flucytosine-6690 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the flucytosine-6690 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACVR1B activin A receptor, type IB
ADGB androglobin
AIM2 absent in melanoma 2
APAF1 apoptotic peptidase activating factor 1
ARHGAP35 Rho GTPase activating protein 35
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ATXN2L ataxin 2-like
BAGE B melanoma antigen
BBC3 BCL2 binding component 3
BCR breakpoint cluster region
C5AR1 complement component 5a receptor 1
C5ORF42 chromosome 5 open reading frame 42
CASR calcium-sensing receptor
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC25C cell division cycle 25C
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CISH cytokine inducible SH2-containing protein
CLCN4 chloride channel, voltage-sensitive 4
CSF1R colony stimulating factor 1 receptor
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DAPK3 death-associated protein kinase 3
DNAH3 dynein, axonemal, heavy chain 3
DST dystonin
ESR2 estrogen receptor 2 (ER beta)
FAM13C family with sequence similarity 13, member C
FOSL2 FOS-like antigen 2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GP2 glycoprotein 2 (zymogen granule membrane)
GRM7 glutamate receptor, metabotropic 7
HIPK3 homeodomain interacting protein kinase 3
IDS iduronate 2-sulfatase
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL11 interleukin 11
IRX4 iroquois homeobox 4
IZUMO4 IZUMO family member 4
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KRT17 keratin 17, type I
KSR1 kinase suppressor of ras 1
KYNU kynureninase
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LIPG lipase, endothelial
LMOD1 leiomodin 1 (smooth muscle)
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAPK8 mitogen-activated protein kinase 8
MBNL2 muscleblind-like splicing regulator 2
MDM4 MDM4, p53 regulator
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MUC2 mucin 2, oligomeric mucus/gel-forming
NEUROD1 neuronal differentiation 1
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NPY neuropeptide Y
NRP2 neuropilin 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OTOF otoferlin
PBOV1 prostate and breast cancer overexpressed 1
PCDHA5 protocadherin alpha 5
PDE11A phosphodiesterase 11A
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDLIM5 PDZ and LIM domain 5
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKCA protein kinase C, alpha
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPH3AL rabphilin 3A-like (without C2 domains)
RPS3A ribosomal protein S3A
RUNX1 runt-related transcription factor 1
SCAPER S-phase cyclin A-associated protein in the ER
SEZ6L seizure related 6 homolog (mouse)-like
SFRP4 secreted frizzled-related protein 4
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMCP sperm mitochondria-associated cysteine-rich protein
SNTG1 syntrophin, gamma 1
SOS2 son of sevenless homolog 2 (Drosophila)
SPRR2B small proline-rich protein 2B
SSTR4 somatostatin receptor 4
TMOD1 tropomodulin 1
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM3 tripartite motif containing 3
TTC38 tetratricopeptide repeat domain 38
TUBA3C tubulin, alpha 3c
UPK1B uroplakin 1B
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VNN2 vanin 2
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGRG2 adhesion G protein-coupled receptor G2
AGMAT agmatine ureohydrolase (agmatinase)
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANP32A-IT1 ANP32A intronic transcript 1
APOLD1 apolipoprotein L domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
C14ORF93 chromosome 14 open reading frame 93
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CD68 CD68 molecule
CEL carboxyl ester lipase
CENPO centromere protein O
CFAP69 cilia and flagella associated protein 69
CHRDL1 chordin-like 1
DDN dendrin
E2F6 E2F transcription factor 6
FAM160B2 family with sequence similarity 160, member B2
FAM50B family with sequence similarity 50, member B
FBXL15 F-box and leucine-rich repeat protein 15
FKBP10 FK506 binding protein 10, 65 kDa
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLJ21369 uncharacterized protein FLJ21369
FOXC1 forkhead box C1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GRAMD1C GRAM domain containing 1C
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOOK1 hook microtubule-tethering protein 1
HOXA1 homeobox A1
HSPA1L heat shock 70kDa protein 1-like
IER3IP1 immediate early response 3 interacting protein 1
IFT140 intraflagellar transport 140
IL36RN interleukin 36 receptor antagonist
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIF13B kinesin family member 13B
KIRREL kin of IRRE like (Drosophila)
KPTN kaptin (actin binding protein)
KRT75 keratin 75, type II
LINC00341 long intergenic non-protein coding RNA 341
LRRC61 leucine rich repeat containing 61
METTL1 methyltransferase like 1
MGC12488
MRPL41 mitochondrial ribosomal protein L41
MRPL52 mitochondrial ribosomal protein L52
MTHFSD methenyltetrahydrofolate synthetase domain containing
MUC3A mucin 3A, cell surface associated
MUM1 melanoma associated antigen (mutated) 1
MYO1F myosin IF
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NRTN neurturin
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSR2 odd-skipped related transciption factor 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCDHGB5 protocadherin gamma subfamily B, 5
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLAG1 pleiomorphic adenoma gene 1
PLCD1 phospholipase C, delta 1
PODXL2 podocalyxin-like 2
POMT2 protein-O-mannosyltransferase 2
PRB3 proline-rich protein BstNI subfamily 3
PRR15L proline rich 15-like
PRSS53 protease, serine, 53
RABL6 RAB, member RAS oncogene family-like 6
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPL13P5 ribosomal protein L13 pseudogene 5
RUNX1-IT1 RUNX1 intronic transcript 1
SCARA3 scavenger receptor class A, member 3
SCG5 secretogranin V
SECISBP2 SECIS binding protein 2
SERINC5 serine incorporator 5
SGMS1 sphingomyelin synthase 1
SKI SKI proto-oncogene
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNX16 sorting nexin 16
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAOK1 TAO kinase 1
TMEM8B transmembrane protein 8B
TMSB15A thymosin beta 15a
TOM1 target of myb1 (chicken)
TTC30A tetratricopeptide repeat domain 30A
USP6 ubiquitin specific peptidase 6
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
WDR19 WD repeat domain 19
ZBTB24 zinc finger and BTB domain containing 24
ZNF177 zinc finger protein 177
ZNF197 zinc finger protein 197
ZNF205 zinc finger protein 205
ZNF37BP zinc finger protein 37B, pseudogene
ZNF668 zinc finger protein 668
ZNF770 zinc finger protein 770
ZSCAN2 zinc finger and SCAN domain containing 2