| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the flufenamic acid-2267 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ACACB | acetyl-CoA carboxylase beta |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) |
| AQP3 | aquaporin 3 (Gill blood group) |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATN1 | atrophin 1 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BDKRB2 | bradykinin receptor B2 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CALCR | calcitonin receptor |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CARD10 | caspase recruitment domain family, member 10 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CFAP70 | cilia and flagella associated protein 70 |
| CFHR2 | complement factor H-related 2 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CNTN5 | contactin 5 |
| COMT | catechol-O-methyltransferase |
| CT62 | cancer/testis antigen 62 |
| CTSO | cathepsin O |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DICER1 | dicer 1, ribonuclease type III |
| DOCK10 | dedicator of cytokinesis 10 |
| EFNB3 | ephrin-B3 |
| EHD2 | EH-domain containing 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGFR1 | fibroblast growth factor receptor 1 |
| GM2A | GM2 ganglioside activator |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPR137 | G protein-coupled receptor 137 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HFE | hemochromatosis |
| HIST1H3A | histone cluster 1, H3a |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IL17RC | interleukin 17 receptor C |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIF24 | kinesin family member 24 |
| KIF25 | kinesin family member 25 |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LYZL6 | lysozyme-like 6 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MED18 | mediator complex subunit 18 |
| MEF2C | myocyte enhancer factor 2C |
| MEF2D | myocyte enhancer factor 2D |
| METTL7A | methyltransferase like 7A |
| MID1 | midline 1 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NEK1 | NIMA-related kinase 1 |
| NF1 | neurofibromin 1 |
| NR1I2 | nuclear receptor subfamily 1, group I, member 2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NRL | neural retina leucine zipper |
| NUDCD3 | NudC domain containing 3 |
| ONECUT2 | one cut homeobox 2 |
| PDE10A | phosphodiesterase 10A |
| POFUT1 | protein O-fucosyltransferase 1 |
| POPDC3 | popeye domain containing 3 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRG3 | proteoglycan 3 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBM12B | RNA binding motif protein 12B |
| RBM17 | RNA binding motif protein 17 |
| RHEB | Ras homolog enriched in brain |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RND2 | Rho family GTPase 2 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RUNX1 | runt-related transcription factor 1 |
| S100A8 | S100 calcium binding protein A8 |
| SFTPB | surfactant protein B |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SNRK | SNF related kinase |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| SYNDIG1 | synapse differentiation inducing 1 |
| TBX5 | T-box 5 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM63A | transmembrane protein 63A |
| TPMT | thiopurine S-methyltransferase |
| TRPC6 | transient receptor potential cation channel, subfamily C, member 6 |
| TUBA3C | tubulin, alpha 3c |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABHD17B | abhydrolase domain containing 17B |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC121 | coiled-coil domain containing 121 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CLSPN | claspin |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ERCC6 | excision repair cross-complementation group 6 |
| ETNK2 | ethanolamine kinase 2 |
| F2R | coagulation factor II (thrombin) receptor |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM186A | family with sequence similarity 186, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOXI1 | forkhead box I1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPX2 | glutathione peroxidase 2 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BO | histone cluster 1, H2bo |
| HPN | hepsin |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KLHDC8A | kelch domain containing 8A |
| KRT24 | keratin 24, type I |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LIF | leukemia inhibitory factor |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MCC | mutated in colorectal cancers |
| MEFV | Mediterranean fever |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MT1H | metallothionein 1H |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRSN2 | neurensin 2 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PLA2G15 | phospholipase A2, group XV |
| PLCD1 | phospholipase C, delta 1 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RABL3 | RAB, member of RAS oncogene family-like 3 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RIN2 | Ras and Rab interactor 2 |
| S100A9 | S100 calcium binding protein A9 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SKI | SKI proto-oncogene |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNTA1 | syntrophin, alpha 1 |
| STMN3 | stathmin-like 3 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TBKBP1 | TBK1 binding protein 1 |
| TEAD3 | TEA domain family member 3 |
| TEX40 | testis expressed 40 |
| TFF2 | trefoil factor 2 |
| TLN1 | talin 1 |
| TMEM242 | transmembrane protein 242 |
| TMEM53 | transmembrane protein 53 |
| TOM1 | target of myb1 (chicken) |
| TPK1 | thiamin pyrophosphokinase 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VASH2 | vasohibin 2 |
| YY2 | YY2 transcription factor |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF10 | zinc finger protein 10 |
| ZNF428 | zinc finger protein 428 |
| ZNF442 | zinc finger protein 442 |
| ZNF747 | zinc finger protein 747 |
