flunisolide-3923 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the flunisolide-3923 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACVR1B activin A receptor, type IB
BIRC7 baculoviral IAP repeat containing 7
BLK BLK proto-oncogene, Src family tyrosine kinase
BTN2A2 butyrophilin, subfamily 2, member A2
C1ORF68 chromosome 1 open reading frame 68
CABP2 calcium binding protein 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAV3 caveolin 3
CCDC85B coiled-coil domain containing 85B
CD244 CD244 molecule, natural killer cell receptor 2B4
CD86 CD86 molecule
CDK19 cyclin-dependent kinase 19
CEP112 centrosomal protein 112kDa
CLCA2 chloride channel accessory 2
CLEC3B C-type lectin domain family 3, member B
COL1A1 collagen, type I, alpha 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CTNS cystinosin, lysosomal cystine transporter
CXCR4 chemokine (C-X-C motif) receptor 4
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DBP D site of albumin promoter (albumin D-box) binding protein
DHRS7 dehydrogenase/reductase (SDR family) member 7
DOCK6 dedicator of cytokinesis 6
DRD5 dopamine receptor D5
EFCAB6 EF-hand calcium binding domain 6
EMP1 epithelial membrane protein 1
EMX1 empty spiracles homeobox 1
EPS8L3 EPS8-like 3
EVI2B ecotropic viral integration site 2B
FABP2 fatty acid binding protein 2, intestinal
FAM66D family with sequence similarity 66, member D
FGF1 fibroblast growth factor 1 (acidic)
FGF16 fibroblast growth factor 16
FGF4 fibroblast growth factor 4
FXYD2 FXYD domain containing ion transport regulator 2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
HEXA-AS1 HEXA antisense RNA 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFNA14 interferon, alpha 14
IGF1 insulin-like growth factor 1 (somatomedin C)
KALRN kalirin, RhoGEF kinase
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KRT6B keratin 6B, type II
LGALS8 lectin, galactoside-binding, soluble, 8
LIME1 Lck interacting transmembrane adaptor 1
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MEGF8 multiple EGF-like-domains 8
MID1 midline 1
MIER2 mesoderm induction early response 1, family member 2
MMP8 matrix metallopeptidase 8
MST1R macrophage stimulating 1 receptor
MYL10 myosin, light chain 10, regulatory
NEUROD1 neuronal differentiation 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PHOX2A paired-like homeobox 2a
PHOX2B paired-like homeobox 2b
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POU6F2 POU class 6 homeobox 2
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRKCB protein kinase C, beta
PSAT1 phosphoserine aminotransferase 1
RARB retinoic acid receptor, beta
REC8 REC8 meiotic recombination protein
RECQL5 RecQ protein-like 5
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SAFB scaffold attachment factor B
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEZ6L seizure related 6 homolog (mouse)-like
SFTPB surfactant protein B
SLC39A9 solute carrier family 39, member 9
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMG7-AS1 SMG7 antisense RNA 1
SSX3 synovial sarcoma, X breakpoint 3
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TBC1D2 TBC1 domain family, member 2
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TBCD tubulin folding cofactor D
TCF3 transcription factor 3
TMEM176A transmembrane protein 176A
TMEM40 transmembrane protein 40
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNK2 tyrosine kinase, non-receptor, 2
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TUBA3C tubulin, alpha 3c
UBA6 ubiquitin-like modifier activating enzyme 6
USH1C Usher syndrome 1C (autosomal recessive, severe)
USP22 ubiquitin specific peptidase 22
VCAN versican
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZIM2 zinc finger, imprinted 2
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AEN apoptosis enhancing nuclease
AKT2 v-akt murine thymoma viral oncogene homolog 2
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATAT1 alpha tubulin acetyltransferase 1
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BBC3 BCL2 binding component 3
BGLAP bone gamma-carboxyglutamate (gla) protein
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C16ORF45 chromosome 16 open reading frame 45
CAPN15 calpain 15
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDHR2 cadherin-related family member 2
CDK18 cyclin-dependent kinase 18
CFHR4 complement factor H-related 4
CHKB choline kinase beta
CLSPN claspin
CPA4 carboxypeptidase A4
CRELD1 cysteine-rich with EGF-like domains 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DIXDC1 DIX domain containing 1
DNAL4 dynein, axonemal, light chain 4
DOCK1 dedicator of cytokinesis 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ETNK2 ethanolamine kinase 2
FBXO31 F-box protein 31
FLJ22184
FOXC1 forkhead box C1
FOXD1 forkhead box D1
GPR143 G protein-coupled receptor 143
GPRC5D G protein-coupled receptor, class C, group 5, member D
HCAR3 hydroxycarboxylic acid receptor 3
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HIST1H2AI histone cluster 1, H2ai
HSF1 heat shock transcription factor 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA0319L KIAA0319-like
LRP3 low density lipoprotein receptor-related protein 3
LYPD1 LY6/PLAUR domain containing 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MED15 mediator complex subunit 15
MFGE8 milk fat globule-EGF factor 8 protein
MOB3B MOB kinase activator 3B
MRPL41 mitochondrial ribosomal protein L41
MRPS18C mitochondrial ribosomal protein S18C
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MTA2 metastasis associated 1 family, member 2
NDE1 nudE neurodevelopment protein 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKAIN1 Na+/K+ transporting ATPase interacting 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLAC1 placenta-specific 1
PLCD1 phospholipase C, delta 1
PTPRU protein tyrosine phosphatase, receptor type, U
QPCTL glutaminyl-peptide cyclotransferase-like
RAB40AL RAB40A, member RAS oncogene family-like
RAB40C RAB40C, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RHOBTB2 Rho-related BTB domain containing 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPA4 replication protein A4, 30kDa
RPL10L ribosomal protein L10-like
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC16A4 solute carrier family 16, member 4
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SSTR4 somatostatin receptor 4
TLN1 talin 1
TMEM183A transmembrane protein 183A
TMEM209 transmembrane protein 209
TMLHE trimethyllysine hydroxylase, epsilon
TRAIP TRAF interacting protein
TRIM36 tripartite motif containing 36
TSNAXIP1 translin-associated factor X interacting protein 1
TUBA3D tubulin, alpha 3d
UBQLN4 ubiquilin 4
UPP1 uridine phosphorylase 1
ZBTB33 zinc finger and BTB domain containing 33
ZNF324 zinc finger protein 324
ZNF750 zinc finger protein 750
ZNF862 zinc finger protein 862