flumetasone-3610 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the flumetasone-3610 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ADCK4 aarF domain containing kinase 4
ADCY10 adenylate cyclase 10 (soluble)
AFF2 AF4/FMR2 family, member 2
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ARTN artemin
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C14ORF79 chromosome 14 open reading frame 79
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCR8 chemokine (C-C motif) receptor 8
CDK18 cyclin-dependent kinase 18
COL11A1 collagen, type XI, alpha 1
COL2A1 collagen, type II, alpha 1
CRTC1 CREB regulated transcription coactivator 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DNASE2B deoxyribonuclease II beta
DOCK5 dedicator of cytokinesis 5
DUSP6 dual specificity phosphatase 6
ECM1 extracellular matrix protein 1
EFR3B EFR3 homolog B (S. cerevisiae)
EGR4 early growth response 4
EMP1 epithelial membrane protein 1
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
ERCC2 excision repair cross-complementation group 2
FGFR1 fibroblast growth factor receptor 1
FOLR2 folate receptor 2 (fetal)
GAS7 growth arrest-specific 7
GK glycerol kinase
GLP1R glucagon-like peptide 1 receptor
GLRA3 glycine receptor, alpha 3
GLYAT glycine-N-acyltransferase
GP1BB glycoprotein Ib (platelet), beta polypeptide
GPR137 G protein-coupled receptor 137
GREB1L growth regulation by estrogen in breast cancer-like
GTPBP1 GTP binding protein 1
HEMK1 HemK methyltransferase family member 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HHLA1 HERV-H LTR-associating 1
HKDC1 hexokinase domain containing 1
HSF2BP heat shock transcription factor 2 binding protein
IFI27 interferon, alpha-inducible protein 27
IL1RN interleukin 1 receptor antagonist
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
IVL involucrin
KIAA0226L KIAA0226-like
KIAA1024 KIAA1024
KRT8 keratin 8, type II
LBH limb bud and heart development
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMCH1 LIM and calponin homology domains 1
LINC00652 long intergenic non-protein coding RNA 652
LTK leukocyte receptor tyrosine kinase
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MST1 macrophage stimulating 1
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
NCOR2 nuclear receptor corepressor 2
NF1 neurofibromin 1
PAX8 paired box 8
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PER1 period circadian clock 1
PHF1 PHD finger protein 1
PIDD1 p53-induced death domain protein 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G3 phospholipase A2, group III
PLAC4 placenta-specific 4
PLIN2 perilipin 2
PML promyelocytic leukemia
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRLH prolactin releasing hormone
PSCA prostate stem cell antigen
RASIP1 Ras interacting protein 1
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RHOBTB2 Rho-related BTB domain containing 2
RND1 Rho family GTPase 1
RNF39 ring finger protein 39
SERHL2 serine hydrolase-like 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMR3A submaxillary gland androgen regulated protein 3A
SPARCL1 SPARC-like 1 (hevin)
SPHK2 sphingosine kinase 2
SSX3 synovial sarcoma, X breakpoint 3
STS steroid sulfatase (microsomal), isozyme S
SWAP70 SWAP switching B-cell complex 70kDa subunit
T T, brachyury homolog (mouse)
TERT telomerase reverse transcriptase
TRH thyrotropin-releasing hormone
TRIM10 tripartite motif containing 10
TRIM31 tripartite motif containing 31
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UNC5B unc-5 homolog B (C. elegans)
ZIM2 zinc finger, imprinted 2
ZNF154 zinc finger protein 154
ZNF423 zinc finger protein 423
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARHGAP4 Rho GTPase activating protein 4
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASAP1-IT1 ASAP1 intronic transcript 1
C11ORF21 chromosome 11 open reading frame 21
C17ORF53 chromosome 17 open reading frame 53
C19ORF73 chromosome 19 open reading frame 73
C9ORF9 chromosome 9 open reading frame 9
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK4 calcium/calmodulin-dependent protein kinase IV
CFAP70 cilia and flagella associated protein 70
CHM choroideremia (Rab escort protein 1)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EFNA3 ephrin-A3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPN1 epsin 1
ERCC4 excision repair cross-complementation group 4
FADS2 fatty acid desaturase 2
FAM131A family with sequence similarity 131, member A
FAM46C family with sequence similarity 46, member C
FGF13 fibroblast growth factor 13
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLT4 fms-related tyrosine kinase 4
FNTB farnesyltransferase, CAAX box, beta
FURIN furin (paired basic amino acid cleaving enzyme)
GAMT guanidinoacetate N-methyltransferase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH2L G patch domain containing 2-like
GPR19 G protein-coupled receptor 19
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF2I general transcription factor IIi
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H1E histone cluster 1, H1e
HIST1H3E histone cluster 1, H3e
HIST1H4A histone cluster 1, H4a
HIST1H4F histone cluster 1, H4f
IFNA17 interferon, alpha 17
IFT140 intraflagellar transport 140
IL12RB1 interleukin 12 receptor, beta 1
IQSEC2 IQ motif and Sec7 domain 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCTD20 potassium channel tetramerization domain containing 20
KIAA1107 KIAA1107
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRI1 KRI1 homolog (S. cerevisiae)
LIF leukemia inhibitory factor
LONRF3 LON peptidase N-terminal domain and ring finger 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM4 MDM4, p53 regulator
MNX1 motor neuron and pancreas homeobox 1
MOB3B MOB kinase activator 3B
MRPS18C mitochondrial ribosomal protein S18C
MTERF4 mitochondrial transcription termination factor 4
MVP major vault protein
NPY4R neuropeptide Y receptor Y4
OSGIN1 oxidative stress induced growth inhibitor 1
PCBP4 poly(rC) binding protein 4
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR4 proline rich 4 (lacrimal)
RAB3A RAB3A, member RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHBDD3 rhomboid domain containing 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIBC2 RIB43A domain with coiled-coils 2
RIC8B RIC8 guanine nucleotide exchange factor B
RNF126P1 ring finger protein 126 pseudogene 1
RPGRIP1L RPGRIP1-like
SDS serine dehydratase
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLIT2 slit homolog 2 (Drosophila)
SNORA21 small nucleolar RNA, H/ACA box 21
SORBS3 sorbin and SH3 domain containing 3
STX1A syntaxin 1A (brain)
TARP TCR gamma alternate reading frame protein
TBC1D19 TBC1 domain family, member 19
TBKBP1 TBK1 binding protein 1
TCTA T-cell leukemia translocation altered
TGFBR3 transforming growth factor, beta receptor III
TMEM209 transmembrane protein 209
TRAIP TRAF interacting protein
TRDMT1 tRNA aspartic acid methyltransferase 1
TSC22D4 TSC22 domain family, member 4
UBTD1 ubiquitin domain containing 1
VASH2 vasohibin 2
VIM vimentin
VIPR1 vasoactive intestinal peptide receptor 1
XDH xanthine dehydrogenase
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YY2 YY2 transcription factor
ZNRD1-AS1 ZNRD1 antisense RNA 1