flunisolide-4303 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the flunisolide-4303 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ACTN2 actinin, alpha 2
ADGRG1 adhesion G protein-coupled receptor G1
AQP3 aquaporin 3 (Gill blood group)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARNT aryl hydrocarbon receptor nuclear translocator
ATN1 atrophin 1
BCL2L1 BCL2-like 1
BGN biglycan
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
C1ORF116 chromosome 1 open reading frame 116
CALR calreticulin
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCDC64 coiled-coil domain containing 64
CCL27 chemokine (C-C motif) ligand 27
CD1E CD1e molecule
CD34 CD34 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD52 CD52 molecule
CD82 CD82 molecule
CDK18 cyclin-dependent kinase 18
COL4A6 collagen, type IV, alpha 6
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSHL1 chorionic somatomammotropin hormone-like 1
DMBT1 deleted in malignant brain tumors 1
DOK3 docking protein 3
DUSP1 dual specificity phosphatase 1
FKBP5 FK506 binding protein 5
GJB4 gap junction protein, beta 4, 30.3kDa
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPR137 G protein-coupled receptor 137
GSK3A glycogen synthase kinase 3 alpha
GTPBP1 GTP binding protein 1
HMGA1 high mobility group AT-hook 1
HNMT histamine N-methyltransferase
HPX hemopexin
HR hair growth associated
HSF1 heat shock transcription factor 1
HSPG2 heparan sulfate proteoglycan 2
ICOSLG inducible T-cell co-stimulator ligand
IL12A interleukin 12A
IL36G interleukin 36, gamma
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB7 integrin, beta 7
KALRN kalirin, RhoGEF kinase
KDM5C lysine (K)-specific demethylase 5C
LIME1 Lck interacting transmembrane adaptor 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MAPK7 mitogen-activated protein kinase 7
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MINK1 misshapen-like kinase 1
MYO9B myosin IXB
NNMT nicotinamide N-methyltransferase
NRP2 neuropilin 2
PDE4A phosphodiesterase 4A, cAMP-specific
PDE9A phosphodiesterase 9A
PER1 period circadian clock 1
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAT plasminogen activator, tissue
PLD1 phospholipase D1, phosphatidylcholine-specific
PLIN2 perilipin 2
PPARD peroxisome proliferator-activated receptor delta
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRKCA protein kinase C, alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRR protein tyrosine phosphatase, receptor type, R
PTPRU protein tyrosine phosphatase, receptor type, U
PXN paxillin
RAB11B RAB11B, member RAS oncogene family
RAB28 RAB28, member RAS oncogene family
RARA retinoic acid receptor, alpha
RIMS3 regulating synaptic membrane exocytosis 3
RUNX1 runt-related transcription factor 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SFTPB surfactant protein B
SIRPA signal-regulatory protein alpha
SIX3 SIX homeobox 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNAI2 snail family zinc finger 2
SORBS3 sorbin and SH3 domain containing 3
SOX11 SRY (sex determining region Y)-box 11
SPATA1 spermatogenesis associated 1
SRSF7 serine/arginine-rich splicing factor 7
SSH3 slingshot protein phosphatase 3
ST7L suppression of tumorigenicity 7 like
TLN1 talin 1
TNNT2 troponin T type 2 (cardiac)
TNS4 tensin 4
TPSAB1 tryptase alpha/beta 1
TRIM25 tripartite motif containing 25
TRIM3 tripartite motif containing 3
WDTC1 WD and tetratricopeptide repeats 1
WT1 Wilms tumor 1
XYLB xylulokinase homolog (H. influenzae)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZBTB18 zinc finger and BTB domain containing 18
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACKR3 atypical chemokine receptor 3
ACTC1 actin, alpha, cardiac muscle 1
AKIP1 A kinase (PRKA) interacting protein 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ARL14 ADP-ribosylation factor-like 14
ATAD5 ATPase family, AAA domain containing 5
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
C17ORF53 chromosome 17 open reading frame 53
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD68 CD68 molecule
CENPJ centromere protein J
CENPO centromere protein O
CEP295 centrosomal protein 295kDa
CLDN11 claudin 11
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CTSF cathepsin F
CUL9 cullin 9
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DEPTOR DEP domain containing MTOR-interacting protein
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DTX2 deltex 2, E3 ubiquitin ligase
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELAVL2 ELAV like neuron-specific RNA binding protein 2
FAM169A family with sequence similarity 169, member A
FGD6 FYVE, RhoGEF and PH domain containing 6
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GLB1L galactosidase, beta 1-like
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2BM histone cluster 1, H2bm
HIST1H3G histone cluster 1, H3g
HIST1H4C histone cluster 1, H4c
HIST2H2AA3 histone cluster 2, H2aa3
IFI6 interferon, alpha-inducible protein 6
LOC100286895 cell division cycle 27 homolog pseudogene
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGC12488
MIS18BP1 MIS18 binding protein 1
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NME5 NME/NM23 family member 5
NPY1R neuropeptide Y receptor Y1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NRTN neurturin
PDE12 phosphodiesterase 12
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMCH pro-melanin-concentrating hormone
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRR14L proline rich 14-like
PRR15L proline rich 15-like
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBBP5 retinoblastoma binding protein 5
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEPP1 selenoprotein P, plasma, 1
SERTAD3 SERTA domain containing 3
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC35F6 solute carrier family 35, member F6
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMAD5 SMAD family member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPRYD7 SPRY domain containing 7
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEP1 telomerase-associated protein 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TM6SF1 transmembrane 6 superfamily member 1
TMEM159 transmembrane protein 159
UBE2W ubiquitin-conjugating enzyme E2W (putative)
VASH2 vasohibin 2
WDR25 WD repeat domain 25
WNT7A wingless-type MMTV integration site family, member 7A
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB38 zinc finger and BTB domain containing 38
ZNF264 zinc finger protein 264
ZNF350 zinc finger protein 350
ZNF667 zinc finger protein 667
ZNF669 zinc finger protein 669
ZNF721 zinc finger protein 721