| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the flunarizine-7252 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATXN3 | ataxin 3 |
| B9D1 | B9 protein domain 1 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CHM | choroideremia (Rab escort protein 1) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLEC2B | C-type lectin domain family 2, member B |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DUSP10 | dual specificity phosphatase 10 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EGF | epidermal growth factor |
| EPHB2 | EPH receptor B2 |
| FAM131B | family with sequence similarity 131, member B |
| FAM173A | family with sequence similarity 173, member A |
| FAM69A | family with sequence similarity 69, member A |
| FLOT2 | flotillin 2 |
| FLT1 | fms-related tyrosine kinase 1 |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| GALK2 | galactokinase 2 |
| GON4L | gon-4-like (C. elegans) |
| GPATCH2L | G patch domain containing 2-like |
| GSAP | gamma-secretase activating protein |
| GTPBP1 | GTP binding protein 1 |
| HOXB2 | homeobox B2 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| ITM2B | integral membrane protein 2B |
| LDB1 | LIM domain binding 1 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MBTD1 | mbt domain containing 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MED13L | mediator complex subunit 13-like |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| NNT | nicotinamide nucleotide transhydrogenase |
| NRXN3 | neurexin 3 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PEX7 | peroxisomal biogenesis factor 7 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIDD1 | p53-induced death domain protein 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRMT2 | protein arginine methyltransferase 2 |
| QKI | QKI, KH domain containing, RNA binding |
| RAB2A | RAB2A, member RAS oncogene family |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RGS4 | regulator of G-protein signaling 4 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF19B | ring finger protein 19B |
| RPAIN | RPA interacting protein |
| S100A3 | S100 calcium binding protein A3 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNPH | syntaphilin |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STS | steroid sulfatase (microsomal), isozyme S |
| STX6 | syntaxin 6 |
| TAPBP | TAP binding protein (tapasin) |
| TCTN1 | tectonic family member 1 |
| TEX40 | testis expressed 40 |
| TFR2 | transferrin receptor 2 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TK2 | thymidine kinase 2, mitochondrial |
| TLK1 | tousled-like kinase 1 |
| TMEM242 | transmembrane protein 242 |
| TMEM8B | transmembrane protein 8B |
| TOR1AIP1 | torsin A interacting protein 1 |
| TRIM25 | tripartite motif containing 25 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSFM | Ts translation elongation factor, mitochondrial |
| TUBG2 | tubulin, gamma 2 |
| ULBP2 | UL16 binding protein 2 |
| USP24 | ubiquitin specific peptidase 24 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF200 | zinc finger protein 200 |
| ZNF45 | zinc finger protein 45 |
| Symbol | Name |
|---|---|
| ARMC6 | armadillo repeat containing 6 |
| ASS1 | argininosuccinate synthase 1 |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| BCAS4 | breast carcinoma amplified sequence 4 |
| BRD1 | bromodomain containing 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF112 | chromosome 1 open reading frame 112 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHKB | choline kinase beta |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN3 | claudin 3 |
| CLSPN | claspin |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTAGE9 | CTAGE family, member 9 |
| CUL9 | cullin 9 |
| DGKZ | diacylglycerol kinase, zeta |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| EDC3 | enhancer of mRNA decapping 3 |
| EFNA1 | ephrin-A1 |
| EN1 | engrailed homeobox 1 |
| ETV4 | ets variant 4 |
| EXOC3 | exocyst complex component 3 |
| FAM188A | family with sequence similarity 188, member A |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FKBPL | FK506 binding protein like |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FPGS | folylpolyglutamate synthase |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GCA | grancalcin, EF-hand calcium binding protein |
| GLCE | glucuronic acid epimerase |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H2AJ | histone cluster 1, H2aj |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXC8 | homeobox C8 |
| ICK | intestinal cell (MAK-like) kinase |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| KLF11 | Kruppel-like factor 11 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LMBR1L | limb development membrane protein 1-like |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MACROD1 | MACRO domain containing 1 |
| MAN2B2 | mannosidase, alpha, class 2B, member 2 |
| MEIS1 | Meis homeobox 1 |
| METTL2B | methyltransferase like 2B |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MPC1 | mitochondrial pyruvate carrier 1 |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYLK | myosin light chain kinase |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDE1 | nudE neurodevelopment protein 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| ODF2 | outer dense fiber of sperm tails 2 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PARD6A | par-6 family cell polarity regulator alpha |
| PEX26 | peroxisomal biogenesis factor 26 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| POLH | polymerase (DNA directed), eta |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 |
| RNF121 | ring finger protein 121 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF25 | ring finger protein 25 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPGR | retinitis pigmentosa GTPase regulator |
| SESN1 | sestrin 1 |
| SIK1 | salt-inducible kinase 1 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SPATA7 | spermatogenesis associated 7 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| SYTL2 | synaptotagmin-like 2 |
| TGFBR3 | transforming growth factor, beta receptor III |
| THAP1 | THAP domain containing, apoptosis associated protein 1 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM62 | transmembrane protein 62 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TTC26 | tetratricopeptide repeat domain 26 |
| UBQLN4 | ubiquilin 4 |
| USP6NL | USP6 N-terminal like |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF107 | zinc finger protein 107 |
| ZNF180 | zinc finger protein 180 |
| ZNF415 | zinc finger protein 415 |
| ZNF574 | zinc finger protein 574 |
