flucytosine-6450 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the flucytosine-6450 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADRB2 adrenoceptor beta 2, surface
AKAP8L A kinase (PRKA) anchor protein 8-like
ATP10B ATPase, class V, type 10B
BTF3P11 basic transcription factor 3 pseudogene 11
C1ORF68 chromosome 1 open reading frame 68
CALB1 calbindin 1, 28kDa
CCDC87 coiled-coil domain containing 87
CDK3 cyclin-dependent kinase 3
CLEC1A C-type lectin domain family 1, member A
CLTC clathrin, heavy chain (Hc)
CLUL1 clusterin-like 1 (retinal)
CNN3 calponin 3, acidic
CNOT4 CCR4-NOT transcription complex, subunit 4
COL6A1 collagen, type VI, alpha 1
COMMD4 COMM domain containing 4
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DENND5B DENN/MADD domain containing 5B
DFNB31 deafness, autosomal recessive 31
DIO2 deiodinase, iodothyronine, type II
DOCK6 dedicator of cytokinesis 6
DUSP1 dual specificity phosphatase 1
DUSP7 dual specificity phosphatase 7
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EIF3F eukaryotic translation initiation factor 3, subunit F
ELOVL2 ELOVL fatty acid elongase 2
FGF13 fibroblast growth factor 13
FGF20 fibroblast growth factor 20
FRMPD1 FERM and PDZ domain containing 1
GAL galanin/GMAP prepropeptide
GBP2 guanylate binding protein 2, interferon-inducible
GGTLC1 gamma-glutamyltransferase light chain 1
GLUL glutamate-ammonia ligase
GPR68 G protein-coupled receptor 68
GRM7 glutamate receptor, metabotropic 7
GSTTP1 glutathione S-transferase theta pseudogene 1
HCRP1 hepatocellular carcinoma-related HCRP1
HGFAC HGF activator
HIST1H2BN histone cluster 1, H2bn
HOXA2 homeobox A2
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KRT17 keratin 17, type I
LEF1 lymphoid enhancer-binding factor 1
LMF2 lipase maturation factor 2
LRP2 low density lipoprotein receptor-related protein 2
LRRC23 leucine rich repeat containing 23
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAP2K2 mitogen-activated protein kinase kinase 2
MIER2 mesoderm induction early response 1, family member 2
NOD2 nucleotide-binding oligomerization domain containing 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUP54 nucleoporin 54kDa
OPCML opioid binding protein/cell adhesion molecule-like
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB6A RAB6A, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM17 RNA binding motif protein 17
RNF185 ring finger protein 185
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SCAPER S-phase cyclin A-associated protein in the ER
SDC3 syndecan 3
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SETD8 SET domain containing (lysine methyltransferase) 8
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SSTR4 somatostatin receptor 4
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SUGP1 SURP and G patch domain containing 1
SVIL supervillin
SYNJ2 synaptojanin 2
TBC1D19 TBC1 domain family, member 19
TEX14 testis expressed 14
TEX261 testis expressed 261
TRIM21 tripartite motif containing 21
TSC22D2 TSC22 domain family, member 2
TUBA3C tubulin, alpha 3c
USP46 ubiquitin specific peptidase 46
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WIZ widely interspaced zinc finger motifs
ZBTB18 zinc finger and BTB domain containing 18
ZBTB48 zinc finger and BTB domain containing 48
ZHX3 zinc fingers and homeoboxes 3
ZNF227 zinc finger protein 227
ZNF473 zinc finger protein 473
ZNF532 zinc finger protein 532
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADAM15 ADAM metallopeptidase domain 15
ADAM2 ADAM metallopeptidase domain 2
AMH anti-Mullerian hormone
ANO10 anoctamin 10
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BMP15 bone morphogenetic protein 15
C10ORF95 chromosome 10 open reading frame 95
C7ORF43 chromosome 7 open reading frame 43
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBX7 chromobox homolog 7
CBY1 chibby homolog 1 (Drosophila)
CCDC9 coiled-coil domain containing 9
CD3D CD3d molecule, delta (CD3-TCR complex)
CGA glycoprotein hormones, alpha polypeptide
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOCK4 dedicator of cytokinesis 4
DYSF dysferlin
ELMO3 engulfment and cell motility 3
ELP3 elongator acetyltransferase complex subunit 3
ERCC6 excision repair cross-complementation group 6
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC5 exocyst complex component 5
FBXO2 F-box protein 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GMEB1 glucocorticoid modulatory element binding protein 1
GRPR gastrin-releasing peptide receptor
HOXB2 homeobox B2
HP1BP3 heterochromatin protein 1, binding protein 3
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IDI2-AS1 IDI2 antisense RNA 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
INF2 inverted formin, FH2 and WH2 domain containing
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JMJD4 jumonji domain containing 4
KCNK12 potassium channel, two pore domain subfamily K, member 12
KDM8 lysine (K)-specific demethylase 8
KLHL21 kelch-like family member 21
KLHL26 kelch-like family member 26
KRT13 keratin 13, type I
LAMP3 lysosomal-associated membrane protein 3
LIME1 Lck interacting transmembrane adaptor 1
LOXL3 lysyl oxidase-like 3
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC61 leucine rich repeat containing 61
LYPD1 LY6/PLAUR domain containing 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MBNL3 muscleblind-like splicing regulator 3
MBTD1 mbt domain containing 1
MCC mutated in colorectal cancers
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
N4BP3 NEDD4 binding protein 3
NDE1 nudE neurodevelopment protein 1
NECAP2 NECAP endocytosis associated 2
NPTX1 neuronal pentraxin I
OLFML2A olfactomedin-like 2A
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAIP2B poly(A) binding protein interacting protein 2B
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLXNA3 plexin A3
PRDM14 PR domain containing 14
PROL1 proline rich, lacrimal 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS50 protease, serine, 50
QPCT glutaminyl-peptide cyclotransferase
RANGRF RAN guanine nucleotide release factor
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF170 ring finger protein 170
RPL23AP32 ribosomal protein L23a pseudogene 32
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLMO1 slowmo homolog 1 (Drosophila)
SRPX sushi-repeat containing protein, X-linked
TDRD1 tudor domain containing 1
TMC7 transmembrane channel-like 7
TMEM121 transmembrane protein 121
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM19 transmembrane protein 19
TNS2 tensin 2
TRAIP TRAF interacting protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTLL1 tubulin tyrosine ligase-like family member 1
VEGFB vascular endothelial growth factor B
VGF VGF nerve growth factor inducible
WDR25 WD repeat domain 25
ZNF16 zinc finger protein 16
ZNF35 zinc finger protein 35
ZNF665 zinc finger protein 665