flunisolide-3747 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the flunisolide-3747 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACTC1 actin, alpha, cardiac muscle 1
ACVR1B activin A receptor, type IB
ADAM11 ADAM metallopeptidase domain 11
ADCK2 aarF domain containing kinase 2
ANGPTL4 angiopoietin-like 4
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
C5ORF45 chromosome 5 open reading frame 45
CCDC170 coiled-coil domain containing 170
CD1E CD1e molecule
CD300C CD300c molecule
CDK13 cyclin-dependent kinase 13
CDO1 cysteine dioxygenase type 1
CLDN1 claudin 1
CNGB3 cyclic nucleotide gated channel beta 3
COL21A1 collagen, type XXI, alpha 1
CRHR2 corticotropin releasing hormone receptor 2
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DMBT1 deleted in malignant brain tumors 1
DUSP1 dual specificity phosphatase 1
EFNB3 ephrin-B3
ERC2 ELKS/RAB6-interacting/CAST family member 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ESR1 estrogen receptor 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FABP6 fatty acid binding protein 6, ileal
FAIM2 Fas apoptotic inhibitory molecule 2
FBXO22 F-box protein 22
FRMD4B FERM domain containing 4B
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GP5 glycoprotein V (platelet)
GPR25 G protein-coupled receptor 25
GTPBP1 GTP binding protein 1
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HIST1H2BL histone cluster 1, H2bl
HIST1H4F histone cluster 1, H4f
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFI27 interferon, alpha-inducible protein 27
IMPG2 interphotoreceptor matrix proteoglycan 2
IZUMO4 IZUMO family member 4
KALRN kalirin, RhoGEF kinase
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0226L KIAA0226-like
KRT33A keratin 33A, type I
MAB21L1 mab-21-like 1 (C. elegans)
MAN2A2 mannosidase, alpha, class 2A, member 2
MAPK10 mitogen-activated protein kinase 10
MAPK11 mitogen-activated protein kinase 11
MEFV Mediterranean fever
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MSLN mesothelin
MT1HL1 metallothionein 1H-like 1
MXRA5 matrix-remodelling associated 5
MYO9B myosin IXB
NEK1 NIMA-related kinase 1
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NNMT nicotinamide N-methyltransferase
NPTX1 neuronal pentraxin I
NPY2R neuropeptide Y receptor Y2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OCA2 oculocutaneous albinism II
OLAH oleoyl-ACP hydrolase
OLFM1 olfactomedin 1
OR12D3 olfactory receptor, family 12, subfamily D, member 3
PAX8 paired box 8
PDE10A phosphodiesterase 10A
PDIA2 protein disulfide isomerase family A, member 2
PDLIM3 PDZ and LIM domain 3
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKNOX2 PBX/knotted 1 homeobox 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PRLR prolactin receptor
PRY PTPN13-like, Y-linked
RAB30 RAB30, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RETN resistin
RPL7 ribosomal protein L7
SCLY selenocysteine lyase
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SDS serine dehydratase
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMO smoothened, frizzled class receptor
SPINK1 serine peptidase inhibitor, Kazal type 1
TAS2R4 taste receptor, type 2, member 4
TBCD tubulin folding cofactor D
TFDP3 transcription factor Dp family, member 3
TGM4 transglutaminase 4
TMEM74B transmembrane protein 74B
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TRADD TNFRSF1A-associated via death domain
TRIM3 tripartite motif containing 3
XAF1 XIAP associated factor 1
ZIM2 zinc finger, imprinted 2

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACAD10 acyl-CoA dehydrogenase family, member 10
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKRD36 ankyrin repeat domain 36
ARMC4 armadillo repeat containing 4
ASCC2 activating signal cointegrator 1 complex subunit 2
ATF7IP2 activating transcription factor 7 interacting protein 2
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BCAS3 breast carcinoma amplified sequence 3
BEND5 BEN domain containing 5
BMP4 bone morphogenetic protein 4
BTC betacellulin
C11ORF80 chromosome 11 open reading frame 80
C1QTNF1 C1q and tumor necrosis factor related protein 1
C4ORF29 chromosome 4 open reading frame 29
CA5BP1 carbonic anhydrase VB pseudogene 1
CCNJL cyclin J-like
CCNO cyclin O
CCNT1 cyclin T1
CEP85 centrosomal protein 85kDa
CHKB choline kinase beta
CHM choroideremia (Rab escort protein 1)
CORO1A coronin, actin binding protein, 1A
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EDN1 endothelin 1
EPHA4 EPH receptor A4
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC3 excision repair cross-complementation group 3
FBXL15 F-box and leucine-rich repeat protein 15
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GLS2 glutaminase 2 (liver, mitochondrial)
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1E histone cluster 1, H1e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA4 homeobox A4
HOXB5 homeobox B5
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL24 interleukin 24
IL7R interleukin 7 receptor
KDM7A lysine (K)-specific demethylase 7A
KIAA0513 KIAA0513
KIRREL kin of IRRE like (Drosophila)
LRRC37A3 leucine rich repeat containing 37, member A3
MANBA mannosidase, beta A, lysosomal
MFSD11 major facilitator superfamily domain containing 11
MIS18BP1 MIS18 binding protein 1
MMP3 matrix metallopeptidase 3
MVP major vault protein
MXRA8 matrix-remodelling associated 8
MYLIP myosin regulatory light chain interacting protein
NDE1 nudE neurodevelopment protein 1
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
ODF2 outer dense fiber of sperm tails 2
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OVGP1 oviductal glycoprotein 1, 120kDa
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAX9 paired box 9
PLAC8 placenta-specific 8
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POMT2 protein-O-mannosyltransferase 2
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP6R3 protein phosphatase 6, regulatory subunit 3
PTPRS protein tyrosine phosphatase, receptor type, S
QPCTL glutaminyl-peptide cyclotransferase-like
RFX7 regulatory factor X, 7
RWDD2A RWD domain containing 2A
SARS2 seryl-tRNA synthetase 2, mitochondrial
SAYSD1 SAYSVFN motif domain containing 1
SCAI suppressor of cancer cell invasion
SCYL2 SCY1-like 2 (S. cerevisiae)
SLC38A10 solute carrier family 38, member 10
SPIDR scaffolding protein involved in DNA repair
STARD3 StAR-related lipid transfer (START) domain containing 3
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TEP1 telomerase-associated protein 1
THOP1 thimet oligopeptidase 1
TMEM156 transmembrane protein 156
TMEM183A transmembrane protein 183A
TPCN1 two pore segment channel 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTLL7 tubulin tyrosine ligase-like family member 7
TWF2 twinfilin actin binding protein 2
UGT8 UDP glycosyltransferase 8
VGLL3 vestigial-like family member 3
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
YY2 YY2 transcription factor
ZBED1 zinc finger, BED-type containing 1
ZBTB22 zinc finger and BTB domain containing 22
ZMAT5 zinc finger, matrin-type 5
ZMYM3 zinc finger, MYM-type 3
ZNF140 zinc finger protein 140
ZNF205 zinc finger protein 205
ZNF227 zinc finger protein 227
ZNF611 zinc finger protein 611
ZNF768 zinc finger protein 768
ZNF862 zinc finger protein 862