flumetasone-4272 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the flumetasone-4272 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANGPTL2 angiopoietin-like 2
ANK1 ankyrin 1, erythrocytic
APOC1 apolipoprotein C-I
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARID5A AT rich interactive domain 5A (MRF1-like)
ATN1 atrophin 1
ATP11A ATPase, class VI, type 11A
BCL2L1 BCL2-like 1
C7ORF26 chromosome 7 open reading frame 26
CA1 carbonic anhydrase I
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CALML3 calmodulin-like 3
CD40 CD40 molecule, TNF receptor superfamily member 5
CDRT1 CMT1A duplicated region transcript 1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CNTD2 cyclin N-terminal domain containing 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DMXL2 Dmx-like 2
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOK4 docking protein 4
DUOX1 dual oxidase 1
DUSP1 dual specificity phosphatase 1
EFNB1 ephrin-B1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EMID1 EMI domain containing 1
FBXO41 F-box protein 41
FGF22 fibroblast growth factor 22
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GH1 growth hormone 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GREB1L growth regulation by estrogen in breast cancer-like
GRK5 G protein-coupled receptor kinase 5
GRM4 glutamate receptor, metabotropic 4
HCFC1 host cell factor C1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGA1 high mobility group AT-hook 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
ICAM5 intercellular adhesion molecule 5, telencephalin
IGLJ3 immunoglobulin lambda joining 3
IL1R2 interleukin 1 receptor, type II
IRF4 interferon regulatory factor 4
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KERA keratocan
LDB3 LIM domain binding 3
LRRN2 leucine rich repeat neuronal 2
MAP3K19 mitogen-activated protein kinase kinase kinase 19
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MEGF8 multiple EGF-like-domains 8
MINK1 misshapen-like kinase 1
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP25 matrix metallopeptidase 25
MTA1 metastasis associated 1
MYH14 myosin, heavy chain 14, non-muscle
NCOR2 nuclear receptor corepressor 2
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NNMT nicotinamide N-methyltransferase
PCDHA5 protocadherin alpha 5
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDE4A phosphodiesterase 4A, cAMP-specific
PECAM1 platelet/endothelial cell adhesion molecule 1
PLAT plasminogen activator, tissue
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PTAFR platelet-activating factor receptor
PTGDS prostaglandin D2 synthase 21kDa (brain)
PXN paxillin
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RARG retinoic acid receptor, gamma
RB1 retinoblastoma 1
RERE arginine-glutamic acid dipeptide (RE) repeats
RGS12 regulator of G-protein signaling 12
ROPN1B rhophilin associated tail protein 1B
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
SAFB2 scaffold attachment factor B2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SEC14L2 SEC14-like 2 (S. cerevisiae)
SFTPB surfactant protein B
SIRPA signal-regulatory protein alpha
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SORBS3 sorbin and SH3 domain containing 3
SOX2 SRY (sex determining region Y)-box 2
SRF serum response factor (c-fos serum response element-binding transcription factor)
TAPBPL TAP binding protein-like
TEX13B testis expressed 13B
TNNC2 troponin C type 2 (fast)
TNS4 tensin 4
TP53I11 tumor protein p53 inducible protein 11
TRIM3 tripartite motif containing 3
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TUBB7P tubulin, beta 7, pseudogene
TYR tyrosinase
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZFHX3 zinc finger homeobox 3
ZNF280A zinc finger protein 280A

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ALPK1 alpha-kinase 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANAPC10 anaphase promoting complex subunit 10
ASB13 ankyrin repeat and SOCS box containing 13
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD5 ATPase family, AAA domain containing 5
C16ORF59 chromosome 16 open reading frame 59
CCNT1 cyclin T1
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CFAP44 cilia and flagella associated protein 44
CLDN14 claudin 14
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
DBF4B DBF4 zinc finger B
DCAF13 DDB1 and CUL4 associated factor 13
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DEPDC1 DEP domain containing 1
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNAAF2 dynein, axonemal, assembly factor 2
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
EDC4 enhancer of mRNA decapping 4
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
FAM204A family with sequence similarity 204, member A
FAM8A1 family with sequence similarity 8, member A1
FCGRT Fc fragment of IgG, receptor, transporter, alpha
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GLDC glycine dehydrogenase (decarboxylating)
GRPR gastrin-releasing peptide receptor
GSTT1 glutathione S-transferase theta 1
HIST1H1D histone cluster 1, H1d
HIST1H4C histone cluster 1, H4c
IDI2-AS1 IDI2 antisense RNA 1
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IL33 interleukin 33
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0754 KIAA0754
KIAA1107 KIAA1107
LINC00597 long intergenic non-protein coding RNA 597
LMNB1 lamin B1
LMO7 LIM domain 7
LPGAT1 lysophosphatidylglycerol acyltransferase 1
MAGEA6 melanoma antigen family A6
MAGOHB mago-nashi homolog B (Drosophila)
MIS12 MIS12 kinetochore complex component
MOXD1 monooxygenase, DBH-like 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MXD3 MAX dimerization protein 3
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NHLRC2 NHL repeat containing 2
NID2 nidogen 2 (osteonidogen)
NMB neuromedin B
NPY1R neuropeptide Y receptor Y1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NUBPL nucleotide binding protein-like
NUPR1 nuclear protein, transcriptional regulator, 1
NUTF2 nuclear transport factor 2
OXR1 oxidation resistance 1
PBLD phenazine biosynthesis-like protein domain containing
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDZK1 PDZ domain containing 1
PLA2G12A phospholipase A2, group XIIA
POMT2 protein-O-mannosyltransferase 2
PPT2 palmitoyl-protein thioesterase 2
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKX protein kinase, X-linked
PRR4 proline rich 4 (lacrimal)
PTBP2 polypyrimidine tract binding protein 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPS14P3 ribosomal protein S14 pseudogene 3
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RRAGB Ras-related GTP binding B
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SERINC5 serine incorporator 5
SLC31A1 solute carrier family 31 (copper transporter), member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNX16 sorting nexin 16
SPATS2 spermatogenesis associated, serine-rich 2
SPIN1 spindlin 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAGLN3 transgelin 3
TMEM2 transmembrane protein 2
TTF2 transcription termination factor, RNA polymerase II
ULBP2 UL16 binding protein 2
USP27X ubiquitin specific peptidase 27, X-linked
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
WDR43 WD repeat domain 43
YIPF1 Yip1 domain family, member 1
ZBTB3 zinc finger and BTB domain containing 3
ZNF230 zinc finger protein 230
ZNF432 zinc finger protein 432