| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the flumequine-2276 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ADRA1A | adrenoceptor alpha 1A |
| APOE | apolipoprotein E |
| AVPR1B | arginine vasopressin receptor 1B |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| C10ORF12 | chromosome 10 open reading frame 12 |
| CAV2 | caveolin 2 |
| CCDC181 | coiled-coil domain containing 181 |
| CD48 | CD48 molecule |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNTNAP2 | contactin associated protein-like 2 |
| COL11A1 | collagen, type XI, alpha 1 |
| COL3A1 | collagen, type III, alpha 1 |
| CSN3 | casein kappa |
| CTSZ | cathepsin Z |
| DCTN2 | dynactin 2 (p50) |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 |
| DOK4 | docking protein 4 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| EPHB6 | EPH receptor B6 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| ESR1 | estrogen receptor 1 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GDF5 | growth differentiation factor 5 |
| GPR75 | G protein-coupled receptor 75 |
| GTPBP1 | GTP binding protein 1 |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HIST1H3I | histone cluster 1, H3i |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| IFI16 | interferon, gamma-inducible protein 16 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNA14 | interferon, alpha 14 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| IL1RN | interleukin 1 receptor antagonist |
| IL22RA1 | interleukin 22 receptor, alpha 1 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITGB7 | integrin, beta 7 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KLF12 | Kruppel-like factor 12 |
| KLF13 | Kruppel-like factor 13 |
| KLK13 | kallikrein-related peptidase 13 |
| MEF2C | myocyte enhancer factor 2C |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MRAS | muscle RAS oncogene homolog |
| MRC2 | mannose receptor, C type 2 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NCOR2 | nuclear receptor corepressor 2 |
| NRN1 | neuritin 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PAX2 | paired box 2 |
| PCDH12 | protocadherin 12 |
| PCDHB17P | protocadherin beta 17 pseudogene |
| PCDHGA3 | protocadherin gamma subfamily A, 3 |
| PDE9A | phosphodiesterase 9A |
| PER2 | period circadian clock 2 |
| PGR | progesterone receptor |
| PIGR | polymeric immunoglobulin receptor |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRKD1 | protein kinase D1 |
| PRKD3 | protein kinase D3 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTGDR2 | prostaglandin D2 receptor 2 |
| PTHLH | parathyroid hormone-like hormone |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RBM12B | RNA binding motif protein 12B |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| SDC3 | syndecan 3 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLA | Src-like-adaptor |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SRPK2 | SRSF protein kinase 2 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ADM | adrenomedullin |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| AHSP | alpha hemoglobin stabilizing protein |
| ALPK1 | alpha-kinase 1 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARRB1 | arrestin, beta 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C3 | complement component 3 |
| C5AR2 | complement component 5a receptor 2 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC69 | coiled-coil domain containing 69 |
| CD82 | CD82 molecule |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLSTN2 | calsyntenin 2 |
| CPA4 | carboxypeptidase A4 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CXXC4 | CXXC finger protein 4 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EFNA3 | ephrin-A3 |
| EXO5 | exonuclease 5 |
| EXOC6B | exocyst complex component 6B |
| FAM76A | family with sequence similarity 76, member A |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FER | fer (fps/fes related) tyrosine kinase |
| FMOD | fibromodulin |
| FOXI1 | forkhead box I1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPATCH2L | G patch domain containing 2-like |
| GPR21 | G protein-coupled receptor 21 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H2BM | histone cluster 1, H2bm |
| HOXA4 | homeobox A4 |
| HOXC8 | homeobox C8 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| INHA | inhibin, alpha |
| INO80D | INO80 complex subunit D |
| KLHL21 | kelch-like family member 21 |
| KRT24 | keratin 24, type I |
| LOXL3 | lysyl oxidase-like 3 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LTC4S | leukotriene C4 synthase |
| MALL | mal, T-cell differentiation protein-like |
| MAPK10 | mitogen-activated protein kinase 10 |
| MBTD1 | mbt domain containing 1 |
| MVP | major vault protein |
| NIPAL2 | NIPA-like domain containing 2 |
| NME5 | NME/NM23 family member 5 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRPH | peripherin |
| PRR14L | proline rich 14-like |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RPL10L | ribosomal protein L10-like |
| SCD5 | stearoyl-CoA desaturase 5 |
| SETD1A | SET domain containing 1A |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TEX40 | testis expressed 40 |
| TMEM53 | transmembrane protein 53 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TPK1 | thiamin pyrophosphokinase 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS9D1 | VPS9 domain containing 1 |
| YY2 | YY2 transcription factor |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF76 | zinc finger protein 76 |
