| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the flumequine-5529 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADCY6 | adenylate cyclase 6 |
| AK1 | adenylate kinase 1 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| APOE | apolipoprotein E |
| APOLD1 | apolipoprotein L domain containing 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATXN2L | ataxin 2-like |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BCR | breakpoint cluster region |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CEP68 | centrosomal protein 68kDa |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| DSCAM | Down syndrome cell adhesion molecule |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| FBXO4 | F-box protein 4 |
| FGF16 | fibroblast growth factor 16 |
| FGFR4 | fibroblast growth factor receptor 4 |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPC4 | glypican 4 |
| GPR3 | G protein-coupled receptor 3 |
| GPR85 | G protein-coupled receptor 85 |
| GRM7 | glutamate receptor, metabotropic 7 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSTP1 | glutathione S-transferase pi 1 |
| HAL | histidine ammonia-lyase |
| HIPK2 | homeodomain interacting protein kinase 2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFT38 | intraflagellar transport 38 |
| IL9R | interleukin 9 receptor |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KIAA0754 | KIAA0754 |
| KIF1C | kinesin family member 1C |
| KIR2DL4 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 |
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 |
| LBP | lipopolysaccharide binding protein |
| LIMD1 | LIM domains containing 1 |
| LMF1 | lipase maturation factor 1 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LRRC75B | leucine rich repeat containing 75B |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MTA1 | metastasis associated 1 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NBEAL2 | neurobeachin-like 2 |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NPAP1 | nuclear pore associated protein 1 |
| NRIP3 | nuclear receptor interacting protein 3 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PCDHB3 | protocadherin beta 3 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE8B | phosphodiesterase 8B |
| PDZD2 | PDZ domain containing 2 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PRKCH | protein kinase C, eta |
| PRMT2IP | PRMT2 interacting protein |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RAP2A | RAP2A, member of RAS oncogene family |
| RBM26 | RNA binding motif protein 26 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SH2D2A | SH2 domain containing 2A |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMAD4 | SMAD family member 4 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| STATH | statherin |
| STX1A | syntaxin 1A (brain) |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM63A | transmembrane protein 63A |
| TMPRSS11D | transmembrane protease, serine 11D |
| TPSD1 | tryptase delta 1 |
| VAMP5 | vesicle-associated membrane protein 5 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF783 | zinc finger family member 783 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| APH1B | APH1B gamma secretase subunit |
| ATG2A | autophagy related 2A |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C5 | complement component 5 |
| CCNJ | cyclin J |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CENPO | centromere protein O |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CPTP | ceramide-1-phosphate transfer protein |
| CTC1 | CTS telomere maintenance complex component 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ETNK2 | ethanolamine kinase 2 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM120C | family with sequence similarity 120C |
| FAM50B | family with sequence similarity 50, member B |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GID4 | GID complex subunit 4 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GOLGA8B | golgin A8 family, member B |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4D | histone cluster 1, H4d |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KLK5 | kallikrein-related peptidase 5 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| NARFL | nuclear prelamin A recognition factor-like |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) |
| NECAP2 | NECAP endocytosis associated 2 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| ONECUT2 | one cut homeobox 2 |
| OPN3 | opsin 3 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PCDHA9 | protocadherin alpha 9 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| PRPH | peripherin |
| PVRL3 | poliovirus receptor-related 3 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIN2 | Ras and Rab interactor 2 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF122 | ring finger protein 122 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF170 | ring finger protein 170 |
| RNF2 | ring finger protein 2 |
| RNF25 | ring finger protein 25 |
| ROM1 | retinal outer segment membrane protein 1 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 |
| SPIDR | scaffolding protein involved in DNA repair |
| SREK1IP1 | SREK1-interacting protein 1 |
| STBD1 | starch binding domain 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAOK1 | TAO kinase 1 |
| TLR5 | toll-like receptor 5 |
| TMEM180 | transmembrane protein 180 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| YEATS2 | YEATS domain containing 2 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF282 | zinc finger protein 282 |
| ZNF408 | zinc finger protein 408 |
| ZNF446 | zinc finger protein 446 |
| ZNF606 | zinc finger protein 606 |
