 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LRRC61 | leucine rich repeat containing 61 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MBTD1 | mbt domain containing 1 |
| MCC | mutated in colorectal cancers |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| N4BP3 | NEDD4 binding protein 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NECAP2 | NECAP endocytosis associated 2 |
| NPTX1 | neuronal pentraxin I |
| OLFML2A | olfactomedin-like 2A |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLD2 | phospholipase D2 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLXNA3 | plexin A3 |
| PRDM14 | PR domain containing 14 |
| PROL1 | proline rich, lacrimal 1 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS50 | protease, serine, 50 |
| QPCT | glutaminyl-peptide cyclotransferase |
| RANGRF | RAN guanine nucleotide release factor |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF170 | ring finger protein 170 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SRPX | sushi-repeat containing protein, X-linked |
| TDRD1 | tudor domain containing 1 |
| TMC7 | transmembrane channel-like 7 |
| TMEM121 | transmembrane protein 121 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM19 | transmembrane protein 19 |
| TNS2 | tensin 2 |
| TRAIP | TRAF interacting protein |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| VEGFB | vascular endothelial growth factor B |
| VGF | VGF nerve growth factor inducible |
| WDR25 | WD repeat domain 25 |
| ZNF16 | zinc finger protein 16 |
| ZNF35 | zinc finger protein 35 |
| ZNF665 | zinc finger protein 665 |