| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the flumequine-1429 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABI2 | abl-interactor 2 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALPK1 | alpha-kinase 1 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa |
| BNIP1 | BCL2/adenovirus E1B 19kDa interacting protein 1 |
| BRAP | BRCA1 associated protein |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C2ORF68 | chromosome 2 open reading frame 68 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CARD14 | caspase recruitment domain family, member 14 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CCHCR1 | coiled-coil alpha-helical rod protein 1 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COG7 | component of oligomeric golgi complex 7 |
| COL10A1 | collagen, type X, alpha 1 |
| COX5B | cytochrome c oxidase subunit Vb |
| CREB3 | cAMP responsive element binding protein 3 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CYTH4 | cytohesin 4 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FKBPL | FK506 binding protein like |
| FSCN1 | fascin actin-bundling protein 1 |
| GCAT | glycine C-acetyltransferase |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GOLGA1 | golgin A1 |
| GPSM3 | G-protein signaling modulator 3 |
| GTF3C2 | general transcription factor IIIC, polypeptide 2, beta 110kDa |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| KIF14 | kinesin family member 14 |
| LBR | lamin B receptor |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP4 | microtubule-associated protein 4 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MED16 | mediator complex subunit 16 |
| MED18 | mediator complex subunit 18 |
| METTL13 | methyltransferase like 13 |
| NADK | NAD kinase |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NCOA3 | nuclear receptor coactivator 3 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NOTCH1 | notch 1 |
| NPAT | nuclear protein, ataxia-telangiectasia locus |
| OSBPL3 | oxysterol binding protein-like 3 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PML | promyelocytic leukemia |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PRMT7 | protein arginine methyltransferase 7 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB8B | RAB8B, member RAS oncogene family |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| REV1 | REV1, polymerase (DNA directed) |
| RHOC | ras homolog family member C |
| RHOH | ras homolog family member H |
| RSL1D1 | ribosomal L1 domain containing 1 |
| SEPW1 | selenoprotein W, 1 |
| SETD4 | SET domain containing 4 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC25A46 | solute carrier family 25, member 46 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SNX3 | sorting nexin 3 |
| SRRT | serrate, RNA effector molecule |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| TBC1D13 | TBC1 domain family, member 13 |
| TBC1D22A | TBC1 domain family, member 22A |
| THBS3 | thrombospondin 3 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TRA | T cell receptor alpha locus |
| TRABD | TraB domain containing |
| TRIM68 | tripartite motif containing 68 |
| TRIP10 | thyroid hormone receptor interactor 10 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| TUBB3 | tubulin, beta 3 class III |
| UBE4B | ubiquitination factor E4B |
| VARS | valyl-tRNA synthetase |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| WWC3 | WWC family member 3 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| ACOT9 | acyl-CoA thioesterase 9 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ANKRD46 | ankyrin repeat domain 46 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| CARD9 | caspase recruitment domain family, member 9 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CCDC90B | coiled-coil domain containing 90B |
| CCDC91 | coiled-coil domain containing 91 |
| CDC73 | cell division cycle 73 |
| CENPQ | centromere protein Q |
| CFL1 | cofilin 1 (non-muscle) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 |
| CPOX | coproporphyrinogen oxidase |
| CTH | cystathionine gamma-lyase |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component |
| DBF4 | DBF4 zinc finger |
| DCK | deoxycytidine kinase |
| DENND4A | DENN/MADD domain containing 4A |
| DMXL1 | Dmx-like 1 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 |
| DPYD | dihydropyrimidine dehydrogenase |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 |
| HMGB2 | high mobility group box 2 |
| IMPACT | impact RWD domain protein |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LACTB2 | lactamase, beta 2 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 |
| LYZ | lysozyme |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MAGT1 | magnesium transporter 1 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MGAM | maltase-glucoamylase |
| MLPH | melanophilin |
| MORC3 | MORC family CW-type zinc finger 3 |
| MRPL33 | mitochondrial ribosomal protein L33 |
| MTMR6 | myotubularin related protein 6 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| MYL12B | myosin, light chain 12B, regulatory |
| MYO9A | myosin IXA |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NAE1 | NEDD8 activating enzyme E1 subunit 1 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| NMI | N-myc (and STAT) interactor |
| NRIP1 | nuclear receptor interacting protein 1 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCNP | PEST proteolytic signal containing nuclear protein |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| RACGAP1 | Rac GTPase activating protein 1 |
| RANBP6 | RAN binding protein 6 |
| RBL1 | retinoblastoma-like 1 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RCOR1 | REST corepressor 1 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| RWDD3 | RWD domain containing 3 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC35F2 | solute carrier family 35, member F2 |
| STK39 | serine threonine kinase 39 |
| STXBP3 | syntaxin binding protein 3 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TBPL1 | TBP-like 1 |
| TFB2M | transcription factor B2, mitochondrial |
| THOC7 | THO complex 7 |
| TM9SF2 | transmembrane 9 superfamily member 2 |
| TMEM184C | transmembrane protein 184C |
| TMEM38B | transmembrane protein 38B |
| TRHDE | thyrotropin-releasing hormone degrading enzyme |
| TTF2 | transcription termination factor, RNA polymerase II |
| TTI1 | TELO2 interacting protein 1 |
| TUBA1A | tubulin, alpha 1a |
| TXNDC15 | thioredoxin domain containing 15 |
| USP6 | ubiquitin specific peptidase 6 |
| UTP11L | UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) |
| VRK2 | vaccinia related kinase 2 |
| XBP1 | X-box binding protein 1 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial |
| ZCCHC2 | zinc finger, CCHC domain containing 2 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZEB2 | zinc finger E-box binding homeobox 2 |
| ZNF217 | zinc finger protein 217 |
