| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the flumequine-5104 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ADCY1 | adenylate cyclase 1 (brain) |
| ADCY2 | adenylate cyclase 2 (brain) |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| ADORA1 | adenosine A1 receptor |
| AIF1 | allograft inflammatory factor 1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| APC | adenomatous polyposis coli |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CA1 | carbonic anhydrase I |
| CACFD1 | calcium channel flower domain containing 1 |
| CADM3 | cell adhesion molecule 3 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD247 | CD247 molecule |
| CD5 | CD5 molecule |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLEC3B | C-type lectin domain family 3, member B |
| COL11A2 | collagen, type XI, alpha 2 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CST4 | cystatin S |
| DAGLA | diacylglycerol lipase, alpha |
| DEPDC5 | DEP domain containing 5 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DRD2 | dopamine receptor D2 |
| EXOC6B | exocyst complex component 6B |
| GAB1 | GRB2-associated binding protein 1 |
| GAP43 | growth associated protein 43 |
| GLRA3 | glycine receptor, alpha 3 |
| GOLGA6A | golgin A6 family, member A |
| GPATCH4 | G patch domain containing 4 |
| GPR19 | G protein-coupled receptor 19 |
| GPR68 | G protein-coupled receptor 68 |
| GRIK2 | glutamate receptor, ionotropic, kainate 2 |
| GYPB | glycophorin B (MNS blood group) |
| HDAC11 | histone deacetylase 11 |
| HDAC6 | histone deacetylase 6 |
| HIC2 | hypermethylated in cancer 2 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HNF1B | HNF1 homeobox B |
| HOXB6 | homeobox B6 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFNA16 | interferon, alpha 16 |
| IGFBP1 | insulin-like growth factor binding protein 1 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| ITGA7 | integrin, alpha 7 |
| JUND | jun D proto-oncogene |
| KIF25 | kinesin family member 25 |
| KLK13 | kallikrein-related peptidase 13 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LHX2 | LIM homeobox 2 |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| METTL7A | methyltransferase like 7A |
| MFAP3L | microfibrillar-associated protein 3-like |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MYRF | myelin regulatory factor |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NCOR2 | nuclear receptor corepressor 2 |
| NGDN | neuroguidin, EIF4E binding protein |
| NRF1 | nuclear respiratory factor 1 |
| NRXN2 | neurexin 2 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PMEL | premelanosome protein |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PTEN | phosphatase and tensin homolog |
| PTK2B | protein tyrosine kinase 2 beta |
| RHO | rhodopsin |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RND2 | Rho family GTPase 2 |
| SAMD4B | sterile alpha motif domain containing 4B |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SH2D2A | SH2 domain containing 2A |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SYK | spleen tyrosine kinase |
| TBX2 | T-box 2 |
| TMEM246 | transmembrane protein 246 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| TYRO3 | TYRO3 protein tyrosine kinase |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VCL | vinculin |
| VEZT | vezatin, adherens junctions transmembrane protein |
| ZNF235 | zinc finger protein 235 |
| ZNF747 | zinc finger protein 747 |
| ZNF768 | zinc finger protein 768 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| APOLD1 | apolipoprotein L domain containing 1 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BAG4 | BCL2-associated athanogene 4 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BMP15 | bone morphogenetic protein 15 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CCDC69 | coiled-coil domain containing 69 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNT1 | cyclin T1 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CISH | cytokine inducible SH2-containing protein |
| CLDN15 | claudin 15 |
| CLSPN | claspin |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM186A | family with sequence similarity 186, member A |
| FCF1 | FCF1 rRNA-processing protein |
| FER | fer (fps/fes related) tyrosine kinase |
| FXN | frataxin |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLCE | glucuronic acid epimerase |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3C | histone cluster 1, H3c |
| HOXC4 | homeobox C4 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT54 | intraflagellar transport 54 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIAA0754 | KIAA0754 |
| KIAA1107 | KIAA1107 |
| KIAA1462 | KIAA1462 |
| KIRREL | kin of IRRE like (Drosophila) |
| KLF13 | Kruppel-like factor 13 |
| KLF2 | Kruppel-like factor 2 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMNB1 | lamin B1 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC390998 | ribosomal protein L10 pseudogene |
| LYRM2 | LYR motif containing 2 |
| MAGEH1 | melanoma antigen family H1 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| NCS1 | neuronal calcium sensor 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOL10 | nucleolar protein 10 |
| NPY1R | neuropeptide Y receptor Y1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSR2 | odd-skipped related transciption factor 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| POLL | polymerase (DNA directed), lambda |
| PRR7 | proline rich 7 (synaptic) |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RECQL4 | RecQ protein-like 4 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMAD5 | SMAD family member 5 |
| STEAP4 | STEAP family member 4 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM209 | transmembrane protein 209 |
| TMEM242 | transmembrane protein 242 |
| TMEM8B | transmembrane protein 8B |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TRIM25 | tripartite motif containing 25 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF606 | zinc finger protein 606 |
| ZNF671 | zinc finger protein 671 |
| ZNF675 | zinc finger protein 675 |
| ZNF816 | zinc finger protein 816 |
