flumetasone-3410 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the flumetasone-3410 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
AGFG2 ArfGAP with FG repeats 2
AMPD3 adenosine monophosphate deaminase 3
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BATF3 basic leucine zipper transcription factor, ATF-like 3
BIN1 bridging integrator 1
BIRC7 baculoviral IAP repeat containing 7
BMP2K BMP2 inducible kinase
BTG2 BTG family, member 2
C17ORF59 chromosome 17 open reading frame 59
C2CD2L C2CD2-like
C9ORF156 chromosome 9 open reading frame 156
CALML3 calmodulin-like 3
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC42 cell division cycle 42
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFLAR CASP8 and FADD-like apoptosis regulator
COL5A1 collagen, type V, alpha 1
CSF1 colony stimulating factor 1 (macrophage)
CYHR1 cysteine/histidine-rich 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DAPK3 death-associated protein kinase 3
DIXDC1 DIX domain containing 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPYSL4 dihydropyrimidinase-like 4
DUSP10 dual specificity phosphatase 10
E2F5 E2F transcription factor 5, p130-binding
ELP6 elongator acetyltransferase complex subunit 6
ELSPBP1 epididymal sperm binding protein 1
EML3 echinoderm microtubule associated protein like 3
EPN2 epsin 2
ERN2 endoplasmic reticulum to nucleus signaling 2
EVA1B eva-1 homolog B (C. elegans)
EXOC7 exocyst complex component 7
FAM189A2 family with sequence similarity 189, member A2
FBXL6 F-box and leucine-rich repeat protein 6
FMOD fibromodulin
GRIK5 glutamate receptor, ionotropic, kainate 5
GRK5 G protein-coupled receptor kinase 5
HEXIM1 hexamethylene bis-acetamide inducible 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
ICAM1 intercellular adhesion molecule 1
IFT54 intraflagellar transport 54
IGFBP5 insulin-like growth factor binding protein 5
IGLJ3 immunoglobulin lambda joining 3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
INCENP inner centromere protein antigens 135/155kDa
KLHL20 kelch-like family member 20
KRT6B keratin 6B, type II
LINC00115 long intergenic non-protein coding RNA 115
LPPR1 lipid phosphate phosphatase-related protein type 1
MAGOH2P mago-nashi homolog 2, pseudogene
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MIR622 microRNA 622
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MXD4 MAX dimerization protein 4
MYL10 myosin, light chain 10, regulatory
MYO1B myosin IB
NF2 neurofibromin 2 (merlin)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRGN neurogranin (protein kinase C substrate, RC3)
NUP50 nucleoporin 50kDa
OVOL1 ovo-like zinc finger 1
PCDHGA10 protocadherin gamma subfamily A, 10
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PRDM2 PR domain containing 2, with ZNF domain
PRSS53 protease, serine, 53
PSD4 pleckstrin and Sec7 domain containing 4
RAB3D RAB3D, member RAS oncogene family
RGS12 regulator of G-protein signaling 12
RHEB Ras homolog enriched in brain
RHOBTB2 Rho-related BTB domain containing 2
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
STK24 serine/threonine kinase 24
STRN striatin, calmodulin binding protein
STYK1 serine/threonine/tyrosine kinase 1
SURF1 surfeit 1
SZT2 seizure threshold 2 homolog (mouse)
TAOK1 TAO kinase 1
TCP11L1 t-complex 11, testis-specific-like 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
VGF VGF nerve growth factor inducible
WDFY3 WD repeat and FYVE domain containing 3
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF136 zinc finger protein 136
ZNF277 zinc finger protein 277
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ADRA2C adrenoceptor alpha 2C
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGAP10 Rho GTPase activating protein 10
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAK1 BCL2-antagonist/killer 1
BBS1 Bardet-Biedl syndrome 1
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BCL2L2 BCL2-like 2
BCORL1 BCL6 corepressor-like 1
BFSP1 beaded filament structural protein 1, filensin
C2ORF44 chromosome 2 open reading frame 44
CEP131 centrosomal protein 131kDa
CEP70 centrosomal protein 70kDa
CEP72 centrosomal protein 72kDa
CHML choroideremia-like (Rab escort protein 2)
CHRM3 cholinergic receptor, muscarinic 3
CIC capicua transcriptional repressor
CINP cyclin-dependent kinase 2 interacting protein
CISH cytokine inducible SH2-containing protein
CLCN2 chloride channel, voltage-sensitive 2
CLSTN1 calsyntenin 1
COL9A2 collagen, type IX, alpha 2
CRBN cereblon
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DGKD diacylglycerol kinase, delta 130kDa
ECHDC2 enoyl CoA hydratase domain containing 2
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
FAM111A family with sequence similarity 111, member A
FBP1 fructose-1,6-bisphosphatase 1
FBXO31 F-box protein 31
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FPGS folylpolyglutamate synthase
FSD1 fibronectin type III and SPRY domain containing 1
GALK1 galactokinase 1
GDAP1 ganglioside induced differentiation associated protein 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HINFP histone H4 transcription factor
HIRA histone cell cycle regulator
HIST1H2BJ histone cluster 1, H2bj
ICK intestinal cell (MAK-like) kinase
IL17RA interleukin 17 receptor A
IP6K1 inositol hexakisphosphate kinase 1
KCTD7 potassium channel tetramerization domain containing 7
KLHL36 kelch-like family member 36
KRT13 keratin 13, type I
LAMB2 laminin, beta 2 (laminin S)
LIN7A lin-7 homolog A (C. elegans)
LINC00339 long intergenic non-protein coding RNA 339
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP5L low density lipoprotein receptor-related protein 5-like
LZTR1 leucine-zipper-like transcription regulator 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MGC12488
NABP2 nucleic acid binding protein 2
NARFL nuclear prelamin A recognition factor-like
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEIL3 nei endonuclease VIII-like 3 (E. coli)
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAQR4 progestin and adipoQ receptor family member IV
PAQR6 progestin and adipoQ receptor family member VI
PCBP4 poly(rC) binding protein 4
PHC1 polyhomeotic homolog 1 (Drosophila)
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMEPA1 prostate transmembrane protein, androgen induced 1
PTK6 protein tyrosine kinase 6
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
SDAD1 SDA1 domain containing 1
SH2B3 SH2B adaptor protein 3
SIRT2 sirtuin 2
SIRT6 sirtuin 6
SKA1 spindle and kinetochore associated complex subunit 1
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC46A3 solute carrier family 46, member 3
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SSFA2 sperm specific antigen 2
STBD1 starch binding domain 1
TARP TCR gamma alternate reading frame protein
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TWF2 twinfilin actin binding protein 2
UBQLN4 ubiquilin 4
VEGFC vascular endothelial growth factor C
WDR47 WD repeat domain 47
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZFHX3 zinc finger homeobox 3
ZNF350 zinc finger protein 350
ZNF365 zinc finger protein 365
ZNF552 zinc finger protein 552